scholarly journals Why do young women smoke? V. Role of direct and interactive effects of nicotinic cholinergic receptor gene variation on neurocognitive function

2008 ◽  
Vol 7 (2) ◽  
pp. 164-172 ◽  
Author(s):  
A. Rigbi ◽  
K. Kanyas ◽  
A. Yakir ◽  
L. Greenbaum ◽  
Y. Pollak ◽  
...  
Keyword(s):  
Young Women ◽  
Receptor Gene ◽  
Cholinergic Receptor ◽  
Neurocognitive Function ◽  
Interactive Effects ◽  
Gene Variation ◽  
Nicotinic Cholinergic Receptor

scholarly journals Estrogen dependence of the renal vasodilatory effect of nicotine in rats: Role of α7 nicotinic cholinergic receptor/eNOS signaling

Life Sciences ◽  
2011 ◽  
Vol 88 (3-4) ◽  
pp. 187-193 ◽  
Author(s):  
Mahmoud M. El-Mas ◽  
Sahar M. El-gowilly ◽  
Eman Y. Gohar ◽  
Abdel-Rheem M. Ghazal ◽  
Abdel A. Abdel-Rahman
Keyword(s):  
Cholinergic Receptor ◽  
Vasodilatory Effect ◽  
Nicotinic Cholinergic Receptor ◽  
Estrogen Dependence

scholarly journals Associations of rare nicotinic cholinergic receptor gene variants to nicotine and alcohol dependence

2016 ◽  
Vol 171 (8) ◽  
pp. 1057-1071 ◽  
Author(s):  
Lingjun Zuo ◽  
Yunlong Tan ◽  
Chiang-Shan R. Li ◽  
Zhiren Wang ◽  
Kesheng Wang ◽  
...  
Keyword(s):  
Alcohol Dependence ◽  
Receptor Gene ◽  
Cholinergic Receptor ◽  
Gene Variants ◽  
Nicotinic Cholinergic Receptor

Epistasis between APOE and nicotinic receptor gene CHRNA4 in age related cognitive function and decline

2010 ◽  
Vol 16 (3) ◽  
pp. 424-432 ◽  
Author(s):  
IVAR REINVANG ◽  
ASTRI J. LUNDERVOLD ◽  
EIKE WEHLING ◽  
HELGE ROOTWELT ◽  
THOMAS ESPESETH
Keyword(s):  
Cognitive Function ◽  
Nicotinic Receptor ◽  
Memory Performance ◽  
Receptor Gene ◽  
Cholinergic Receptor ◽  
Negative Influence ◽  
Genetic Effects ◽  
Interactive Effects ◽  
Carrier Status ◽  
Age Related

AbstractHealthy participants (n = 237) aged 45–79 were tested neuropsychologically with tests of memory, speed, and cognitive control and followed up for 3–5 years (mean, 3.4 years). The sample was genotyped for apolipoprotein E (APOE) and CHolinergic Receptor for Nicotine Alpha 4 (CHRNA4), and genetic effects on cognitive function at initial testing and on cognitive decline was studied. We predicted relatively stronger effects of APOE on memory, and of CHRNA4 on speeded tasks. The predictions were partially confirmed, but we found interactive effects of APOE and CHRNA4 in several cognitive domains. Being an APOE ε4/CHRNA4 TT carrier was associated with slower and less efficient performance, and with steeper decline in speed tasks and in delayed recall. Age dependent genetic effects were found for both APOE and CHRNA4, where old participants (60–79 years) showed a negative influence of TT carrier status on initial memory performance, but a tendency for steeper memory decline in ε4 carriers. Inconsistent and small effects of APOE reported in previous studies of healthy groups may be caused by failure to consider epistasis of APOE with nicotinic receptor and other genes. (JINS, 2010, 16, 424–432.)

Parenting Behaviors and Anxiety in Young Adults

2015 ◽  
Vol 36 (3) ◽  
pp. 170-176 ◽  
Author(s):  
Erin N. Stevens ◽  
Joseph R. Bardeen ◽  
Kyle W. Murdock
Keyword(s):  
Effortful Control ◽  
Parenting Behaviors ◽  
Protective Role ◽  
Anxiety Symptoms ◽  
Interactive Effects ◽  
Parental Overprotection ◽  
High Control ◽  
Development Of Anxiety ◽  
The Relationship

Parenting behaviors – specifically behaviors characterized by high control, intrusiveness, rejection, and overprotection – and effortful control have each been implicated in the development of anxiety pathology. However, little research has examined the protective role of effortful control in the relation between parenting and anxiety symptoms, specifically among adults. Thus, we sought to explore the unique and interactive effects of parenting and effortful control on anxiety among adults (N = 162). Results suggest that effortful control uniquely contributes to anxiety symptoms above and beyond that of any parenting behavior. Furthermore, effortful control acted as a moderator of the relationship between parental overprotection and anxiety, such that overprotection is associated with anxiety only in individuals with lower levels of effortful control. Implications for potential prevention and intervention efforts which specifically target effortful control are discussed. These findings underscore the importance of considering individual differences in self-regulatory abilities when examining associations between putative early-life risk factors, such as parenting, and anxiety symptoms.

The Estimation of prostate specific antigen (PSA) concentrations in patients with prostatitis by fully automated ELISA technique.

2020 ◽  
Vol 3 (11) ◽  
pp. 1100-1104
Author(s):  
Hussein Naeem Aldhaheri ◽  
Ihsan Edan AlSaimary ◽  
Murtadha Mohammed ALMusafer
Keyword(s):  
Personal Information ◽  
Receptor Gene ◽  
Specific Antigen ◽  
Gene Clusters ◽  
Control Group ◽  
P Value ◽  
Group Data ◽  
Elisa Technique ◽  
And Control

      The Aim of this study was to determine Immunogenetic expression of  Toll-like receptor gene clusters related to prostatitis, to give acknowledge about Role of TLR in prostatitis immunity in men from Basrah and Maysan provinces. A case–control study included 135 confirmed prostatitis patients And 50 persons as a control group. Data about age, marital status, working, infertility, family history and personal information like (Infection, Allergy, Steroid therapy, Residency, Smoking, Alcohol Drinking, Blood group, Body max index (BMI) and the clinical finding for all patients of Prostatitis were collected. This study shows the effect of PSA level in patients with prostatitis and control group, with P-value <0.0001 therefore the study shows a positive significant between elevated PSA levels and Prostatitis.

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