Therapeutic effects of açaí seed extract on hepatic steatosis in high‐fat diet‐induced obesity in male mice: a comparative effect with rosuvastatin

2020 ◽  
Vol 72 (12) ◽  
pp. 1921-1932
Author(s):  
Thamires Barros Tavares ◽  
Izabelle Barcellos Santos ◽  
Graziele Freitas Bem ◽  
Dayane Teixeira Ognibene ◽  
Ana Paula Machado Rocha ◽  
...  
Author(s):  
Shuyi Wang ◽  
Jun Tao ◽  
Huaguo Chen ◽  
Machender R. Kandadi ◽  
Mingming Sun ◽  
...  

2021 ◽  
Author(s):  
Haizhao Song ◽  
Xinchun Shen ◽  
Yang Zhou ◽  
Xiaodong Zheng

Supplementation of black rice anthocyanins (BRAN) alleviated high fat diet-induced obesity, insulin resistance and hepatic steatosis by improvement of lipid metabolism and modification of the gut microbiota.


2020 ◽  
Vol 65 ◽  
pp. 103726 ◽  
Author(s):  
Matheus Henrique Romão ◽  
Graziele Freitas de Bem ◽  
Izabelle Barcellos Santos ◽  
Ricardo de Andrade Soares ◽  
Dayane Teixeira Ognibene ◽  
...  

2019 ◽  
Vol 59 ◽  
pp. 319-328 ◽  
Author(s):  
Paula Aranaz ◽  
David Navarro-Herrera ◽  
Ana Romo-Hualde ◽  
María Zabala ◽  
Miguel López-Yoldi ◽  
...  

2019 ◽  
Vol 12 (2) ◽  
pp. 505-516 ◽  
Author(s):  
Diana C. Castro-Rodríguez ◽  
Luis A. Reyes-Castro ◽  
Claudia C. Vega ◽  
Guadalupe L. Rodríguez-González ◽  
Jorge Yáñez-Fernández ◽  
...  

2018 ◽  
Vol 16 (1) ◽  
Author(s):  
Guangyan Wu ◽  
Mengwei Niu ◽  
Wenli Tang ◽  
Jingjuan Hu ◽  
Guoquan Wei ◽  
...  

2020 ◽  
Vol 27 (10) ◽  
pp. 2733-2746
Author(s):  
Omnia E. Kilany ◽  
Heba M.A. Abdelrazek ◽  
Tahany Saleh Aldayel ◽  
Shimaa Abdo ◽  
Manal M.A. Mahmoud

2011 ◽  
Vol 23 (7) ◽  
pp. 929 ◽  
Author(s):  
Nicole O. Palmer ◽  
Tod Fullston ◽  
Megan Mitchell ◽  
Brian P. Setchell ◽  
Michelle Lane

Male obesity is associated with reduced sperm function and increased incidence of sperm DNA damage; however, the underlying molecular mechanisms have not yet been identified. Mammalian SIRT6 protein is involved in caloric-dependant DNA damage repair in other tissue types, yet a possible role for SIRT6 in male obesity and subfertility has not been investigated previously. To assess SIRT6 levels and activity in the testes, male mice (n = 12 per diet) were fed either a control diet (CD; 6% fat) or a high-fat diet (HFD; 21% fat) for 16 weeks before the collection of testes and spermatozoa. SIRT6 protein was localised to the nucleus of transitional spermatids and the acrosome of mature spermatozoa, with levels significantly decreased in HFD-fed male mice (P < 0.05). This decrease in SIRT6 protein was associated with transitional spermatids having increased levels of acetylated H3K9 in the nucleus (P < 0.01) and increased DNA damage (P < 0.001). We propose a role for SIRT6 in spermiogenesis and potentially protamination processes, which are known to be compromised by male obesity.


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