Guanosine protects C6 astroglial cells against azide-induced oxidative damage: a putative role of heme oxygenase 1

2014 ◽  
Vol 130 (1) ◽  
pp. 61-74 ◽  
Author(s):  
André Quincozes-Santos ◽  
Larissa Daniele Bobermin ◽  
Débora Guerini Souza ◽  
Bruna Bellaver ◽  
Carlos-Alberto Gonçalves ◽  
...  
Keyword(s):  
Oxidative Damage ◽  
Heme Oxygenase ◽  
Heme Oxygenase 1 ◽  
Astroglial Cells ◽  
Putative Role ◽  
C6 Astroglial Cells

Propofol Inhibits Caspase-3 in Astroglial Cells: Role of Heme Oxygenase-1

2005 ◽  
Vol 2 (2) ◽  
pp. 141-148 ◽  
Author(s):  
Rosaria Acquaviva ◽  
Agata Campisi ◽  
Giuseppina Raciti ◽  
Roberto Avola ◽  
Maria Barcellona ◽  
...  
Keyword(s):  
Heme Oxygenase ◽  
Caspase 3 ◽  
Heme Oxygenase 1 ◽  
Astroglial Cells

Resveratrol modulates GSH system in C6 astroglial cells through heme oxygenase 1 pathway

2017 ◽  
Vol 428 (1-2) ◽  
pp. 67-77 ◽  
Author(s):  
Bernardo Assein Arús ◽  
Débora Guerini Souza ◽  
Bruna Bellaver ◽  
Diogo Onofre Souza ◽  
Carlos-Alberto Gonçalves ◽  
...  
Keyword(s):  
Heme Oxygenase ◽  
Heme Oxygenase 1 ◽  
Astroglial Cells ◽  
C6 Astroglial Cells

Heme oxygenase-1 mediates the protective role of quercetin against ethanol-induced rat hepatocytes oxidative damage

2012 ◽  
Vol 26 (1) ◽  
pp. 74-80 ◽  
Author(s):  
Shuang Liu ◽  
Wei Hou ◽  
Ping Yao ◽  
Na Li ◽  
Biyun Zhang ◽  
...  
Keyword(s):  
Oxidative Damage ◽  
Heme Oxygenase ◽  
Rat Hepatocytes ◽  
Protective Role ◽  
Heme Oxygenase 1

scholarly journals Lipoic acid and N-acetylcysteine prevent ammonia-induced inflammatory response in C6 astroglial cells: The putative role of ERK and HO1 signaling pathways

2015 ◽  
Vol 29 (7) ◽  
pp. 1350-1357 ◽  
Author(s):  
Camila Leite Santos ◽  
Larissa Daniele Bobermin ◽  
Débora Guerini Souza ◽  
Bruna Bellaver ◽  
Gabriela Bellaver ◽  
...  
Keyword(s):  
Inflammatory Response ◽  
Signaling Pathways ◽  
Lipoic Acid ◽  
Astroglial Cells ◽  
Putative Role ◽  
C6 Astroglial Cells

Involvement of Heme Oxygenase-1 in Neuropsychiatric and Neurodegenerative Diseases

2018 ◽  
Vol 24 (20) ◽  
pp. 2283-2302 ◽  
Author(s):  
Vivian B. Neis ◽  
Priscila B. Rosa ◽  
Morgana Moretti ◽  
Ana Lucia S. Rodrigues
Keyword(s):  
Neurodegenerative Diseases ◽  
Heme Oxygenase ◽  
Therapeutic Potential ◽  
Redox Homeostasis ◽  
Antioxidant Defenses ◽  
Heme Oxygenase 1 ◽  
Physiological Conditions ◽  
And Oxidative Stress ◽  
Defensive Mechanism

Heme oxygenase (HO) family catalyzes the conversion of heme into free iron, carbon monoxide and biliverdin. It possesses two well-characterized isoforms: HO-1 and HO-2. Under brain physiological conditions, the expression of HO-2 is constitutive, abundant and ubiquitous, whereas HO-1 mRNA and protein are restricted to small populations of neurons and neuroglia. HO-1 is an inducible enzyme that has been shown to participate as an essential defensive mechanism for neurons exposed to oxidant challenges, being related to antioxidant defenses in certain neuropathological conditions. Considering that neurodegenerative diseases (Alzheimer’s Disease (AD), Parkinson’s Disease (PD) and Multiple Sclerosis (MS)) and neuropsychiatric disorders (depression, anxiety, Bipolar Disorder (BD) and schizophrenia) are associated with increased inflammatory markers, impaired redox homeostasis and oxidative stress, conditions that may be associated with alterations in HO-levels/activity, the purpose of this review is to present evidence on the possible role of HO-1 in these Central Nervous System (CNS) diseases. In addition, the possible therapeutic potential of targeting brain HO-1 is explored in this review.

The Role of Statins in the Activation of Heme Oxygenase-1 in Cardiovascular Diseases

2017 ◽  
Vol 18 (6) ◽  
pp. 674-686 ◽  
Author(s):  
Aleksandra Piechota-Polanczyk ◽  
Alicja Jozkowicz
Keyword(s):  
Cardiovascular Diseases ◽  
Heme Oxygenase ◽  
Heme Oxygenase 1

scholarly journals Potential role of heme oxygenase-1 in the progression of rat adjuvant arthritis

2004 ◽  
Vol 85 (1) ◽  
pp. 34-44 ◽  
Author(s):  
Isabel Devesa ◽  
Maria Luisa Ferrándiz ◽  
Isabel Guillén ◽  
José Miguel Cerdá ◽  
Maria José Alcaraz
Keyword(s):  
Heme Oxygenase ◽  
Adjuvant Arthritis ◽  
Potential Role ◽  
Heme Oxygenase 1 ◽  
Rat Adjuvant Arthritis
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