Inhibition of DNA demethylation enhances plant tolerance to cadmium toxicity by improving iron nutrition

Significant quantities of Cd have been added to soils globally due to various anthropogenic activities, posing a serious threat to safe food production and human health. Rhizosphere, as an important interface of soil and plant, plays a significant role in the agro-environmental system. This article presents a review of relationship between root excretion and microorganisms and plant resistance to Cd toxicity and possible mechanisms. Root exudates markedly altered in species and quantity under Cd stress. Root exudates can affect Cd absorption by plants through changing the physical and chemical characteristics of rhizospheres. The influence of root exudates on Cd bioavailability and toxicity may include modifying the rhizosphere pH and Eh, chelating/complexing and depositing with Cd ions, and altering the community construction, the numbers and activities of rhizospheric microbes. In this paper, the methods to reduce the transfer of Cd in soil-plant system by adjusting rhizosphere environment are discussed, and some aspects are also proposed that should be emphasized in the future research work.

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A cadmium stress-responsive gene AtFC1 confers plant tolerance to cadmium toxicity

BMC Plant Biology ◽

10.1186/s12870-017-1141-0 ◽

2017 ◽

Vol 17 (1) ◽

Cited By ~ 33

Author(s):

Jun Song ◽

Sheng Jun Feng ◽

Jian Chen ◽

Wen Ting Zhao ◽

Zhi Min Yang

Keyword(s):

Cadmium Toxicity ◽

Cadmium Stress ◽

Plant Tolerance ◽

Responsive Gene ◽

Tolerance To Cadmium

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Absence of Changes in Metallothionein RNA in the Rat Testes Made Refractory to Cadmium Toxicity by Zinc Pretreatment

Human & Experimental Toxicology ◽

10.1177/096032719401300110 ◽

1994 ◽

Vol 13 (1) ◽

pp. 65-67 ◽

Cited By ~ 12

Author(s):

Zakaria Z. Wahba ◽

Mark Steven Miller ◽

Michael P. Waalkes

Keyword(s):

Low Dose ◽

Interstitial Cell ◽

Cadmium Toxicity ◽

Cdna Probe ◽

Testicular Toxicity ◽

Slot Blot ◽

Tissue Resistance ◽

Blot Technique ◽

Induced Tolerance ◽

Tolerance To Cadmium

Testicular toxicity and interstitial cell tumours induced by cadmium are prevented by zinc or by low dose cadmium pretreatments. The mechanism of this tolerance is unknown, though metallothionein (MT) is thought to play a role in tissue resistance to cadmium toxicity. Thus, the possible involvement of the testicular MT gene in metal-induced tolerance to cadmium toxicity was studied. Rats were pretreated with zinc (1.0 mmol kg-1, s.c.). Histological examination of the testes indicated such pretreatments prevented the necrotizing effects of subsequent doses of cadmium (20 ?mol kg-1, s.c.) administered 24 h later. RNA was extracted from testes or liver 24 h after zinc pretreatment, and analysed by the slot blot technique using the p2A10 cDNA probe to the MT gene. Zinc pretreatment had little effect on MT RNA in the testes, and such pretreatments did not alter testicular cadmium-binding protein capacity. In contrast, RNAs derived from livers of zinc pretreated rats showed marked increases in MT RNA and MT protein. Hence, the testicular MT gene does not appear to play a major role in the induced tolerance to cadmium toxicity and carcinogenesis generated by zinc.

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