The influence of the renewal or the single application of the peroxide gel on the efficacy and tooth sensitivity outcomes of in‐office bleaching—A systematic review and meta‐analysis

2021 ◽  
Author(s):  
Matheus Kury ◽  
Rodrigo Barros Esteves Lins ◽  
Bruna de Almeida Resende ◽  
Mayara Zaghi Dal Picolo ◽  
Carolina Bosso André ◽  
...  
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Single Application ◽  
Tooth Sensitivity

The effects of light on bleaching and tooth sensitivity during in-office vital bleaching: A systematic review and meta-analysis

2012 ◽  
Vol 40 (8) ◽  
pp. 644-653 ◽  
Author(s):  
Li-Bang He ◽  
Mei-Ying Shao ◽  
Ke Tan ◽  
Xin Xu ◽  
Ji-Yao Li
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Tooth Sensitivity

Effect of Analgesic Drugs on Tooth Sensitivity Induced by In-office Dental Bleaching: A Systematic Review and Meta-analysis

2020 ◽  
Vol 45 (2) ◽  
pp. E66-E76 ◽  
Author(s):  
RTF Costa ◽  
SLD Moraes ◽  
CAA Lemos ◽  
JR SoutoMaior ◽  
BC do E Vasconcelos ◽  
...  
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Drug Group ◽  
Preemptive Analgesia ◽  
Tooth Bleaching ◽  
Tooth Sensitivity ◽  
Time Points ◽  
Significant Difference ◽  
Anti Inflammatory ◽  
Time Point

SUMMARY Objective: This systematic review evaluates the effect of preemptive analgesia on tooth sensitivity induced by in-office tooth bleaching. Methods: The review was structured based on the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) checklist. The methods were recorded at PROSPERO (CRD42018095440). Randomized clinical trials, studies published in English, and studies in which the efficacy of preemptive analgesia with analgesic and anti-inflammatory medications prior to in-office tooth bleaching was compared with that of placebo were included. PubMed/MEDLINE, Scopus, Web of Science, and Cochrane Library were used for searching. The electronic search provided 373 articles, and seven of them were selected based on the inclusion criteria. Results: Immediately after time point, a significant reduction of dental sensitivity was observed in the drug group compared to the control group (p=0.02; mean difference [MD]: −0.90; confidence interval [CI]: −1.63 to −0.16), while there was no significant difference at up to one-hour (p=0.22; MD: −0.42; CI: −1.09 to −0.25), at 1-24–hour (p=0.88; MD: −0.05; CI: −0.61 to 0.72), or 24-48–hour (p=0.69; MD: 0.05; CI: −0.21 to 0.32) time points. The incidence of sensitivity during the procedure was not statistically different between the groups (p=0.64; MD: 0.91; CI: 0.92 to 1.15). The nonsteroidal anti-inflammatory drug group showed a statistically significant reduction (p=0.04; MD: −0.69; CI: −1.36 to −0.03) in tooth sensitivity compared with the other groups. Conclusions: This systematic review and meta-analysis demonstrated that the medications analyzed did not interfere with the incidence of sensitivity symptoms. Regarding the intensity, no difference was observed between the drug and placebo groups at the up to one-hour, 1-24–hour, or 24-48–hour time points, and there was a statistically significant difference at the zero-hour time point in favor of the drug group. However, based on the variables that influenced this result, it should be considered with prudence because a small difference was observed.

scholarly journals Single application of topical doxycycline in management of recurrent aphthous stomatitis: a systematic review and meta-analysis of the available evidence

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Sadeq Ali Al-Maweri ◽  
Esam Halboub ◽  
Sajna Ashraf ◽  
Ahmed Y. Alqutaibi ◽  
Nashwan Mohammed Qaid ◽  
...  
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Recurrent Aphthous Stomatitis ◽  
Aphthous Stomatitis ◽  
Single Application

