Opioids and the Management of Chronic Severe Pain in the Elderly: Consensus Statement of an International Expert Panel with Focus on the Six Clinically Most Often Used World Health Organization step III Opioids (Buprenorphine, Fentanyl, Hydromorphone, Methadone, Morphine, Oxycodone)

Pain Practice ◽  
2008 ◽  
Vol 8 (4) ◽  
pp. 287-313 ◽  
Author(s):  
Joseph Pergolizzi ◽  
Rainer H Böger ◽  
Keith Budd ◽  
Albert Dahan ◽  
Serdar Erdine ◽  
...  
Blood ◽  
2007 ◽  
Vol 110 (4) ◽  
pp. 1092-1097 ◽  
Author(s):  
Ayalew Tefferi ◽  
Juergen Thiele ◽  
Attilio Orazi ◽  
Hans Michael Kvasnicka ◽  
Tiziano Barbui ◽  
...  

AbstractThe Janus kinase 2 mutation, JAK2617V>F, is myeloid neoplasm-specific; its presence excludes secondary polycythemia, thrombocytosis, or bone marrow fibrosis from other causes. Furthermore, JAK2617V>F or a JAK2 exon 12 mutation is present in virtually all patients with polycythemia vera (PV), whereas JAK2617V>F also occurs in approximately half of patients with essential thrombocythemia (ET) or primary myelofibrosis (PMF). Therefore, JAK2 mutation screening holds the promise of a decisive diagnostic test in PV while being complementary to histology for the diagnosis of ET and PMF; the combination of molecular testing and histologic review should also facilitate diagnosis of ET associated with borderline thrombocytosis. Accordingly, revision of the current World Health Organization (WHO) diagnostic criteria for PV, ET, and PMF is warranted; JAK2 mutation analysis should be listed as a major criterion for PV diagnosis, and the platelet count threshold for ET diagnosis can be lowered from 600 to 450 × 109/L. The current document was prepared by an international expert panel of pathologists and clinical investigators in myeloproliferative disorders; it was subsequently presented to members of the Clinical Advisory Committee for the revision of the WHO Classification of Myeloid Neoplasms, who endorsed the document and recommended its adoption by the WHO.


CoDAS ◽  
2017 ◽  
Vol 29 (5) ◽  
Author(s):  
Camila Zorzetto Carniel ◽  
Juliana Cristina Ferreira de Sousa ◽  
Carla Dias da Silva ◽  
Carla Aparecida de Urzedo Fortunato-Queiroz ◽  
Miguel Ângelo Hyppolito ◽  
...  

RESUMO Objetivo Avaliar, por meio de questionários padronizados, a qualidade de vida de idosos com deficiência auditiva diagnosticada que utilizam ou não a prótese auditiva (AASI) e de idosos sem queixa auditiva. Método Trata-se de um estudo transversal, com amostra não probabilística, distribuída em três grupos divididos da seguinte forma: 30 idosos com perda auditiva diagnosticada e com indicação para uso do aparelho de amplificação sonora individual (AASI), mas que ainda não faziam uso da prótese; 30 idosos com deficiência auditiva que usavam o AASI; e 30 idosos sem queixa auditiva. Os participantes completaram um questionário que investigava dados sociodemográficos e familiares, o Hearing Handicap Inventory for the Elderly Screening Version (HHIE-S) e o World Health Organization Quality of Life - versão breve (WHOQOL-Breve). Além das análises descritivas dos dados, foram realizados testes para comparação dos três grupos, aplicando-se a análise de variância (ANOVA) e o teste post hoc de Bonferroni. Resultados Os três grupos se diferenciaram significativamente em todos os domínios de qualidade de vida. O grupo de idosos com perda auditiva diagnosticada e com indicação para uso do AASI apresentou menores escores que o grupo de idosos com deficiência auditiva que usavam o AASI e que o grupo de referência. O grupo com AASI apresentou os melhores resultados de qualidade de vida. Conclusão A perda auditiva afeta a qualidade de vida do idoso. O uso efetivo da prótese auditiva é benéfico a esta população, melhorando suas condições de vida e saúde.


2014 ◽  
Vol 27 (8) ◽  
pp. 1243-1246 ◽  
Author(s):  
Lia Fernandes ◽  
Raimundo Mateos ◽  
Knut Engedal ◽  
Armin von Gunten ◽  
Max L. Stek ◽  
...  

With the increase in aging all over the world, and the elderly population nearly tripling from 524 million (8% of the world's population) in 2010 to 1.5 billion (16% of the world's population) in 2050, we will face new challenges and opportunities in providing healthcare. In 2050, it is estimated that Europe will see an increase of 70% in elderly population aged over 65 years, and 170% in those aged over 80 years (World Health Organization (WHO), 2011). It is vital to respond to the needs of this emerging population and the consequent rise in chronic diseases, especially dementia and mental health disorders, which will overload the healthcare system, as well as raise health and social costs, and demand new policies from national governments (World Health Organization, 2012). We urgently need to know how to organize healthcare for elderly people in the years to come.


2021 ◽  
Vol 5 (1) ◽  
pp. 404
Author(s):  
Desi Rofita ◽  
Evi Diliana Rospia ◽  
Dwi Kartika Cahyaningtyas ◽  
Catur Esty Pamungkas ◽  
Aulia Amini ◽  
...  

