scholarly journals Polymorphisms in cis ‐elements confer SAUR26 gene expression difference for thermo‐response natural variation in Arabidopsis

2020 ◽  
Author(s):  
Zhixue Wang ◽  
Leiyun Yang ◽  
Dianxing Wu ◽  
Ning Zhang ◽  
Jian Hua

IEEE Access ◽  
2019 ◽  
Vol 7 ◽  
pp. 142586-142594 ◽  
Author(s):  
Yang Jiang ◽  
Xiaoyong Pan ◽  
Yu-Hang Zhang ◽  
Tao Huang ◽  
Yufei Gao


2012 ◽  
Vol 40 (9) ◽  
pp. 3800-3811 ◽  
Author(s):  
Aradhita Baral ◽  
Pankaj Kumar ◽  
Rashi Halder ◽  
Prithvi Mani ◽  
Vinod Kumar Yadav ◽  
...  




2021 ◽  
Vol 7 (3) ◽  
pp. 42
Author(s):  
Victoria Mamontova ◽  
Barbara Trifault ◽  
Lea Boten ◽  
Kaspar Burger

Gene expression is an essential process for cellular growth, proliferation, and differentiation. The transcription of protein-coding genes and non-coding loci depends on RNA polymerases. Interestingly, numerous loci encode long non-coding (lnc)RNA transcripts that are transcribed by RNA polymerase II (RNAPII) and fine-tune the RNA metabolism. The nucleolus is a prime example of how different lncRNA species concomitantly regulate gene expression by facilitating the production and processing of ribosomal (r)RNA for ribosome biogenesis. Here, we summarise the current findings on how RNAPII influences nucleolar structure and function. We describe how RNAPII-dependent lncRNA can both promote nucleolar integrity and inhibit ribosomal (r)RNA synthesis by modulating the availability of rRNA synthesis factors in trans. Surprisingly, some lncRNA transcripts can directly originate from nucleolar loci and function in cis. The nucleolar intergenic spacer (IGS), for example, encodes nucleolar transcripts that counteract spurious rRNA synthesis in unperturbed cells. In response to DNA damage, RNAPII-dependent lncRNA originates directly at broken ribosomal (r)DNA loci and is processed into small ncRNA, possibly to modulate DNA repair. Thus, lncRNA-mediated regulation of nucleolar biology occurs by several modes of action and is more direct than anticipated, pointing to an intimate crosstalk of RNA metabolic events.



2012 ◽  
Vol 2 (12) ◽  
pp. 1643-1649 ◽  
Author(s):  
Martha H. Elmore ◽  
John G. Gibbons ◽  
Antonis Rokas


2017 ◽  
Vol 89 (4) ◽  
pp. 706-717 ◽  
Author(s):  
Amanda J. Waters ◽  
Irina Makarevitch ◽  
Jaclyn Noshay ◽  
Liana T. Burghardt ◽  
Candice N. Hirsch ◽  
...  


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