Tooth Sensitivity After Dental Bleaching With a Desensitizer-containing and a Desensitizer-free Bleaching Gel: A Systematic Review and Meta-analysis

2019 ◽  
Vol 44 (2) ◽  
pp. E58-E74 ◽  
Author(s):  
M Rezende ◽  
FM Coppla ◽  
K Chemin ◽  
AC Chibinski ◽  
AD Loguercio ◽  
...  
Keyword(s):  
Systematic Review ◽  
Latin American ◽  
Risk Ratio ◽  
Color Change ◽  
Meta Analysis ◽  
Cochrane Library ◽  
Tooth Sensitivity ◽  
Dental Bleaching ◽  
Gingival Irritation

SUMMARY Objectives: A systematic review and meta-analysis were performed to evaluate the risk and intensity of tooth sensitivity (TS) after dental bleaching with a desensitizer-containing and a desensitizer-free bleaching gel in adult patients. Color change and risk of gingival sensitivity was also evaluated. Methods: A comprehensive search was performed MEDLINE via PubMed, Scopus, Web of Science, Latin American and Caribbean Health Sciences Literature database (LILACS), Brazilian Library in Dentistry (BBO), EMBASE and Cochrane Library, and System for Information on Grey Literature in Europe (SIGLE) without restrictions to identify randomized clinical trials. Abstracts from the annual conference of the International Association for Dental Research (1990–2016), unpublished and ongoing trials registries, dissertations, and theses were also searched. The quality of the evidence was rated using the Grading of Recommendations: Assessment, Development and Evaluation (GRADE) approach. Data: After duplicates were removed, 1352 articles were identified. After title and abstract screening, only 47 studies remained for qualitative evaluation. Most of the studies had unclear risk of bias. No difference between groups were observed for the risk ratio of TS (risk ratio = 0.99; 95% confidence interval [CI] = 0.74–1.33); intensity of TS (standardized difference in means [SMD] = 0.04; 95% CI = 0.79–0.70); color change in shade guide units (SMD – 0.04; 95% CI = 0.50–0.42); color change in ΔE* (SMD = 0.41 (95% CI = 0.07–0.89); and risk ratio of gingival irritation (SMD = 1.05; 95% CI = 0.81–1.36). Except for the risk of TS, graded as moderate quality of evidence, all other outcomes were rated as low and very low quality. Conclusions: Incorporating desensitizers in the bleaching gel did not reduce the risk of TS, and the quality of this evidence was considered moderate. On the other hand, the intensity of TS, color change, and risk of gingival irritation was similar between groups, but the quality of the evidence for these outcomes was graded as low or very low, thus reducing the level of confidence in these outcomes.

scholarly journals At-home vs In-office Bleaching: A Systematic Review and Meta-analysis

2016 ◽  
Vol 41 (4) ◽  
pp. 341-356 ◽  
Author(s):  
JL de Geus ◽  
LM Wambier ◽  
S Kossatz ◽  
AD Loguercio ◽  
A Reis
Keyword(s):  
Systematic Review ◽  
Latin American ◽  
Meta Analysis ◽  
Adult Patients ◽  
Cochrane Library ◽  
Annual Conference ◽  
Tooth Sensitivity ◽  
Dental Bleaching ◽  
Significant Difference ◽  
At Home

