scholarly journals P5‐70: Effectiveness of favipiravir in COVID‐19 patients with multiple (≥2) or less (<2) comorbidities: A real word experience from India

Respirology ◽  
2021 ◽  
Vol 26 (S3) ◽  
pp. 184-184
Keyword(s):  
2020 ◽  
Vol 51 (3) ◽  
pp. 603-616
Author(s):  
Kenn Apel ◽  
Victoria S. Henbest

Purpose Morphological awareness is the ability to consciously manipulate the smallest units of meaning in language. Morphological awareness contributes to success with literacy skills for children with typical language and those with language impairment. However, little research has focused on the morphological awareness skills of children with speech sound disorders (SSD), who may be at risk for literacy impairments. No researcher has examined the morphological awareness skills of children with SSD and compared their skills to children with typical speech using tasks representing a comprehensive definition of morphological awareness, which was the main purpose of this study. Method Thirty second- and third-grade students with SSD and 30 with typical speech skills, matched on age and receptive vocabulary, completed four morphological awareness tasks and measures of receptive vocabulary, real-word reading, pseudoword reading, and word-level spelling. Results Results indicated there was no difference between the morphological awareness skills of students with and without SSD. Although morphological awareness was moderately to strongly related to the students' literacy skills, performance on the morphological awareness tasks contributed little to no additional variance to the children's real-word reading and spelling skills beyond what was accounted for by pseudoword reading. Conclusions Findings suggest that early elementary-age students with SSD may not present with concomitant morphological awareness difficulties and that the morphological awareness skills of these students may not play a unique role in their word-level literacy skills. Limitations and suggestions for future research on the morphological awareness skills of children with SSD are discussed.


Author(s):  
Sandra Kotzor ◽  
Allison Wetterlin ◽  
Aditi Lahiri

Bengali has a robust medial geminate/singleton contrast across oral stops and nasals in five places of articulation. This chapter presents a synchronic account of the phonological system involving the consonantal length contrast, which supports an asymmetric moraic representation of geminates. Based on these representational assumptions, two EEG and two behavioural experiments were conducted to investigate the processing of this geminate/singleton contrast by Bengali native speakers. The results reveal a processing asymmetry for the duration contrast: the processing of the duration contrast is indeed asymmetric: a geminate mispronunciation is accepted for a singleton real word, while the reverse is not the case. This provides evidence that the lexical representation of the duration contrast must be asymmetric and thus privative rather than equipollent.


2013 ◽  
Vol 462-463 ◽  
pp. 794-797
Author(s):  
Ru Bo Zhang ◽  
Hai Bo Tong ◽  
Chang Ting Shi

This paper present a hybrid, hierarchical control architecture for mission re-planning and plan repair of autonomous underwater vehicle (AUV) navigating in dynamic and uncertain marine environment. The proposal carries out a component-oriented part-based control architecture structured in three parts: situation reasoning, re-planning trigger and hierarchical re-planning layer. Situation reasoning using the unstructured real-word information obtained by sorts of sensor detectes and recognizes uncertain event. According the event types and influence degree, the re-planning trigger decides the re-planning level. Hierarchical re-planning layer contains mission re-planning, task re-planning and behavior re-planning. Different re-planning level depends on the result of re-planning trigger. Preliminary versions of the architecture have been integrated and tested in a marine simulation environment.


2021 ◽  
Vol 32 ◽  
pp. S171
Author(s):  
A. Caetano ◽  
J. Monteiro ◽  
A. Elvas ◽  
C. Costa ◽  
F. Salgueiro ◽  
...  

2021 ◽  
Vol 429 ◽  
pp. 119260
Author(s):  
Fabrizio Scotto Di Clemente ◽  
Alessandro Tessitore ◽  
Marcello Silvestro ◽  
Giorgia Battista ◽  
Gioacchino Tedeschi ◽  
...  

RMD Open ◽  
2018 ◽  
Vol 4 (2) ◽  
pp. e000809 ◽  
Author(s):  
Kim Lauper ◽  
Denis Mongin ◽  
Florenzo Iannone ◽  
Eirik Klami Kristianslund ◽  
Tore K Kvien ◽  
...  

ObjectiveTo compare the real-word effectiveness of subcutaneous tocilizumab (TCZ-SC) and intravenous tocilizumab (TCZ-IV) in rheumatoid arthritis (RA).MethodsPatients with RA with TCZ from eight European registries were included. Drug retention was compared using unadjusted Kaplan-Meier and Cox models adjusted for baseline patient, disease and treatment characteristics, using a strata term for year of treatment initiation and country of registry. The proportions of patients achieving Clinical Disease Activity Index (CDAI) remission and low disease activity (LDA) at 1 year were compared using samples matched on the same covariates and corrected for attrition using LUNDEX.Results3448 patients were retrieved, 2414 with TCZ-IV and 1034 with TCZ-SC. Crude median retention was 3.52 years (95% CI 3.22 to 3.85) for TCZ-IV and 2.12 years for TCZ-SC (95% CI 1.88 to 2.38). In a country-stratified and year of treatment initiation–stratified, covariate-adjusted analysis, hazards of discontinuation were similar between TCZ-SC and TCZ-IV treated patients (HR 0.93, 95% CI 0.80 to 1.09). The average adjusted CDAI change at 1 year was similar in both groups (−6.08). After matching, with 560 patients in each group, CDAI remission corrected for attrition at 1 year was also similar between TCZ-SC and TCZ-IV (10.4% in TCZ-IV vs 12.8% in TCZ-SC (difference: 2.4%, bootstrap 95% CI −2.1% to 7.6%)), but CDAI LDA was lower in TCZ-IV patients: 41.0% in TCZ-IV versus 49.1% in TCZ-SC (difference: 8.0 %; bootstrap 95% CI 2.4% to 12.4%).ConclusionWith similar retention and effectiveness, TCZ-SC is an adequate alternative to TCZ-IV for RA. When possible, considering the costs of the TCZ-IV route, TCZ-SC should be the preferred mode of administration.


Author(s):  
Md. Mashod Rana ◽  
Mohammad Tipu Sultan ◽  
M. F. Mridha ◽  
Md. Eyaseen Arafat Khan ◽  
Md. Masud Ahmed ◽  
...  
Keyword(s):  

Sign in / Sign up

Export Citation Format

Share Document