Risk factors for progression of aortic arch calcification in patients on maintenance hemodialysis and peritoneal dialysis

2011 ◽  
Vol 15 (4) ◽  
pp. 460-467 ◽  
Author(s):  
Hyun Gyung KIM ◽  
Sun Wha SONG ◽  
Tae Yun KIM ◽  
Young Ok KIM
Keyword(s):  
Risk Factors ◽  
Peritoneal Dialysis ◽  
Aortic Arch ◽  
Maintenance Hemodialysis ◽  
Aortic Arch Calcification

P1258CLINICAL COMPARATIVE STUDY OF AORTIC ARCH CALCIFICATION IN PATIENTS WITH MAINTENANCE PERITONEAL DIALYSIS AND HEMODIALYSIS

2020 ◽  
Vol 35 (Supplement_3) ◽  
Author(s):  
Junhui Li ◽  
Niansong Wang
Keyword(s):  
Risk Factors ◽  
Peritoneal Dialysis ◽  
Comparative Study ◽  
Aortic Arch ◽  
Vascular Calcification ◽  
Binary Logistic Regression Analysis ◽  
Risk Of Mortality ◽  
Increased Risk ◽  
Independent Risk Factors ◽  
Aortic Arch Calcification

Abstract Background and Aims Vascular calcification is known to be an important risk factor in patients with dialysis, However, the comparative study on vascular calcification between peritoneal dialysis (PD) and hemodialysis (HD) is less. The aim of this study was to analyze the presence, risk factors of aortic arch calcification (AAC), and compare the prognosis in maintenance PD and HD patients. Method Using retrospective analysis method, 177 patients with PD and 147 patients with HD were included in the study. The extent of AAC was evaluated by chest X-ray examination. The demographic characteristics and clinical data were collected and compared between PD group and HD group. Binary logistic regression analysis was performed to evaluate risk factors associated with the aortic arch calcification. Results The incidence of AAC in HD group (59.86%) was significantly higher than that in PD group (37.29%). Multivariate analysis showed that age, residual renal function (RRF) and serum phosphate were the independent risk factors for calcification of PD patients and the odds ratio (OR) values were 1.133, 1.039, 0.762 and 18.186, respectively. Similarly, age, RRF, calcium-phosphorus product and LDL were the risk factors of HD patients and their respective OR values were 1.125, 0.509, 2.755 and 3.221. Compared with patients without AAC, the presence of moderate-severe AAC was associated with greater risk of mortality, and the OR values were 17.833 and 20.056 in PD group and HD group, respectively. Conclusion Our findings suggest that the AAC was more common in HD patients. Older age and lower RRF are common independent risk factors for AAC in PD and HD patients. Moderate to severe AAC a ppears to be associated with increased risk of mortality.

scholarly journals Association Between Risk Factors Including Bone-Derived Biomarkers and Aortic Arch Calcification in Maintenance Hemodialysis Patients

2018 ◽  
Vol 43 (5) ◽  
pp. 1554-1562 ◽  
Author(s):  
Kosaku Nitta ◽  
Norio Hanafusa ◽  
Masayuki Okazaki ◽  
Mizuki Komatsu ◽  
Hiroshi Kawaguchi ◽  
...  
Keyword(s):  
Risk Factors ◽  
Aortic Arch ◽  
Hemodialysis Patients ◽  
Maintenance Hemodialysis ◽  
Maintenance Hemodialysis Patients ◽  
Aortic Arch Calcification

scholarly journals Severe aortic arch calcification predicts mortality in patients undergoing peritoneal dialysis

2017 ◽  
Vol 116 (5) ◽  
pp. 366-372 ◽  
Author(s):  
Ching-Fang Wu ◽  
Yee-Fan Lee ◽  
Wen-Jeng Lee ◽  
Chi-Ting Su ◽  
Lukas Jyuhn-Hsiarn Lee ◽  
...  
Keyword(s):  
Peritoneal Dialysis ◽  
Aortic Arch ◽  
Aortic Arch Calcification

Aortic Arch Calcification and Bone-Associated Molecules in Peritoneal Dialysis Patients

2019 ◽  
Vol 47 (Suppl. 2) ◽  
pp. 81-87
Author(s):  
Misao Tsukada ◽  
Naoko Miwa ◽  
Norio Hanafusa ◽  
Nobue Tanaka ◽  
Ken Tsuchiya ◽  
...  
Keyword(s):  
Peritoneal Dialysis ◽  
Aortic Arch ◽  
Pulse Wave ◽  
Fibroblast Growth Factor 23 ◽  
Fatal Complication ◽  
X Ray ◽  
Plain Chest ◽  
Chest X Ray ◽  
Aortic Arch Calcification