ABSTRAKWHO (World  Health  Organization) secara  resmi  mendeklarasikan  virus  corona (Covid-19)  sebagai  pandemi. Virus Covid-19 menyebabkan gejala seperti demam dan batuk, dan kebanyakan bisa sembuh dalam beberapa minggu. Tapi bagi sebagian orang yang berisiko tinggi (kelompok lanjut  usia  dan  orang  dengan masalah  kesehatan  menahun, seperti  penyakit  jantung,  tekanan darah  tinggi,  atau diabetes), virus corona dapat menyebabkan masalah kesehatan yang serius. Ada dua  jalur  utama  penularan COVID-19, yakni penularan droplet pernapasan dan penularan kontak dekat. Dalam rangka penanggulangan pandemi COVID-19 tidak hanya dilaksanakan dari sisi penerapan protokol kesehatan, namun juga intervensi dengan vaksinasi sebagai bagian dari upaya pencegahan dan Pengendalian COVID-19. Kegiatan vaksinasi masal ini bertujuan agar dapat terbentuk herd immunity (kekebalan kelompok) dan berkurangnya angka kematian akibat COVID-19 pada masyarakat.Jenis vaksin yang digunakan pada kegiatan vaksinasi masal ini adalah Moderna. Jumlah responden yang mengikuti kegiatan ini sebanyak 1.581 orang. Hasil pengabdian didapatkan bahwa jumlah yang melakukan vaksinasi sebanyak 1.581 orang yang terdiri remaja sebanyak 60 orang dewasa sebanyak 1497 orang dan lansia sebanyak 24 orang, diberikan vaksin sebanyak 1.536 orang, ditunda sebanyak 45 orang. Kata kunci: vaksinasi; covid-19; komunitas. ABSTRACTWHO (World Health Organization) has officially declared the coronavirus (Covid-19) as a pandemic. The Covid-19 virus causes symptoms such as fever and cough, and most recover within a few weeks. But for some people who are at high risk (the elderly and people with chronic health problems, such as heart disease, high blood pressure, or diabetes), the coronavirus can cause serious health problems. There are two main routes of transmission of COVID-19, namely respiratory droplet transmission and close contact transmission. In the context of dealing with the COVID-19 pandemic, it is not only implemented in terms of implementing health protocols but also interventions with vaccinations as part of efforts to prevent and control COVID-19. This mass vaccination activity aims to form herd immunity and reduce the mortality rate due to COVID-19 in the community. The type of vaccine used in this mass vaccination activity is Moderna. The number of respondents who participated in this activity was 1,581 people. The results of the service found that the number of people who registered for Pcare was 1,581 people, consisting of 60 teenagers, 1497 adults, and 24 elderly people, 1,536 people were given the vaccine, 45 people were delayed. Keywords: vaccination; covid-19; community. 


e-CliniC ◽  
2015 ◽  
Vol 3 (1) ◽  
Author(s):  
Inri F. Moniung ◽  
Anita E. Dundu ◽  
Herdy Munayang

Abstract: Depression is a serious problem in the society. According to World Health Organization in 2000, depression is on fourth rank in the world as the disease causing disability and will be raised to second rank of health problem in 2020. Elderly is a hard phase of human life. In this period, the elderly are often confronted with problems such as physical limitations and losing their role in society that could make them more susceptible to get depression. Moreover, elderly who stay at nursing home have the feeling as if they are not worthy anymore, be discarded from their family, and start blaming themselves. This was an analytical study with a cross-sectional research design. Level of depression of fifty elderly people will be rated using the questionnaire of Hamilton Depression Rate Scale. data were statistically analyzed (univariate and bivariate). The results showed that 4.0% elderly were normal, 34.0% had mild depression, 56.0% had moderate depression, 6.0% had severe depression. There was no relation between length of stay with level of depression among elderly in Panti Sosial Tresna Werdha Agape Tondano.Keywords: depression, elderly, Hamilton depression rate scale.Abstrak: World Health Organization menyatakan depresi berada pada urutan keempat penyakit di dunia penyebab kecacatan dan pada tahun 2020 akan meningkat menduduki peringkat kedua masalah kesehatan dunia. Masa lanjut usia merupakan tahap kehidupan yang tidak mudah. Pada periode ini lanjut usia dihadapkan dengan berbagai kendala baik kemunduran fisik maupun kehilangan peran sosialnya sehingga menyebabkan lanjut usia cenderung lebih rentan mengalami depresi. Lanjut usia yang tinggal di panti werdha karena terpaksa merasa tidak berharga, menyalahkan diri sendiri, dan merasa diri dibuang oleh keluarga. Penelitian ini bersifat analitik dengan desain potong lintang. Tingkatan depresi pada 50 orang lanjut usia dinilai dengan menggunakan kuesioner Hamilton Depression Rate Scale. Hasil penelitian diolah dengan analisis univariat dan bivariat. Hasil penelitian menunjukkan sebanyak 4,0% lanjut usia tidak mengalami depresi, 34,0% lanjut usia dengan depresi ringan, 56,0% lanjut usia dengan depresi sedang, 6,0% dengan depresi berat. Tidak terdapat hubungan lama tinggal dan tingkat depresi pada lanjut usia di Panti Sosial Tresna Werdha Agape Tondano.Kata kunci: depresi, lanjut usia, Hamilton depression rate scale


Sign in / Sign up

Export Citation Format

Share Document