Back-scattered electron imaging and elemental analysis of retrieved bone tissue following sinus augmentation with deproteinized bovine bone or biphasic calcium phosphate

2010 ◽  
pp. no-no ◽  
Author(s):  
Christer Lindgren ◽  
Mats Hallman ◽  
Lars Sennerby ◽  
Rachel Sammons
Keyword(s):  
Calcium Phosphate ◽  
Bone Tissue ◽  
Elemental Analysis ◽  
Biphasic Calcium Phosphate ◽  
Bovine Bone ◽  
Scattered Electron ◽  
Sinus Augmentation ◽  
Electron Imaging ◽  
Deproteinized Bovine Bone

scholarly journals Histological Comparison between Biphasic Calcium Phosphate and Deproteinized Bovine Bone on Critical-Size Bone Defects

2021 ◽  
Vol 32 (1) ◽  
pp. 26-33
Author(s):  
Marina Araujo Brito ◽  
Leomar Emanuel Almeida Mecca ◽  
Thais dos Santos Sedoski ◽  
Tayline Mroczek ◽  
Marcela Claudino ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Bone Tissue ◽  
Biphasic Calcium Phosphate ◽  
Bone Repair ◽  
Critical Size ◽  
Blood Clot ◽  
Bone Defects ◽  
Bovine Bone ◽  
Tissue Area ◽  
Deproteinized Bovine Bone

Abstract The limited options for bone repair have led to an extensive research of the field and the development of alloplastic and xenogeneic grafts. The purpose of this study was to evaluate bone repair with two bone substitutes: deproteinized bovine bone (DBB) and biphasic calcium phosphate ceramic (BCP) in critical-size defect. A total of 8-mm defects were made in the parietal bones of rabbits (n=12). The animals were divided into three experimental groups: sham (defect filled with a blood clot), DBB (defect filled with DBB), and BCP (defect filled with BCP). After the experimental periods of 15 and 45 days, the animals were euthanized and submitted to histomorphometric analysis. The total defect area, mineralized tissue area, biomaterial area, and soft tissue area were evaluated. A greater amount of immature bone tissue and biomaterial particles were observed in the BCP group compared to DBB and sham at 45 days (p<0.05). There was no difference in the qualitative pattern of bone deposition between DBB and BCP. However, the sham group did not show osteoid islands along with the defect, presenting a greater amount of collagen fibers as well in relation to the DBB and BCP groups. There was a greater number of inflammatory cells in the DBB at 45 days compared to BCP and sham groups. In conclusion, BCP and DBB are options for optimizing the use of bone grafts for maxillofacial rehabilitation. Bone defects treated with BCP showed greater deposition of bone tissue at 45 days.

scholarly journals Assessment of Bone Healing in Rabbit Calvaria Grafted with Three Different Biomaterials

2014 ◽  
Vol 25 (5) ◽  
pp. 379-384 ◽  
Author(s):  
Carlos Alberto Yoshihiro Takauti ◽  
Fabio Futema ◽  
Rui Barbosa de Brito Junior ◽  
Aline Corrêa Abrahão ◽  
Claudio Costa ◽  
...  
Keyword(s):  
New Zealand ◽  
Calcium Phosphate ◽  
Biphasic Calcium Phosphate ◽  
Parietal Bone ◽  
The Other ◽  
Bovine Bone ◽  
Bone Induction ◽  
Induction Process ◽  
New Zealand White Rabbits ◽  
Deproteinized Bovine Bone

This study evaluated the bone regeneration process in rabbit calvaria induced by three types of biomaterials: two xenogenous, consisting of deproteinized bovine bone, while the other was alloplastic, based on biphasic calcium phosphate. Five New Zealand white rabbits weighing between 2,900 and 3,500 g were submitted to four standard 8 mm-diameter perforations at the parietal bone. Three perforations were filled with three grafts and biomaterials, two of them received bovine Bio-Oss(r) and Endobon(r) Xenograft Granules, and the other consisted of fully alloplastic Straumann(r) Bone Ceramic. The fourth remaining cavity was used as control with coagulum. After eight weeks, the animals were sacrificed, and the samples were prepared for morphometric and qualitative analysis. The cavities filled with alloplastic biomaterials showed higher percentages of newly formed bone (p<0.05), while the cavities with xenogenous biomaterials showed higher amount of residual graft (p<0.05). Although the results showed greater bone formation with Straumann(r) Bone Ceramic, further studies are required to prove which is the more effective biomaterial for bone induction process.

