An Autoradiographic Study of the Intestinal Absorption of Palmitic and Oleic Acid

1973 ◽  
Vol 89 (3) ◽  
pp. 306-317 ◽  
Author(s):  
By Ulf Haglund ◽  
Mats Jodal ◽  
Ove Lundgren
1958 ◽  
Vol 34 (5) ◽  
pp. 901-909 ◽  
Author(s):  
Ervin Kaplan ◽  
Bernard D. Edidin ◽  
Robert C. Fruin ◽  
Lyle A. Baker

1960 ◽  
Vol 199 (6) ◽  
pp. 1008-1010 ◽  
Author(s):  
C.S. Narayana Setty ◽  
A. C. Ivy

A basal sterol-free diet consisting of casein, 18%; dextrin, 57%; oleic acid, 9%; U.S.P. salt mixture, 2%; yeast, 5%; and cellulose, 9%; along with 1% sulfasuxidine and 0.2% streptomycin sulfate was fed to eight rats during a control period of 12 days, the feces being collected under alcohol the last 4 days and assayed for digitonide sterol. The experiment was repeated with the addition of 28 mg of coprostanol to the diet. It was found that from 41 to 61% (average 48%) of the coprostanol was absorbed. The relation of chemical structure to the absorbability of cholesterol derivatives is discussed with the finding that all absorbable cholesterol derivatives have the ‘chair’ conformation, but are not alike in digitonide formation and Liebermann-Burchard color reaction.


1984 ◽  
Vol 40 (6) ◽  
pp. 1156-1164 ◽  
Author(s):  
G V Vahouny ◽  
W Chalcarz ◽  
S Satchithanandam ◽  
I Adamson ◽  
D M Klurfeld ◽  
...  

1975 ◽  
Vol 65 (2) ◽  
pp. 383-397 ◽  
Author(s):  
H Carlier ◽  
J Bezard

Intestinal absorption of [3H]octanoic acid and [3H]decanoic acid was investigated in the rat by electron microscope autoradiography. The common duct (bile and pancreatic common duct) of the rats was diverted and a loop of the duodenum was cannulated 24 h later. The lipid mixture to be investigated was introduced into each experimental loop, and after 15 min or less the loop was removed. One part of each loop was used to determine the distribution of radioactivity in different lipid fractions, and an autoradiographic study was performed on the other part of the loop. Radioactivity distribution studies confirmed that medium chain fatty acids are absorbed in their nonesterified form and established that these fatty acids are absorbed much more rapidly than oleic acid. Autoradiographic studies indicated that the medium chain fatty acids are taken up in a molecular or aggregate molecular form, leave the epithelial cells by way of the lateral plasma membrane, and are next found in the blood capillaries. Our results suggest that the Golgi complex does not play an important role in the absorption of unesterified fatty acids.


2015 ◽  
Vol 237 (2) ◽  
pp. 133-139 ◽  
Author(s):  
Bitte Aspenström-Fagerlund ◽  
Jonas Tallkvist ◽  
Nils-Gunnar Ilbäck ◽  
Anders W. Glynn

1969 ◽  
Vol 97 (1) ◽  
pp. 65-69 ◽  
Author(s):  
Bud Tennant ◽  
Mario Reina-Guerra ◽  
Doris Harrold ◽  
Marvin Goldman

2019 ◽  
Vol 10 (7) ◽  
pp. 4381-4395 ◽  
Author(s):  
Yixiang Liu ◽  
Zichun Qiao ◽  
Wenqiang Liu ◽  
Zhanqun Hou ◽  
Di Zhang ◽  
...  

The oleic acid–protein delivery system can improve both the dispersibility and intestinal absorption of fucoxanthin in a hydrophilic environment.


1982 ◽  
Vol 242 (4) ◽  
pp. G326-G332 ◽  
Author(s):  
M. D. Sitrin ◽  
K. L. Pollack ◽  
M. J. Bolt ◽  
I. H. Rosenberg

We have studied the intestinal absorption of physiological amounts of vitamin D and 25-hydroxyvitamin D [25(OH)D3] in vivo from jejunal sacs in rats with thoracic and bile duct cannulas. Under all test conditions, absorption of 25(OH)D was greater than absorption of vitamin D. The majority of absorbed vitamin D and 25(OH)D was transported from the intestine in portal blood rather than lymph. When the luminal fluid contained 2.5 mM oleic acid and monoolein, the presence of taurocholate did not affect total intestinal absorption of vitamin D or 25(OH)D but increased recovery of vitamin in lymph. When luminal fat content was increased to 10 mM oleic acid and monoolein, total absorption of both vitamin D and 25(OH)D was enhanced by taurocholate. No significant metabolism of vitamin D or 25(OH)D occurred during absorption and transport in lymph. Fifty-three percent of lymph vitamin D was found in the chylomicron fraction, compared with only 13% of 25(OH)D. Inhibition of chylomicron synthesis by cycloheximide decreased vitamin D absorption by 46% but diminished 25(OH)D absorption by only 30%. These differences in behavior of vitamin D and 25(OH)D during absorption may explain the superior absorption of 25(OH)D in patients with malabsorption.


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