Fatty acid desaturase activity in mature red blood cells and implications for blood storage quality

Transfusion ◽  
2021 ◽  
Author(s):  
Tiffany Thomas ◽  
Francesca Cendali ◽  
Xiaoyun Fu ◽  
Fabia Gamboni ◽  
Evan J. Morrison ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Red Blood Cells ◽  
Blood Cells ◽  
Desaturase Activity ◽  
Fatty Acid Desaturase ◽  
Blood Storage ◽  
Storage Quality

Cell Surface Alterations during Blood-Storage Characterized by Artificial Aggregation of Washed Red Blood Cells

Vox Sanguinis ◽  
1985 ◽  
Vol 49 (2) ◽  
pp. 86-91
Author(s):  
E. Hessel ◽  
D. Lerche
Keyword(s):  
Cell Surface ◽  
Red Blood Cells ◽  
Blood Cells ◽  
Blood Storage

[12] Fatty acid synthase from red blood cells

1981 ◽  
pp. 97-103 ◽  
Author(s):  
Robert A. Jenik ◽  
John W. Porter
Keyword(s):  
Fatty Acid ◽  
Red Blood Cells ◽  
Blood Cells ◽  
Fatty Acid Synthase

The relationship between the phospholipid fatty acid composition of red blood cells, plasma lipids, and apolipoproteins

Metabolism ◽  
1993 ◽  
Vol 42 (5) ◽  
pp. 562-568 ◽  
Author(s):  
N. Theret ◽  
J.M. Bard ◽  
M.C. Nuttens ◽  
J.M. Lecerf ◽  
C. Delbart ◽  
...  
Keyword(s):  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Red Blood Cells ◽  
Acid Composition ◽  
Blood Cells ◽  
Plasma Lipids ◽  
Phospholipid Fatty Acid ◽  
Phospholipid Fatty Acid Composition ◽  
The Relationship

scholarly journals Indices of fatty acid desaturase activity in healthy human subjects: effects of different types of dietary fat

2013 ◽  
Vol 110 (5) ◽  
pp. 871-879 ◽  
Author(s):  
Bengt Vessby ◽  
Inga-Britt Gustafsson ◽  
Siv Tengblad ◽  
Lars Berglund
Keyword(s):  
Skeletal Muscle ◽  
Fatty Acid ◽  
Dietary Fat ◽  
Desaturase Activity ◽  
Dietary Intervention ◽  
Activity Index ◽  
Human Subjects ◽  
Fatty Acid Desaturase ◽  
Δ9 Desaturase ◽  
Different Types

Δ9-Desaturase (stearoyl-CoA desaturase 1, SCD-1) regulates the desaturation of SFA, mainly stearic and palmitic, to MUFA. Δ6-Desaturase (D6D) and Δ5-desaturase (D5D) are involved in the metabolism of linoleic and α-linolenic acid to polyunsaturated metabolites. The objective of the present study was to study the effects of different types of dietary fat on indices of fatty acid desaturase (FADS) activity (evaluated as product:precursor ratios) in plasma and skeletal muscle in human subjects. A high SCD-1 index has been related to obesity and metabolic disorders, while the D5D index is associated with insulin sensitivity. Fatty acid composition of serum and skeletal muscle lipids was analysed by GLC during a randomised, controlled, 3-month dietary intervention in healthy subjects. A comparison of the effects of a diet containing butter fat (SFA, n 17) with a diet containing monounsaturated fat (MUFA, n 17), keeping all other dietary components constant, showed a reduced SCD-1 activity index by 20 % on the MUFA diet compared with the SFA diet assessed in serum cholesteryl esters. The D6D and D5D indices remained unaffected. Supplementation with long-chain n-3 fatty acids reduced the SCD-1 index by a similar magnitude while the D6D index decreased and the D5D index increased. It is concluded that changes in the type of fat in the diet affect the indices of FADS activity in serum and skeletal muscle in human subjects. The desaturase activity indices estimated from the serum lipid ester composition are significantly related to corresponding indices studied in skeletal muscle phospholipids.

Drug-induced alterations in hepatic fatty acid desaturase activity

1975 ◽  
Vol 24 (13-14) ◽  
pp. 1343-1347 ◽  
Author(s):  
Mark R. Montgomery ◽  
Jordan L. Holtzman
Keyword(s):  
Fatty Acid ◽  
Desaturase Activity ◽  
Fatty Acid Desaturase ◽  
Drug Induced ◽  
Hepatic Fatty Acid

Effects of storage time and added antioxidant on fatty acid composition of red blood cells at −20°C

Lipids ◽  
2006 ◽  
Vol 41 (4) ◽  
pp. 401-404 ◽  
Author(s):  
Anna R. Magnusardottir ◽  
Gudrun V. Skuladottir
Keyword(s):  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Red Blood Cells ◽  
Acid Composition ◽  
Blood Cells ◽  
Storage Time

Fatty acid synthetase from pigeon red blood cells

1981 ◽  
Vol 13 (4) ◽  
pp. 423-429
Author(s):  
Robert A. Jenik ◽  
John W. Porter
Keyword(s):  
Fatty Acid ◽  
Red Blood Cells ◽  
Blood Cells ◽  
Fatty Acid Synthetase

scholarly journals The Fatty Acid Composition of Red Blood Cells in Mildly Demented Dogs and of Commercially Available Dog Foods in Japan

2008 ◽  
Vol 17 (2) ◽  
pp. 163-171
Author(s):  
Tomohito Hamazaki ◽  
Hajime Shimokawa ◽  
Yoshihiro Terashima ◽  
Miho Itomura ◽  
Kei Hamazaki ◽  
...  
Keyword(s):  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Red Blood Cells ◽  
Acid Composition ◽  
Blood Cells

Red Blood Cells have Active GPx4: Implications for Blood Storage

2020 ◽  
Vol 159 ◽  
pp. S99
Author(s):  
Jeffrey Stolwijk ◽  
Jonathan Stefely ◽  
Brett Wagner ◽  
Thomas Raife ◽  
Garry Buettner
Keyword(s):  
Red Blood Cells ◽  
Blood Cells ◽  
Blood Storage
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