scholarly journals Platelet-reactivity tests identify patients at risk of secondary cardiovascular events: a systematic review and meta-analysis

2014 ◽  
Vol 12 (5) ◽  
pp. 736-747 ◽  
Author(s):  
P. P. Wisman ◽  
M. Roest ◽  
F. W. Asselbergs ◽  
P. G. de Groot ◽  
F. L. Moll ◽  
...  
Keyword(s):  
Systematic Review ◽  
At Risk ◽  
Cardiovascular Events ◽  
Platelet Reactivity ◽  
Meta Analysis ◽  
Patients At Risk

Statin use for the prevention of seizure and epilepsy in the patients at risk: A systematic review and meta-analysis of cohort studies

2021 ◽  
pp. 106652
Author(s):  
Yu Guo ◽  
Ling-Hong Zhu ◽  
Kai Zhao ◽  
Xin-Mei Guo ◽  
Ming-Fei Yang
Keyword(s):  
Systematic Review ◽  
At Risk ◽  
Cohort Studies ◽  
Meta Analysis ◽  
Patients At Risk ◽  
Statin Use

scholarly journals A systematic review and meta-analysis on the hazards of discontinuing or not adhering to aspirin among 50 279 patients at risk for coronary artery disease

2006 ◽  
Vol 27 (22) ◽  
pp. 2667-2674 ◽  
Author(s):  
G. G.L. Biondi-Zoccai ◽  
M. Lotrionte ◽  
P. Agostoni ◽  
A. Abbate ◽  
M. Fusaro ◽  
...  
Keyword(s):  
Systematic Review ◽  
Coronary Artery Disease ◽  
At Risk ◽  
Coronary Artery ◽  
Meta Analysis ◽  
Patients At Risk ◽  
Artery Disease

scholarly journals Effectiveness of technology-based interventions in detection, prevention, monitoring and treatment of patients at risk or diagnosed with mild cognitive impairment: protocol for a systematic review

BMJ Open ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. e045978
Author(s):  
Jordi Martínez-Soldevila ◽  
Roland Pastells-Peiró ◽  
Carolina Climent-Sanz ◽  
Gerard Piñol-Ripoll ◽  
Mariona Rocaspana-García ◽  
...  
Keyword(s):  
Systematic Review ◽  
At Risk ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Cognitive Decline ◽  
Meta Analysis ◽  
Cognitive Disorders ◽  
Increased Risk ◽  
Patients At Risk ◽  
Review Protocol

IntroductionThe gradual changes over the decades in the longevity and ageing of European society as a whole can be directly related to the prolonged decline in the birth rate and increase in the life expectancy. According to the WHO, there is an increased risk of dementia or other cognitive disorders as the population ages, which have a major impact on public health. Mild cognitive impairment (MCI) is described as a greater than expected cognitive decline for an individual’s age and level of education, but that does not significantly interfere with activities of daily living. Patients with MCI exhibit a higher risk of dementia compared with others in the same age group, but without a cognitive decline, have impaired walking and a 50% greater risk of falling.The urban lifestyle and advent of smartphones, mobility and immediate access to all information via the internet, including health information, has led to a totally disruptive change in most general aspects.This systematic review protocol is aimed at evaluating the effectiveness of technology-based interventions in the detection, prevention, monitoring and treatment of patients at risk or diagnosed with MCI.Methods and analysisThis review protocol follows the recommendations of the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols reporting guidelines. The search will be performed on MEDLINE (PubMed), CENTRAL, CINAHL Plus, ISI Web of Science and Scopus databases from 2010 to 2020. Studies of interventions either randomised clinical trials or pre–post non-randomised quasi-experimental designs, published in English and Spanish will be included. Articles that provide relevant information on the use of technology and its effectiveness in interventions that assess improvements in early detection, prevention, follow-up and treatment of the patients at risk or diagnosed with MCI will be included.Ethics and disseminationEthics committee approval not required. The results will be disseminated in publications and congresses.

scholarly journals MRI T2 and T1ρ relaxation in patients at risk for knee osteoarthritis: a systematic review and meta-analysis

