scholarly journals MicroRNA‐125b in vascular diseases: An updated systematic review of pathogenetic implications and clinical applications

2019 ◽  
Vol 23 (9) ◽  
pp. 5884-5894 ◽  
Author(s):  
Chia‐Ter Chao ◽  
Hsiang‐Yuan Yeh ◽  
Tzu‐Hang Yuan ◽  
Chih‐Kang Chiang ◽  
Huei‐Wen Chen
Sensors ◽  
2021 ◽  
Vol 21 (8) ◽  
pp. 2727
Author(s):  
Hari Prasanth ◽  
Miroslav Caban ◽  
Urs Keller ◽  
Grégoire Courtine ◽  
Auke Ijspeert ◽  
...  

Gait analysis has traditionally been carried out in a laboratory environment using expensive equipment, but, recently, reliable, affordable, and wearable sensors have enabled integration into clinical applications as well as use during activities of daily living. Real-time gait analysis is key to the development of gait rehabilitation techniques and assistive devices such as neuroprostheses. This article presents a systematic review of wearable sensors and techniques used in real-time gait analysis, and their application to pathological gait. From four major scientific databases, we identified 1262 articles of which 113 were analyzed in full-text. We found that heel strike and toe off are the most sought-after gait events. Inertial measurement units (IMU) are the most widely used wearable sensors and the shank and foot are the preferred placements. Insole pressure sensors are the most common sensors for ground-truth validation for IMU-based gait detection. Rule-based techniques relying on threshold or peak detection are the most widely used gait detection method. The heterogeneity of evaluation criteria prevented quantitative performance comparison of all methods. Although most studies predicted that the proposed methods would work on pathological gait, less than one third were validated on such data. Clinical applications of gait detection algorithms were considered, and we recommend a combination of IMU and rule-based methods as an optimal solution.


2020 ◽  
Vol 45 (3) ◽  
pp. 214-218
Author(s):  
W Michael Hooten ◽  
Rajat N Moman ◽  
Jodie Dvorkin ◽  
E Morgan Pollard ◽  
Robalee Wonderman ◽  
...  

BackgroundSmoking adversely impacts pain-related outcomes of spinal cord stimulation (SCS). However, the proportion of SCS patients at risk of worse outcomes is limited by an incomplete knowledge of smoking prevalence in this population. Thus, the primary aim of this systematic review is to determine the prevalence of smoking in adults with chronic pain treated with SCS.MethodsA comprehensive search of databases from 1 January 1980 to 3 January 2019 was conducted. Eligible study designs included (1) randomized trials; (2) prospective and retrospective cohort studies; and (3) cross-sectional studies. The risk of bias was assessed using a tool specifically developed for prevalence studies. A total of 1619 records were screened, 19 studies met inclusion criteria, and the total number of participants was 10 838.ResultsThirteen studies had low or moderate risk of bias, and six had a high risk of bias. All 19 studies reported smoking status and the pooled prevalence was 38% (95% CI 30% to 47%). The pooled prevalence in 6 studies of peripheral vascular diseases was 56% (95% CI 42% to 69%), the pooled prevalence of smoking in 11 studies of lumbar spine diagnoses was 28% (95% CI 20% to 36%) and the pooled prevalence in 2 studies of refractory angina was 44% (95% CI 31% to 58%).ConclusionsThe estimated prevalence of smoking in SCS patients is 2.5 times greater than the general population. Future research should focus on development, testing and deployment of tailored smoking cessation treatments for SCS patients.


2007 ◽  
Vol 6 (4) ◽  
pp. 397-406 ◽  
Author(s):  
Luca Testa ◽  
Ravinai Bhindi ◽  
Pierfrancesco Agostoni ◽  
Antonio Abbate ◽  
Guiseppe GL Biondi Zoccai ◽  
...  

2018 ◽  
Vol 52 (16) ◽  
pp. 1022-1023
Author(s):  
Igor Tak ◽  
David Pope ◽  
Leonie Engelaar ◽  
Vincent Gouttebarge ◽  
Maarten Barendrecht ◽  
...  

2014 ◽  
Vol 112 (2) ◽  
pp. 122-135 ◽  
Author(s):  
Jia Jun Zhu ◽  
Alexander T.H. Tang ◽  
Jukka P. Matinlinna ◽  
Urban Hägg

2017 ◽  
Vol 23 (1) ◽  
Author(s):  
Hugo Gravel ◽  
Vincent Jacquemet ◽  
Nagib Dahdah ◽  
Daniel Curnier

SICOT-J ◽  
2017 ◽  
Vol 3 ◽  
pp. 17 ◽  
Author(s):  
Mohamed A. Imam ◽  
Samer S.S. Mahmoud ◽  
James Holton ◽  
Dalia Abouelmaati ◽  
Yasser Elsherbini ◽  
...  

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