Background/Aims: Aortic arch calcification (AoAC) is a fatal complication in dialysis. AoAC progression-related molecules in continuous ambulatory peritoneal dialysis (CAPD) remain unclear. Methods: AoAC was estimated using plain chest radiography scoring (AoACS) in 30 CAPD patients (age 49.3 ± 13.4 years). AoAC progression was defined as increased AoACS on follow-up chest X-ray at the end of the study (progressors). Fibroblast growth factor-23 and osteoprotegerin (OPG) were measured. Results: Median follow-up was 38.5 months. Progressors were older, had shorter PD vintage, higher body mass index, and higher serum OPG levels (255.6 ± 109.2 pg/mL) than nonprogressors (183.4 ± 68.2 pg/mL; p = 0.0400). Progressors also showed higher pulse pressure (62.4 ± 20.0 mm Hg) and pulse wave velocity (1,909.9 ± 310.6 cm/s) than nonprogressors (48.5 ± 13.6 mm Hg; p = 0.0030 and 1,390.1 ± 252.8 cm/s; p = 0.0005, respectively). Conclusion: AoAC progression was associated with increased aortic stiffness. OPG may be associated with AoAC progression in CAPD.

scholarly journals Aortic Arch Calcification and Cardiomegaly Are Associated with Overall and Cardiovascular Mortality in Hemodialysis Patients

2021 ◽  
Vol 11 (7) ◽  
pp. 657
Author(s):  
Shih-Hsiang Ou ◽  
Yi-Hsueh Liu ◽  
Tung-Ling Chung ◽  
Jiun-Chi Huang ◽  
Pei-Yu Wu ◽  
...  
Keyword(s):  
Aortic Arch ◽  
Clinical Outcomes ◽  
Cardiovascular Mortality ◽  
Multivariable Analysis ◽  
Predictive Ability ◽  
Hemodialysis Patients ◽  
Maintenance Hemodialysis ◽  
Cardiothoracic Ratio ◽  
Cardiovascular Morbidity And Mortality ◽  
Aortic Arch Calcification

Patients with end-stage renal disease have a higher risk of cardiovascular morbidity and mortality. In this study, we investigated the predictive ability of a combination of cardiothoracic ratio (CTR) and aortic arch calcification (AoAC) for overall and cardiovascular mortality in patients receiving hemodialysis. We also evaluated the predictive power of AoAC and CTR for clinical outcomes. A total of 365 maintenance hemodialysis patients were included, and AoAC and CTR were measured using chest radiography at enrollment. We stratified the patients into four groups according to a median AoAC score of three and CTR of 50%. Multivariable Cox proportional hazards analysis was used to identify the risk factors of mortality. The predictive performance of the model for clinical outcomes was assessed using the χ2 test. Multivariable analysis showed that, compared to the AoAC < 3 and CTR < 50% group, the AoAC ≥ 3 and CTR < 50% group (hazard ratio [HR], 4.576; p < 0.001), and AoAC ≥ 3 and CTR ≥ 50% group (HR, 5.912; p < 0.001) were significantly associated with increased overall mortality. In addition, the AoAC < 3 and CTR ≥ 50% (HR, 3.806; p = 0.017), AoAC ≥ 3 and CTR < 50% (HR, 4.993; p = 0.002), and AoAC ≥ 3 and CTR ≥ 50% (HR, 8.614; p < 0.001) groups were significantly associated with increased cardiovascular mortality. Furthermore, adding AoAC and CTR to the basic model improved the predictive ability for overall and cardiovascular mortality. The patients who had a high AoAC score and cardiomegaly had the highest overall and cardiovascular mortality among the four groups. Furthermore, adding AoAC and CTR improved the predictive ability for overall and cardiovascular mortality in the hemodialysis patients.

scholarly journals Progression of Aortic Arch Calcification Over 1 Year Is an Independent Predictor of Mortality in Incident Peritoneal Dialysis Patients

PLoS ONE ◽  
2012 ◽  
Vol 7 (11) ◽  
pp. e48793 ◽  
Author(s):  
Mi Jung Lee ◽  
Dong Ho Shin ◽  
Seung Jun Kim ◽  
Hyung Jung Oh ◽  
Dong Eun Yoo ◽  
...  
Keyword(s):  
Peritoneal Dialysis ◽  
Aortic Arch ◽  
Independent Predictor ◽  
Dialysis Patients ◽  
Aortic Arch Calcification
Sign in / Sign up

Export Citation Format

Share Document