Oleic acid increases intestinal absorption of the BCRP/ABCG2 substrate, mitoxantrone, in mice

2015 ◽  
Vol 237 (2) ◽  
pp. 133-139 ◽  
Author(s):  
Bitte Aspenström-Fagerlund ◽  
Jonas Tallkvist ◽  
Nils-Gunnar Ilbäck ◽  
Anders W. Glynn
Keyword(s):  
Oleic Acid ◽  
Intestinal Absorption

Intestinal Absorption of Iodine131-Labeled Triolein and Oleic Acid in Normal Subjects and in Steatorrhea

1958 ◽  
Vol 34 (5) ◽  
pp. 901-909 ◽  
Author(s):  
Ervin Kaplan ◽  
Bernard D. Edidin ◽  
Robert C. Fruin ◽  
Lyle A. Baker
Keyword(s):  
Oleic Acid ◽  
Intestinal Absorption ◽  
Normal Subjects

Intestinal absorption of coprostanol (coprosterol) in the rat

1960 ◽  
Vol 199 (6) ◽  
pp. 1008-1010 ◽  
Author(s):  
C.S. Narayana Setty ◽  
A. C. Ivy
Keyword(s):  
Oleic Acid ◽  
Intestinal Absorption ◽  
Chemical Structure ◽  
Control Period ◽  
Chair Conformation ◽  
Color Reaction ◽  
Salt Mixture ◽  
Streptomycin Sulfate

A basal sterol-free diet consisting of casein, 18%; dextrin, 57%; oleic acid, 9%; U.S.P. salt mixture, 2%; yeast, 5%; and cellulose, 9%; along with 1% sulfasuxidine and 0.2% streptomycin sulfate was fed to eight rats during a control period of 12 days, the feces being collected under alcohol the last 4 days and assayed for digitonide sterol. The experiment was repeated with the addition of 28 mg of coprostanol to the diet. It was found that from 41 to 61% (average 48%) of the coprostanol was absorbed. The relation of chemical structure to the absorbability of cholesterol derivatives is discussed with the finding that all absorbable cholesterol derivatives have the ‘chair’ conformation, but are not alike in digitonide formation and Liebermann-Burchard color reaction.

Effect of soy protein and casein intake on intestinal absorption and lymphatic transport of cholesterol and oleic acid

1984 ◽  
Vol 40 (6) ◽  
pp. 1156-1164 ◽  
Author(s):  
G V Vahouny ◽  
W Chalcarz ◽  
S Satchithanandam ◽  
I Adamson ◽  
D M Klurfeld ◽  
...  
Keyword(s):  
Oleic Acid ◽  
Intestinal Absorption ◽  
Soy Protein ◽  
Lymphatic Transport

Influence of Microorganisms on Intestinal Absorption: Oleic Acid 131I and Triolein 131I Absorption by Germfree and Conventionalized Rats

1969 ◽  
Vol 97 (1) ◽  
pp. 65-69 ◽  
Author(s):  
Bud Tennant ◽  
Mario Reina-Guerra ◽  
Doris Harrold ◽  
Marvin Goldman
Keyword(s):  
Oleic Acid ◽  
Intestinal Absorption

Oleic acid as a protein ligand improving intestinal absorption and ocular benefit of fucoxanthin in water through protein-based encapsulation

2019 ◽  
Vol 10 (7) ◽  
pp. 4381-4395 ◽  
Author(s):  
Yixiang Liu ◽  
Zichun Qiao ◽  
Wenqiang Liu ◽  
Zhanqun Hou ◽  
Di Zhang ◽  
...  
Keyword(s):  
Oleic Acid ◽  
Intestinal Absorption ◽  
Delivery System ◽  
Protein Delivery ◽  
Acid Protein

The oleic acid–protein delivery system can improve both the dispersibility and intestinal absorption of fucoxanthin in a hydrophilic environment.

Comparison of vitamin D and 25-hydroxyvitamin D absorption in the rat

1982 ◽  
Vol 242 (4) ◽  
pp. G326-G332 ◽  
Author(s):  
M. D. Sitrin ◽  
K. L. Pollack ◽  
M. J. Bolt ◽  
I. H. Rosenberg
Keyword(s):  
Vitamin D ◽  
Oleic Acid ◽  
Bile Duct ◽  
Intestinal Absorption ◽  
Fat Content ◽  
Total Absorption ◽  
Hydroxyvitamin D ◽  
Test Conditions ◽  
25 Hydroxyvitamin D

We have studied the intestinal absorption of physiological amounts of vitamin D and 25-hydroxyvitamin D [25(OH)D3] in vivo from jejunal sacs in rats with thoracic and bile duct cannulas. Under all test conditions, absorption of 25(OH)D was greater than absorption of vitamin D. The majority of absorbed vitamin D and 25(OH)D was transported from the intestine in portal blood rather than lymph. When the luminal fluid contained 2.5 mM oleic acid and monoolein, the presence of taurocholate did not affect total intestinal absorption of vitamin D or 25(OH)D but increased recovery of vitamin in lymph. When luminal fat content was increased to 10 mM oleic acid and monoolein, total absorption of both vitamin D and 25(OH)D was enhanced by taurocholate. No significant metabolism of vitamin D or 25(OH)D occurred during absorption and transport in lymph. Fifty-three percent of lymph vitamin D was found in the chylomicron fraction, compared with only 13% of 25(OH)D. Inhibition of chylomicron synthesis by cycloheximide decreased vitamin D absorption by 46% but diminished 25(OH)D absorption by only 30%. These differences in behavior of vitamin D and 25(OH)D during absorption may explain the superior absorption of 25(OH)D in patients with malabsorption.

Inhibitory effect of gymnemic acid on intestinal absorption of oleic acid in rats

1998 ◽  
Vol 76 (10-11) ◽  
pp. 1017-1023 ◽  
Author(s):  
L F Wang ◽  
H Luo ◽  
M Miyoshi ◽  
T Imoto ◽  
Y Hiji ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Oleic Acid ◽  
Intestinal Absorption ◽  
Inhibitory Effect ◽  
Glucose Absorption ◽  
Gymnema Sylvestre ◽  
Gymnemic Acid ◽  
Acid Absorption ◽  
New Findings ◽  
Dose Dependent

Gymnemic acid, a mixture of triterpene glycosides extracted from the leaves of Gymnema sylvestre, is known to inhibit the intestinal absorption of glucose in human and rats. This work examined the effect of gymnemic acid on oleic acid absorption by the method of intestinal perfusion in rats. The results showed the following. (i) Gymnemic acid potently inhibited the absorption of oleic acid in intestine. (ii) This inhibition was dose dependent and reversible. (iii) The extent of inhibition and the recovery progress were extremely similar to that of glucose absorption. (iv) Taurocholate did not affect the inhibitory effect of gymnemic acid on oleic acid absorption, but lowering its concentration facilitated the recovery from the inhibition. (v) The absorption of oleic acid was not affected by other glycosides such as phloridzin, stevioside, and glycyrrhizin. These new findings are important for understanding the roles of gymnemic acid in therapy of diabetes mellitus and obesity.Key words: gymnemic acid, oleic acid, glucose, intestinal absorption, rat.

Increased intestinal absorption of oleic acid with aging in the rat

1983 ◽  
Vol 18 (4) ◽  
pp. 287-292 ◽  
Author(s):  
Daniel Hollander ◽  
Violetta D. Dadufalza
Keyword(s):  
Oleic Acid ◽  
Intestinal Absorption
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