SUMMARY Objective: A systematic review and meta-analysis were performed to evaluate the risk and intensity of tooth sensitivity during in-office and at-home bleaching in adult patients. The efficacy of dental bleaching was also evaluated. Methods: A comprehensive search was performed in the MEDLINE via PubMed, Scopus, Web of Science, Latin American and Caribbean Health Sciences Literature database, Brazilian Library in Dentistry, Cochrane Library, and System for Information on Grey Literature in Europe without restrictions. The annual conference of the International Association for Dental Research abstracts (1990-2014) and unpublished and ongoing trials registry were also searched. Dissertations and theses were searched using the ProQuest Dissertations and Periódicos Capes Theses databases. Only randomized clinical trials that compared the prevalence or intensity of tooth sensitivity during in-office and at-home bleaching in adult patients were included and studies that evaluated the efficacy of these dental bleaching techniques, in terms of shade guide units (ΔSGU) and in terms of color difference measured with a spectrophotometer (ΔE*). Results: After the removal of duplicates, 1139 articles were identified. After title and abstract screening, 29 studies remained. Fifteen studies were further excluded, whereas 12 studies remained for qualitative analyses and 8 for the meta-analysis of the primary and secondary outcomes. No significant difference in the risk/intensity of tooth sensitivity or in bleaching efficacy was observed in the present study. Conclusion: In an overall comparison of at-home and in-office bleaching, no differences were detected, either regarding risk/intensity of tooth sensitivity or the effectiveness of the bleaching treatment. This comparison, however, does not take into consideration variations in the protocols (daily usage time, number of bleaching sessions, and product concentration) of the bleaching techniques in the studies included.

Effect of Bleaching Gel Concentration on Tooth Color and Sensitivity: A Systematic Review and Meta-analysis

2020 ◽  
Vol 45 (3) ◽  
pp. 265-275 ◽  
Author(s):  
MMA Pontes ◽  
JML Gomes ◽  
CAA Lemos ◽  
RS Leão ◽  
SLD Moraes ◽  
...  
Keyword(s):  
Systematic Review ◽  
Hydrogen Peroxide ◽  
Systematic Reviews ◽  
Color Change ◽  
Meta Analysis ◽  
Cochrane Library ◽  
High Concentration ◽  
Tooth Sensitivity ◽  
Bleaching Procedure ◽  
Significant Difference

SUMMARY Objective: The aim of this systematic review and meta-analysis was to evaluate a high concentration of hydrogen peroxide (35%) regarding tooth sensitivity and color change in tooth bleaching in comparison to low concentrations (6% to 20%). Methods and Materials: This review was conducted using the criteria of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses and is registered on the Prospective Register of Systematic Reviews (CRD42017064493). The PICO question was “Does a concentration of hydrogen peroxide ≥35% using in-office bleaching procedure contribute to greater tooth sensitivity?” A search was made in PubMed/MEDLINE, Scopus, and the Cochrane Library. Results: Fourteen studies were selected for the qualitative analysis and seven for quantitative analysis. A total of 649 patients were evaluated (mean age: 36.32 years; range: 13.9 to 31 years), and the follow-up period ranged from one week to 12 months. The meta-analysis demonstrated that tooth sensitivity was higher in the patients submitted to treatment involving a high concentration of hydrogen peroxide (0.67; 95% confidence interval [CI]: 0.44 to 1.03; p=0.04; I2: 56%), and a significant difference was found regarding objective color ΔE (1.53; 95% CI: 2.99 to 0.08; p<0.0001; I2: 82%) but no significant difference was found regarding subjective color ΔSGU (0.24; CI: 0.75 to 1.23; p<0.00001; I2: 89%). Conclusions: This study indicated that a lower concentration of hydrogen peroxide causes less tooth sensitivity and better effectiveness in objective color change (ΔE); however, there is no difference between them related to subjective color (ΔSGU).

The effects of low-ratio n-6/n-3 PUFA on biomarkers of inflammation: a systematic review and meta-analysis

2021 ◽  
Author(s):  
Yali Wei ◽  
Yan Meng ◽  
Na Li ◽  
Qian Wang ◽  
Liyong Chen
Keyword(s):  
Systematic Review ◽  
Fatty Acid ◽  
Polyunsaturated Fatty Acid ◽  
Meta Analysis ◽  
Chain Polyunsaturated Fatty Acid ◽  
Inflammation Markers ◽  
Pufa Supplementation ◽  
Long Chain

The purpose of the systematic review and meta-analysis was to determine if low-ratio n-6/n-3 long-chain polyunsaturated fatty acid (PUFA) supplementation affects serum inflammation markers based on current studies.

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