IgG SUBCLASS DISTRIBUTION OF SERUM ANTIBODIES AGAINST LIPOPOLYSACCHARIDE FROM BACTEROIDES GINGIVALIS IN PERIODONTAL HEALTH AND DISEASE

2009 ◽  
Vol 95C (1-6) ◽  
pp. 41-46 ◽  
Author(s):  
Karl Schenck ◽  
Terje E. Michaelsen
Keyword(s):  
Igg Subclass ◽  
Serum Antibodies ◽  
Periodontal Health ◽  
Health And Disease ◽  
Bacteroides Gingivalis

scholarly journals Diagnostic accuracy of a point‐of‐care aMMP‐8 test in the discrimination of periodontal health and disease

2021 ◽  
Author(s):  
Ke Deng ◽  
George Pelekos ◽  
Lijian Jin ◽  
Maurizio S. Tonetti
Keyword(s):  
Diagnostic Accuracy ◽  
Point Of Care ◽  
Periodontal Health ◽  
Health And Disease

scholarly journals Gingival crevicular fluid level of soluble triggering recep-tor expressed on myeloid cells-1(strem-1) in periodontal health and disease: a case-control study

2017 ◽  
Vol 5 (2) ◽  
pp. 83
Author(s):  
Surabhi Gigras ◽  
Sudhir R Patil ◽  
Veena HR ◽  
Sneha Dani
Keyword(s):  
Chronic Periodontitis ◽  
Myeloid Cells ◽  
Cell Surface Receptor ◽  
Periodontal Health ◽  
Group Iii ◽  
Root Planing ◽  
Group I ◽  
Health And Disease ◽  
Group Ii ◽  
Crevicular Fluid

Background: The Triggering Receptor Expressed On Myeloid Cells-1(TREM-1) is a cell-surface receptor of the immunoglobulin superfamily and found to be involved in the amplification of the inflammatory response to various microbial infections, including periodontal diseases.Objectives: The present study was designed to examine gingivalcrevicular fluid(GCF) levels of soluble TREM-1 (sTREM-1) levels in periodontal health and disease as well as evaluate the effect of scaling and/or root planing on the same.Methods: Based on gingival index, probing pocket depth, clinical attachment level, and radiologic parameters (bone loss), 45 subjects were initially divided into three groups- Group, I (Periodontally healthy), Group II (Gingivitis) and Group III (Chronic Periodontitis).From each of the subjects, GCF sample was collected at baseline and scaling and/or root planing was instituted in group II and group III patients. GCF samples were subsequently collected at eight-week interval. Levels of sTREM-1 in collected GCF samples were estimated using enzyme-linked immunosorbent assay.Results: The lowest GCF levels of sTREM-1 were found in periodontal health (69.50±1.8pg/ml) followed by gingivitis (257.17±79pg/ml) and chronic periodontitis (3658.14±55pg/ml) in increasing order, suggesting that levels of sTREM-1 in crevicular fluid increased with the severity of periodontal disease. sTREM-1 levels decreased significantly from baseline to the end of 8 weeks following non-surgical periodontal therapy.Conclusion: Increased GCF levels of sTREM-1 from periodontal health to disease strengthen its association with periodontal status.

scholarly journals Subgingival lipid A profile and endotoxin activity in periodontal health and disease

2018 ◽  
Vol 23 (9) ◽  
pp. 3527-3534 ◽  
Author(s):  
Alexander Strachan ◽  
Zoe Harrington ◽  
Clare McIlwaine ◽  
Matthew Jerreat ◽  
Louise A. Belfield ◽  
...  
Keyword(s):  
Lipid A ◽  
Periodontal Health ◽  
Endotoxin Activity ◽  
Health And Disease

scholarly journals Qat Chewing and Periodontal Pathogens in Health and Disease: Further Evidence for a Prebiotic-Like Effect

2015 ◽  
Vol 2015 ◽  
pp. 1-7 ◽  
Author(s):  
Abdulrahman Al-Alimi ◽  
Tara Taiyeb-Ali ◽  
Nasruddin Jaafar ◽  
Nezar Noor Al-hebshi
Keyword(s):  
Multiple Comparisons ◽  
Study Groups ◽  
Periodontal Pathogens ◽  
Periodontal Health ◽  
Significance Level ◽  
Parvimonas Micra ◽  
Nominal Significance ◽  
Health And Disease ◽  
Filifactor Alocis ◽  
Total Bacteria

Aim. Qat chewing has been reported to induce subgingival microbial shifts suggestive of prebiotic-like properties. The objective here was to assess the effect of qat chewing on a panel of classical and new putative periopathogens in health and periodontitis.Materials and Methods. 40 qat chewers and 40 nonchewers, equally stratified by periodontal health status, were recruited. Taqman, real-time PCR was used to quantify total bacteria,Porphyromonas gingivalis,Tannerella forsythia,Treponema denticola,Parvimonas micra,Filifactor alocis, Synergistetes, and TM7s in pooled subgingival biofilm samples. Differences in microbial parameters between the study groups were analysed using ordinal regression.Results. In health, the qat chewers harboured significantly lower relative counts ofP. gingivalis,T. forsythia, Synergistetes, and TM7s after adjustment for multiple comparisons (P≤0.007). At nominal significance level, they also carried lower counts of TM7s andP. micra(P≤0.05). In periodontitis, the chewers had lower counts of all taxa; however, onlyT. denticolawithstood correction for multiple comparisons (P≤0.0063).Conclusions. Qat chewing is associated with lower proportions of periopathogens, particularly in subjects with healthy periodontium, which supports previous reports of its prebiotic-like properties. This potentially beneficial biological effect can be exploited by attempting to isolate the active fraction.

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