SUBCHRONIC TOXICITY STUDY OF EASTERN BLACK NIGHTSHADE (SOLANUM PTYCANTHUM) BERRIES IN SPRAGUE-DAWLEY RATS

1993 ◽  
Vol 13 (2) ◽  
pp. 91-97 ◽  
Author(s):  
KENNETH A. VOSS ◽  
WILLIAM J. CHAMBERLAIN ◽  
LUCAS H. BRENNECKE
Keyword(s):  
Toxicity Study ◽  
Sprague Dawley ◽  
Subchronic Toxicity ◽  
Eastern Black Nightshade ◽  
Solanum Ptycanthum ◽  
Black Nightshade ◽  
Sprague Dawley Rats

Safety assessment of Hwangryunhaedok-tang: Subchronic toxicity study in Crl:CD Sprague Dawley rats

2013 ◽  
Vol 221 ◽  
pp. S211
Author(s):  
Meeyoung Lee ◽  
Changseob Seo ◽  
Young Bum Kim ◽  
Shin Hyeunkyoo
Keyword(s):  
Safety Assessment ◽  
Toxicity Study ◽  
Sprague Dawley ◽  
Subchronic Toxicity ◽  
Sprague Dawley Rats

Subchronic toxicity study of ozonated and ozonated/chlorinated humic acids in Sprague-Dawley rats: a model system for drinking water disinfection

1991 ◽  
Vol 25 (1) ◽  
pp. 93-98 ◽  
Author(s):  
F. Bernard Daniel ◽  
Merrel Robinson ◽  
H. Paul Ringhand ◽  
Judy A. Stober ◽  
Norbert P. Page ◽  
...  
Keyword(s):  
Drinking Water ◽  
Humic Acids ◽  
Model System ◽  
Water Disinfection ◽  
Toxicity Study ◽  
Sprague Dawley ◽  
Subchronic Toxicity ◽  
Sprague Dawley Rats ◽  
Drinking Water Disinfection

Subchronic Toxicity Study of 1,1-Dichloro-2-Propanone in Sprague-Dawley Rats

1993 ◽  
Vol 16 (3) ◽  
pp. 293-305
Author(s):  
F. B. Daniel ◽  
Merrel Robinson ◽  
Greg R. Olson ◽  
J. Peter Bercz ◽  
Norbert P. Page
Keyword(s):  
Toxicity Study ◽  
Sprague Dawley ◽  
Subchronic Toxicity ◽  
Sprague Dawley Rats

A 90−day subchronic toxicity study of transgenic cotton expressing Cry1Ac, Cry2A and CP4−EPSPS proteins in Sprague−Dawley rats

2020 ◽  
Vol 146 ◽  
pp. 111783
Author(s):  
Qasim Ali ◽  
Ibrahim Bala Salisu ◽  
Ahmad Ali Shahid ◽  
Ayesha Liaqat ◽  
Abdul Qayyum Rao
Keyword(s):  
Transgenic Cotton ◽  
Toxicity Study ◽  
Sprague Dawley ◽  
Subchronic Toxicity ◽  
Sprague Dawley Rats ◽  
Cp4 Epsps

scholarly journals Acute and Subchronic Oral Toxicity of Oil Palm Puree in Sprague–Dawley Rats

2020 ◽  
Vol 17 (10) ◽  
pp. 3404
Author(s):  
Zaida Zainal ◽  
Augustine Ong ◽  
Choo Yuen May ◽  
Sui Kiat Chang ◽  
Afiqah Abdul Rahim ◽  
...  
Keyword(s):  
Lethal Dose ◽  
Pharmaceutical Formulations ◽  
Toxicity Study ◽  
Sprague Dawley ◽  
Oral Toxicity ◽  
Subchronic Toxicity ◽  
Organ Weights ◽  
Sprague Dawley Rats ◽  
Adverse Effect Level ◽  
Effect Level

Palm puree is rich in antioxidants and is produced via blending various proportions of mesocarp fibre and crude palm oil. The aim of this study was to assess the acute and subchronic toxicity of palm puree in male and female Sprague–Dawley rats. For the acute toxicity study, animals administered single palm-puree doses (2000 mg kg−1) by gavage were observed daily for 14 d. For the subchronic toxicity study, the rats were administered 500, 1000, or 2000 mg kg−1 palm puree daily for 28 d. We evaluated body and organ weights; performed haematological, biochemical, and histopathological analyses of blood and organ samples during and after treatment; and calculated the oral no-observed-adverse-effect level (NOAEL). The toxicity studies showed no signs of toxicity or mortality. The haematological, biochemical, and histopathological analyses and body and organ weights indicated no evidence of substantial toxicity at any dose of palm puree. The oral lethal dose and NOAEL for the palm puree were greater than 2000 mg kg−1 d−1 over 28 d. To the best of our knowledge, the present study is the first to confirm the safety of palm puree as a novel functional food. These encouraging results warrant further studies to elucidate its potential for pharmaceutical formulations.

scholarly journals Subchronic toxicity study of standardized methanolic extract of Mitragyna speciosa Korth in Sprague-Dawley Rats

2015 ◽  
Vol 9 ◽  
Author(s):  
Mohd U. Ilmie ◽  
Hasnan Jaafar ◽  
Sharif M. Mansor ◽  
Jafri M. Abdullah
Keyword(s):  
Methanolic Extract ◽  
Toxicity Study ◽  
Sprague Dawley ◽  
Subchronic Toxicity ◽  
Mitragyna Speciosa ◽  
Sprague Dawley Rats

scholarly journals Safety assessment of So-cheong-ryong-tang: Subchronic toxicity study in Crl:CD Sprague Dawley rats

2014 ◽  
Vol 9 (6) ◽  
pp. 2273-2282 ◽  
Author(s):  
MEE-YOUNG LEE ◽  
CHANG-SEOB SEO ◽  
SHIN-WOO CHA ◽  
HYEUN-KYOO SHIN
Keyword(s):  
Safety Assessment ◽  
Toxicity Study ◽  
Sprague Dawley ◽  
Subchronic Toxicity ◽  
Sprague Dawley Rats

A subchronic toxicity study of elemental Nano-Se in Sprague-Dawley rats

Life Sciences ◽  
2005 ◽  
Vol 76 (17) ◽  
pp. 1989-2003 ◽  
Author(s):  
X. Jia ◽  
N. Li ◽  
J. Chen
Keyword(s):  
Toxicity Study ◽  
Sprague Dawley ◽  
Subchronic Toxicity ◽  
Sprague Dawley Rats

Subchronic Toxicity Study of 1,3-Dichloropropanone in Sprague-Dawley Rats

1993 ◽  
Vol 16 (4) ◽  
pp. 341-350
Author(s):  
F. B. Daniel ◽  
M. Robinson ◽  
Judy A. Stober ◽  
G. R. Olson ◽  
Norbert P. Page
Keyword(s):  
Toxicity Study ◽  
Sprague Dawley ◽  
Subchronic Toxicity ◽  
Sprague Dawley Rats

scholarly journals Subchronic toxicity study of β-hydroxy-β-methylbutyric free acid in Sprague–Dawley rats

2014 ◽  
Vol 67 ◽  
pp. 145-153 ◽  
Author(s):  
John C. Fuller ◽  
Lawrence H. Arp ◽  
Lisa M. Diehl ◽  
Kelly L. Landin ◽  
Shawn M. Baier ◽  
...  
Keyword(s):  
Free Acid ◽  
Toxicity Study ◽  
Sprague Dawley ◽  
Subchronic Toxicity ◽  
Sprague Dawley Rats
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