scholarly journals Histological and Histomorphometric Human Results of HA-Beta-TCP 30/70 Compared to Three Different Biomaterials in Maxillary Sinus Augmentation at 6 Months: A Preliminary Report

2015 ◽  
Vol 2015 ◽  
pp. 1-7 ◽  
Author(s):  
Susanna Annibali ◽  
Giovanna Iezzi ◽  
Gian Luca Sfasciotti ◽  
Maria Paola Cristalli ◽  
Iole Vozza ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Preliminary Report ◽  
Biphasic Calcium Phosphate ◽  
Close Contact ◽  
Bone Allograft ◽  
Bovine Bone ◽  
Histomorphometric Analysis ◽  
Sinus Augmentation ◽  
Implant Placement ◽  
Posterior Maxilla

Objective. The aim of this investigation was to examine the bone regenerative potential of newly biphasic calcium phosphate ceramics (HA-β-TCP 30/70), by assessing histological and histomorphometric results of human specimens retrieved from sinuses augmented with HA-β-TCP 30/70, and comparing them to anorganic bovine bone (ABB), mineralized solvent-dehydrated bone allograft (MSDBA), and equine bone (EB), after a healing period of 6 months.Materials and Methods. Four consecutive patients with edentulous atrophic posterior maxilla were included in this report. A two-stage procedure was carried out for sinus augmentation with HA-β-TCP 30/70, ABB, MSDBA, and EB. After 6 months, specimens were retrieved at the time of implant placement and processed for histological and histomorphometric analyses.Results. At histological examination, all biomaterials were in close contact with the newly formed bone and showed the same pattern of bone formation; the grafted granules were surrounded by a bridge-like network of newly formed bone. A limited number of ABB particles were partially covered by connective tissue. The histomorphometric analysis revealed 30.2% newly formed bone for Ha-β-TCP 30/70, 20.1% for ABB, 16.4% for MSDBA, and 21.9% for EB.Conclusions. Within the limitations of the present investigation, these results support the successful use of HA-β-TCP 30/70 for sinus augmentation.

scholarly journals Bone Formation with Deproteinized Bovine Bone Mineral or Biphasic Calcium Phosphate in the Presence of Autologous Platelet Lysate: Comparative Investigation in Rabbit

2014 ◽  
Vol 2014 ◽  
pp. 1-10 ◽  
Author(s):  
Carole Chakar ◽  
Nada Naaman ◽  
Emmanuel Soffer ◽  
Nicolas Cohen ◽  
Nada El Osta ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Biphasic Calcium Phosphate ◽  
Bone Substitutes ◽  
Platelet Lysate ◽  
Bovine Bone ◽  
Residual Material ◽  
Bovine Bone Mineral ◽  
Deproteinized Bovine Bone Mineral ◽  
Autologous Platelet ◽  
Deproteinized Bovine Bone

Bone substitutes alone or supplemented with platelet-derived concentrates are widely used to promote bone regeneration but their potency remains controversial. The aim of this study was, therefore, to compare the regenerative potential of preparations containing autologous platelet lysate (APL) and particles of either deproteinized bovine bone mineral (DBBM) or biphasic calcium phosphate (BCP), two bone substitutes with different resorption patterns. Rabbit APL was prepared by freeze-thawing a platelet suspension. Critical-size defects in rabbit femoral condyle were filled with DBBM or DBBM+APL and BCP or BCP+APL. Rabbits were sacrificed after six weeks and newly formed bone and residual implanted material were evaluated using nondemineralized histology and histomorphometry. New bone was observed around particles of all fillers tested. In the defects filled with BCP, the newly formed bone area was greater (70%;P<0.001) while the residual material area was lower (60%;P<0.001) than that observed in those filled with DBBM. New bone and residual material area of defects filled with either APL+DBBM or APL+BCP were similar to those observed in those filled with the material alone. In summary, osteoconductivity and resorption of BCP were greater than those of DBBM, while APL associated with either DBBM or BCP did not have an additional benefit.

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