Effects of smoking on the gingival crevicular fluid levels of interleukin‐17A, interleukin‐17E, and oxidative stress following periodontal treatment process

Author(s):  
Muge Lütfioğlu ◽  
Umur Sakallıoğlu ◽  
Eser Elif Sakallıoğlu ◽  
Feyza O. Özden ◽  
Sebati Sinan Ürkmez ◽  
...  
2017 ◽  
Vol 68 (6) ◽  
pp. 1201-1204 ◽  
Author(s):  
Iulia Ioana Stanescu ◽  
Alexandra Totan ◽  
Florentina Rus ◽  
Daniela Miricescu ◽  
Brandusa Mocanu ◽  
...  

The past decades demonstrated that saliva and its components represent a remarkable diagnosis fluid with valuable clinical uses for both oral and systemic diseases. At the same time it is well established that oxidative stress is involved in a wide number of pathologies, including periodontitis. The specific aim of the present study which included 50 subjects is to determine if saliva can be used in clinical settings to correlate oxidative stress and tissue destruction markers with the severity of periodontal disease. An important oxidative stress marker - 8-hydroxydesoxyguanosine (8-OHdG) and a collagen degradation marker - beta-crosslaps (b-CTX) were quantified in both saliva and gingival crevicular fluid (GCF) using ELISA kits and were found to be significantly increased in the chronic periodontitis group when compared to respective controls (p[0.05). At the same time positive correlations were observed between whole saliva and gingival crevicular fluid (p[0.05). Significant correlations were also determined between GCF and salivary markers and clinical parameters of periodontal disease. Present results demonstrate that saliva and its components can successfully be used in clinical settings and represents a reliable tool for assessing periodontal disease severity.


2006 ◽  
Vol 77 (1) ◽  
pp. 67-72 ◽  
Author(s):  
Özlem Daltaban ◽  
Işıl Saygun ◽  
Belgin Bal ◽  
Köksal Baloş ◽  
Muhittin Serdar

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