Brain tumor response to nimotuzumab treatment evaluated on magnetic resonance imaging

2014 ◽  
Vol 56 (1) ◽  
pp. 43-46 ◽  
Author(s):  
Evelio Rafael González Dalmau ◽  
Carlos Cabal Mirabal ◽  
Giselle Saurez Martínez ◽  
Agustín Lage Dávila ◽  
José Carlos Ugarte Suárez ◽  
...  
2021 ◽  
Vol 11 (3) ◽  
pp. 352
Author(s):  
Isselmou Abd El Kader ◽  
Guizhi Xu ◽  
Zhang Shuai ◽  
Sani Saminu ◽  
Imran Javaid ◽  
...  

The classification of brain tumors is a difficult task in the field of medical image analysis. Improving algorithms and machine learning technology helps radiologists to easily diagnose the tumor without surgical intervention. In recent years, deep learning techniques have made excellent progress in the field of medical image processing and analysis. However, there are many difficulties in classifying brain tumors using magnetic resonance imaging; first, the difficulty of brain structure and the intertwining of tissues in it; and secondly, the difficulty of classifying brain tumors due to the high density nature of the brain. We propose a differential deep convolutional neural network model (differential deep-CNN) to classify different types of brain tumor, including abnormal and normal magnetic resonance (MR) images. Using differential operators in the differential deep-CNN architecture, we derived the additional differential feature maps in the original CNN feature maps. The derivation process led to an improvement in the performance of the proposed approach in accordance with the results of the evaluation parameters used. The advantage of the differential deep-CNN model is an analysis of a pixel directional pattern of images using contrast calculations and its high ability to classify a large database of images with high accuracy and without technical problems. Therefore, the proposed approach gives an excellent overall performance. To test and train the performance of this model, we used a dataset consisting of 25,000 brain magnetic resonance imaging (MRI) images, which includes abnormal and normal images. The experimental results showed that the proposed model achieved an accuracy of 99.25%. This study demonstrates that the proposed differential deep-CNN model can be used to facilitate the automatic classification of brain tumors.


2009 ◽  
Vol 110 (4) ◽  
pp. 737-739 ◽  
Author(s):  
Joo-Hun David Eum ◽  
Astrid Jeibmann ◽  
Werner Wiesmann ◽  
Werner Paulus ◽  
Heinrich Ebel

Primary intracerebral manifestation of multiple myeloma is rare and usually arises from the meninges or brain parenchyma. The authors present a case of multiple myeloma primarily manifesting within the lateral ventricle. A 67-year-old man was admitted with headache accompanied by slowly progressing right hemiparesis. Magnetic resonance imaging showed a large homogeneous contrast-enhancing intraventricular midline mass and hydrocephalus. The tumor was completely resected, and histopathological examination revealed plasmacytoma. After postoperative radio- and chemotherapy, vertebral osteolysis was detected as a secondary manifestation of multiple myeloma.


1998 ◽  
Vol 5 (2) ◽  
pp. 115-123 ◽  
Author(s):  
Michael H. Lev ◽  
Fred Hochberg

Background: Although magnetic resonance imaging (MRI) is effective in detecting the location of intracranial tumors, new imaging techniques have been studied that may enhance the specificity for the prediction of histologic grade of tumor and for the distinction between recurrence and tumor necrosis associated with cancer therapy. Methods: The authors review their experience and that of others on the use of perfusion magnetic resonance imaging to evaluate responses of brain tumors to new therapies. Results: Functional imaging techniques that can distinguish tumor from normal brain tissue using physiological parameters. These new approaches provide maps of tumor perfusion to monitor the effects of novel compounds that restrict tumor angiogenesis. Conclusions: Perfusion MRI not only may be as effective as radionuclide-based techniques in sensitivity and specificity in assessing brain tumor responses to new therapies, but also may offer higher resolution and convenient co-registration with conventional MRI, as well as time- and cost-effectiveness. Further study is needed to determine the role of perfusion MRI in assessing brain tumor responses to new therapies.


2021 ◽  
Vol 58 (4) ◽  
pp. 0410022
Author(s):  
牟海维 Mu Haiwei ◽  
郭颖 Guo Ying ◽  
全星慧 Quan Xinghui ◽  
曹志民 Cao Zhimin ◽  
韩建 Han Jian

2019 ◽  
Vol 32 (4) ◽  
pp. 273-276 ◽  
Author(s):  
David J Ritchie ◽  
Charles Q Li ◽  
Reid Hoshide ◽  
Daniel Vinocur

Gadolinium (Gd)-enhanced magnetic resonance imaging plays an essential role in the detection, characterization, and staging of intracranial neoplasms and vascular abnormalities. Although Gd is helpful in a majority of situations, it can lead to diagnostic misinterpretation in the setting of active vascular extravasation. Scarce reports of intracranial extravasation of Gd are present in the literature. Here, we report the first case of surgically proven spontaneous intraparenchymal extravasation of Gd mimicking an enhancing intra-axial neoplasm in a pediatric patient. Early and accurate recognition of Gd extravasation is critical in obtaining the accurate diagnosis and triaging patients expeditiously into proper avenues of care.


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