2019 ◽  
Vol 20 (1) ◽  
Author(s):  
Hayden F. Atkinson ◽  
Trevor B. Birmingham ◽  
Rebecca F. Moyer ◽  
Daniel Yacoub ◽  
Lauren E. Kanko ◽  
...  
Keyword(s):  
Systematic Review ◽  
At Risk ◽  
Knee Osteoarthritis ◽  
Meta Analysis ◽  
Patients At Risk

scholarly journals Use of anti-platelet agents in the prevention of hepatic fibrosis in patients at risk for chronic liver disease: a systematic review and meta-analysis

2018 ◽  
Vol 13 (1) ◽  
pp. 84-90 ◽  
Author(s):  
Umair Iqbal ◽  
Brittany B. Dennis ◽  
Andrew A. Li ◽  
George Cholankeril ◽  
Donghee Kim ◽  
...  
Keyword(s):  
Systematic Review ◽  
At Risk ◽  
Liver Disease ◽  
Chronic Liver Disease ◽  
Hepatic Fibrosis ◽  
Meta Analysis ◽  
Chronic Liver ◽  
Patients At Risk

Can we recommend mirtazapine and bupropion for patients at risk for bleeding?: A systematic review and meta-analysis

2018 ◽  
Vol 225 ◽  
pp. 221-226 ◽  
Author(s):  
Kyoung-Sae Na ◽  
Han-Yong Jung ◽  
Seong-Jin Cho ◽  
Seo-Eun Cho
Keyword(s):  
Systematic Review ◽  
At Risk ◽  
Meta Analysis ◽  
Patients At Risk ◽  
Risk For Bleeding

scholarly journals The Management of Anticoagulants in Patients With Atrial Fibrillation and History of Falls or Risk of Falls: The Liverpool Af-falls Project. Protocol for a Systematic Review and Meta-analysis

2021 ◽  
Author(s):  
Thibaut Galvain ◽  
Ruaraidh Hill ◽  
Sarah Donegan ◽  
Paulo Lisboa ◽  
Gregory Y. H. Lip ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Systematic Review ◽  
At Risk ◽  
Meta Analysis ◽  
Vitamin K Antagonist ◽  
Risk Of Bias ◽  
Safety And Efficacy ◽  
Risk Of Falls ◽  
Patients At Risk ◽  
History Of

Abstract BackgroundAtrial fibrillation affects an estimated 33 million individuals worldwide and is a major cause of stroke, heart failure, and death. Anticoagulants substantially reduces risk of stroke but are also associated with an increased risk of bleeding and especially intracranial hemorrhages which are the most feared complication. Because of this many patients are not offered anticoagulants, particularly patients at risk of falls or with history of falls. It is unclear what anticoagulant treatment these patients should be offered, and the Liverpool AF-Falls project aims to investigate this area. This protocol for a systematic review and meta-analysis aims to define what is the most appropriate anticoagulant treatment option for the for the management of atrial fibrillation patients at risk of falls or with a history of falls. MethodsThis systematic review and meta-analysis will include randomized and non-randomized studies evaluating safety and efficacy of different anticoagulant treatments (vitamin K antagonist, non-vitamin K antagonist oral anti-coagulant, anti-platelet agent and no treatment). Bibliographic databases (Cochrane Central Register of Controlled Trials, MEDLINE, Embase, Scopus, CINAHL, Web of Science and ClinicalTrials.gov) will be searched according to a pre-specified search strategy. Titles, abstracts, and full texts will be assessed by two independent reviewers and disagreement resolved with a third independent reviewer. The Cochrane Risk of Bias tool 2 will be used to assess risk of bias in randomized trials and the Newcastle-Ottawa-Scale tool will be used for non-randomized studies. Pairwise meta-analysis based on the fixed and random-effects models will be conducted. Publication bias will be evaluated with a funnel plot and the Egger’s test. Heterogeneity will be assessed with the I2 statistic. If conditions for indirect comparison are met and sufficient data are available, a network meta-analysis will be conducted using frequentist and Bayesian methodologies. DiscussionThis review will be the first to summarize direct and indirect evidence on safety and efficacy of anticoagulant treatments in atrial fibrillation patients at risk of falls or with history of falls. The findings will be important to patients, clinicians, and health policy-makers to inform best practice in the use of these treatments. Systematic review registrationPROSPERO registry number: CRD42020201086

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