scholarly journals Life span variation in 13 Drosophila species: a comparative study on life span, environmental variables and stress resistance

2015 ◽  
Vol 28 (10) ◽  
pp. 1892-1900 ◽  
Author(s):  
J. Wit ◽  
V. Loeschcke ◽  
V. Kellermann
Genetics ◽  
2003 ◽  
Vol 163 (1) ◽  
pp. 35-46 ◽  
Author(s):  
Paola Fabrizio ◽  
Lee-Loung Liou ◽  
Vanessa N Moy ◽  
Alberto Diaspro ◽  
Joan Selverstone Valentine ◽  
...  

Abstract Signal transduction pathways inactivated during periods of starvation are implicated in the regulation of longevity in organisms ranging from yeast to mammals, but the mechanisms responsible for life-span extension are poorly understood. Chronological life-span extension in S. cerevisiae cyr1 and sch9 mutants is mediated by the stress-resistance proteins Msn2/Msn4 and Rim15. Here we show that mitochondrial superoxide dismutase (Sod2) is required for survival extension in yeast. Deletion of SOD2 abolishes life-span extension in sch9Δ mutants and decreases survival in cyr1:mTn mutants. The overexpression of Sods—mitochondrial Sod2 and cytosolic CuZnSod (Sod1)—delays the age-dependent reversible inactivation of mitochondrial aconitase, a superoxide-sensitive enzyme, and extends survival by 30%. Deletion of the RAS2 gene, which functions upstream of CYR1, also doubles the mean life span by a mechanism that requires Msn2/4 and Sod2. These findings link mutations that extend chronological life span in S. cerevisiae to superoxide dismutases and suggest that the induction of other stress-resistance genes regulated by Msn2/4 and Rim15 is required for maximum longevity extension.


1984 ◽  
Vol 65 (1) ◽  
pp. 1-15 ◽  
Author(s):  
C.F. Ardavin ◽  
R.P. Gomariz ◽  
M.G. Barrutia ◽  
J. Fonfria ◽  
A. Zapata

2021 ◽  
Vol 28 ◽  
pp. 19-23
Author(s):  
O. V. Gorenskaya ◽  
V. V. Navrotskaya ◽  
N. Ye. Volkova ◽  
N. S. Filiponenko

Aim. To compare reproductive indices and stress resistance of Drosophila at outbreeding and inbreeding. Methods. Drosophila melanogaster congenic strains with incomplete development of the radial wing vein – radius incompletus – were used: the laboratory one and the strain, in which the mutation was placed into the genetic background of wild type strain, which originates from the natural population from radiation contaminated territory. Before the experiment strains have passed 65 generations of inbreeding. Viability (number of individuals, pupa stage mortality), dominant lethal mutations frequency and life span of imago at starvation were analysed. Results. After inbreeding, there was a decrease in the frequency of dominant lethal mutations and an increase in viability of the strain, which originates from the natural population, and a decrease of mortality at the pupal stage in both strains. Decreased life span of imago at starvation has been shown only for the inbred strain, which originates from the natural population. Conclusions. Inbreeding for 65 generations has no significant negative effect on reproductive indices; reduction of stress resistance during inbreeding has been shown only for the strain, which originates from the radiation contaminated territory. Keywords: Drosophila, viability, dominant lethal mutations, life span of imago at starvation, inbreeding.


2021 ◽  
Vol 52 (3) ◽  
pp. 763-773
Author(s):  
N. A. Al-Harbi

This study was aimed to investigate weeds kind in palm plantations. Date palm is the most chief economic crop in most countries of the Arabian Peninsula. Many factors, such as the presence of weeds, may cause a huge loss in the production of dates. Despite the severe damage caused by the presence of some weeds in agroecosystems, many weeds have many medicinal and economic uses. A total of 62 species were listed in palm Plantations in Tabuk and Al-Qassim Regions. A total of 51 species were listed in Tabuk Region (The number of unique species in the Tabuk Region reached 32 that not recorded in Al-Qassim Region. Also, 19 species were recorded in both of Tabuk and Al-Qassim Regions). A total of 30 weeds were listed in Al-Qassim Region (The number of unique species in the Al-Qassim Region reached 11 that not recorded in the Tabuk Region. In addition to, 19 species were recorded in both of Tabuk and Al-Qassim Regions). Zygophyllaceae was the most common family, the majority life span was annuals and the most common life form was therophyte in both Tabuk and Al-Qassim Regions. Data management and classification were achieved using PCORD (TWINSPAN and DCA analyses).


1985 ◽  
Vol 36 (5) ◽  
pp. 717 ◽  
Author(s):  
C Yule

The life cycles of six species of Dinotoperla were studied. One of these, D. bassae, only occurred in temporary pools; three species, D. thwaitesi, D. fontana and D. brevipennis, were found in intermittently flowing creeks; and these three species as well as D. eucumbene and D. christinae inhabited cool, permanent rivers. All the species were univoltine (except for D. eucumbene, which had a nymphal life span of 11-15 months). D. bassae, D. brevipennis, D. christinae and D. eucumbene had seasonal well-synchronized life cycles, although in times of severe drought the eggs of D. bassae may remain in diapause for 18 months or more. Emergence periods of all species were relatively restricted and were completed by early summer.


Antioxidants ◽  
2018 ◽  
Vol 7 (12) ◽  
pp. 192 ◽  
Author(s):  
Christina Saier ◽  
Inge Gommlich ◽  
Volker Hiemann ◽  
Sabrina Baier ◽  
Karoline Koch ◽  
...  

Agrimonia procera is a pharmacologically interesting plant which is proposed to protect against various diseases due to its high amount of phytochemicals, e.g., polyphenols. However, in spite of the amount of postulated health benefits, studies concerning the mechanistic effects of Agrimonia procera are limited. Using the nematode Caenorhabditis elegans, we were able to show that an ethanol extract of Agrimonia procera herba (eAE) mediates strong antioxidative effects in the nematode: Beside a strong radical-scavenging activity, eAE reduces accumulation of reactive oxygen species (ROS) accumulation and protects against paraquat-induced oxidative stress. The extract does not protect against amyloid-β-mediated toxicity, but efficiently increases the life span (up to 12.7%), as well as the resistance to thermal stress (prolongation of survival up to 22%), of this model organism. Using nematodes deficient in the forkhead box O (FoxO)-orthologue DAF-16, we were able to demonstrate that beneficial effects of eAE on stress resistance and life span were mediated via this transcription factor. We showed antioxidative, stress-reducing, and life-prolonging effects of eAE in vivo and were able to demonstrate a molecular mechanism of this extract. These results may be important for identifying further molecular targets of eAE in humans.


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