scholarly journals Quantification of Optic Nerve and Sheath Diameter by Transorbital Sonography: A Systematic Review and Metanalysis

2020 ◽  
Vol 30 (2) ◽  
pp. 165-174 ◽  
Author(s):  
Christoph Schroeder ◽  
Aristeidis H. Katsanos ◽  
Daniel Richter ◽  
Georgios Tsivgoulis ◽  
Ralf Gold ◽  
...  
Biomedika ◽  
2019 ◽  
Vol 11 (2) ◽  
pp. 96-104
Author(s):  
Sulistyani Sulistyani ◽  
Rivan Danuaji

Nyeri kepala merupakan penanda adanya gangguan intrakranial. Nervus optikus merupakan saraf kranialis yang mudah dipengaruhi langsung adanya gangguan intrakranial. Kalimatnya Jumping. Kelainan nervus optikus dapat diketahui dengan adanya pelebaran optic nerve sheath diameter (ONSD). ONSD dapat diukur dengan transorbital sonografi yang bersifat nonimvasif. Penelitian ini bertujuan membedakan diameter ONSD pada orang yang nyeri kepala dan orang normal. Penelitian ini menggunakan pendekatan observasional analitik dengan metode cross sectional. Responden diambil dari pasien rawat inap dan responden normal. Hasil penelitian didapatkan rata – rata nilai ONSD pada pasien nyeri kepala adalah 0,52 ± 0,86 dan pada responden normal adalah 0,40 ± 0,57 (p < 0,05). Terdapat perbedaan signifikan nilai ONSD pada pasien normal dan nyeri kepala. Penelitian ini membuktikan bahwa terdapat gangguan intrakranial pada orang dengan nyeri kepala dan dapat digunakan sebagai deteksi dini.Kata Kunci: Optic Nerve Sheath Diameter (ONSD), Responden Normal, Nyeri KepalaHeadache is a sign of intracranial disorders. The optic nerve is a cranial nerve that is easily affected directly by intracranial disorders. The sentence is Jumping. Optic nerve abnormalities can be identified by the widening of the optic nerve sheath diameter (ONSD). ONSD can be measured by transorbital sonography which is nonimvasive. This study aims to distinguish the ONSD diameter in people with headaches and normal people. This research uses an analytic observational approach with cross sectional method. Respondents were taken from inpatients and normal respondents. The results showed that the average value of ONSD in headache patients was 0.52 ± 0.86 and in normal respondents was 0.40 ± 0.57 (p <0.05). There is a significant difference in the value of ONSD in normal patients and headaches. This research proves that there are intracranial disorders in people with headaches and can be used as early detection.Keyword: Optic nerve sheath diameter , headache , normal volunteer 


2020 ◽  
Vol 22 (Supplement_2) ◽  
pp. ii185-ii185
Author(s):  
Yash J Vaishnav ◽  
Raj Singh ◽  
Prabhanjan Didwania ◽  
Eric J Lehrer ◽  
Tatiana Bakaeva ◽  
...  

Abstract INTRODUCTION Optic nerve sheath meningiomas (ONSMs) are often managed with radiotherapy (RT) with the goal of achieving radiographic local control (LC) to prevent further decline in visual acuity (VA); however, reports on outcomes are limited to small retrospective series. Thus, we aimed to perform a systematic review and meta-analysis of outcomes for patients with ONSM treated with RT. METHODS A PICOS/PRISMA/MOOSE selection criteria was utilized to identify studies for inclusion. Primary outcomes were stable or improved VA and radiographic LC at last follow-up. The secondary outcome was incidence of radiation-induced retinopathy. Weighted random effects meta-analyses using the DerSimonian and Laird methods were conducted to characterize effect sizes. Mixed effects regression models were used to examine potential correlations between gross tumor volume (GTV) and outcomes. RESULTS In total, 381 patients with ONSM across 18 published studies were included. Of these, 332 and 386 treated ONSMs had information on VA or LC, respectively. Median age was 46.75 (range: 9-87), median/mean GTV was 2.905cc (range: 0.28-26.3), and median follow-up was 51.15 months (range: 1-248.4 months). The estimated LC rate at last follow-up was 100% (95% CI: 98-100%), and the estimated proportion of patients with stable or improved VA at last follow-up was 89% (95% CI: 84-93%). The rate of chronic radiation retinopathy was estimated to be 7% (95% CI: 5-11%). GTV was significantly associated with VA (p=0.014) with estimated VA rates of 96.4%, 91.4%, and 80.5% for GTVs of 2.0, 3.0, and 4.0ccs, respectively. CONCLUSIONS RT was well-tolerated in the treatment of ONSM with excellent LC achieved. Nearly 90% of patients noted either stability or improvement in VA. Larger ONSMs were found to be associated with poorer VA. Incidences of radiation-induced retinopathy were limited and estimated to be less than 10%.


2021 ◽  
Author(s):  
Visish M Srinivasan ◽  
Stefan W Koester ◽  
Michele S Wang ◽  
Redi Rahmani ◽  
Kevin L Ma ◽  
...  

Abstract BACKGROUND Although rare, cavernous malformations (CMs) of the optic nerve and anterior optic pathway (optic pathway cavernous malformations [OPCMs]) can occur, as described in several single case reports in the literature. OBJECTIVE To describe the technical aspects of microsurgical management of CMs of the optic pathway on the basis of an extensive single-center experience and review of the literature. METHODS A systematic literature review was performed to augment an earlier review, using PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. In addition, an institutional database was searched for all patients undergoing surgical resection of OPCMs. Patient information, surgical technique, and clinical and radiographic outcomes were assessed. RESULTS Since the previous report, 14 CMs were resected at this institution or by the senior author at another institution. In addition, 34 cases were identified in the literature since the systematic review in 2015, including some earlier cases that were not discussed in the previous report. Most OPCMs were resected via pterional, orbital-pterional, and orbitozygomatic craniotomies. Visual outcomes were similar to those in earlier reports, with 70% of patients reporting stable to normal vision postoperatively. CONCLUSION OPCMs can occur throughout the anterior visual pathway and may cause significant symptoms. Surgery is feasible and should be considered for OPCMs presenting to a surface of the nerve. Favorable results can be obtained with resection, although optimal results are obtained with patients who present with milder symptoms without longstanding damage to the optic apparatus.


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