scholarly journals Is sexual risk behaviour associated with an increased risk of transfusion‐transmissible infections in blood donors from Western and Pacific countries? A systematic review and meta‐analysis

Vox Sanguinis ◽  
2019 ◽  
Vol 115 (2) ◽  
pp. 107-123
Author(s):  
Hans Van Remoortel ◽  
Wout Matthysen ◽  
Bert Avau ◽  
Veerle Compernolle ◽  
Philippe Vandekerckhove ◽  
...  
Keyword(s):  
Systematic Review ◽  
Sexual Risk ◽  
Blood Donors ◽  
Meta Analysis ◽  
Risk Behaviour ◽  
Sexual Risk Behaviour ◽  
Increased Risk

scholarly journals Self-collection of samples as an additional approach to deliver testing services for sexually transmitted infections: a systematic review and meta-analysis

2019 ◽  
Vol 4 (2) ◽  
pp. e001349 ◽  
Author(s):  
Yasmin Ogale ◽  
Ping Teresa Yeh ◽  
Caitlin E Kennedy ◽  
Igor Toskin ◽  
Manjulaa Narasimhan
Keyword(s):  
Systematic Review ◽  
Adverse Events ◽  
Sexual Risk ◽  
Meta Analysis ◽  
Risk Behaviour ◽  
Case Finding ◽  
Sexual Risk Behaviour ◽  
Sexually Transmitted ◽  
Sti Testing ◽  
Additional Approach

BackgroundSelf-collection of samples for diagnostic testing offers the advantages of patient autonomy, confidentiality and convenience. Despite data showing their feasibility and accuracy, there is a need to better understand how to implement such interventions for sexually transmitted infections (STIs). To support WHO guidelines on self-care interventions, we conducted a systematic review to investigate whether self-collection of samples should be made available as an additional approach to deliver STI testing services.MethodsPeer-reviewed studies were included if they compared individuals who self-collected samples for chlamydia, gonorrhoea, syphilis and/or trichomonas testing to individuals who had samples collected by clinicians on the following outcomes: uptake/frequency of STI testing, social harms/adverse events, positive yield (case finding), linkage to clinical assessment/treatment and reported sexual risk behaviour. We searched PubMed, CINAHL, LILACS and EMBASE for articles published through July 2018. Risk of bias was assessed using the Cochrane tool for randomised controlled trials (RCTs) and the Evidence Project tool for non-RCTs. Meta-analysis was conducted using random effects models to generate pooled estimates of relative risk (RR).ResultsEleven studies, including five RCTs and six observational studies with a total of 202 745 participants, met inclusion criteria. Studies were conducted in Australia, Denmark and the USA. Meta-analysis found that programmes offering self-collection of samples increased overall uptake of STI testing services (RR: 2.941, 95% CI 1.188 to 7.281) and case finding (RR: 2.166, 95% CI 1.043 to 4.498). No studies reported measuring STI testing frequency, social harms/adverse events, linkage to care or sexual risk behaviour.DiscussionWhile greater diversity in study designs, outcomes and settings would strengthen the evidence base, findings from this review suggest that self-collection of STI samples could be an effective additional strategy to increase STI testing uptake.Prospero registration numberPROSPERO CRD42018114866.

Hepatitis B vaccination and changes in sexual risk behaviour among men who have sex with men in Amsterdam

2008 ◽  
Vol 137 (4) ◽  
pp. 504-512 ◽  
Author(s):  
M. XIRIDOU ◽  
J. WALLINGA ◽  
N. DUKERS-MUIJERS ◽  
R. COUTINHO
Keyword(s):  
High Risk ◽  
Hepatitis B ◽  
Sexual Risk ◽  
Vaccination Campaign ◽  
Risk Behaviour ◽  
Hepatitis B Vaccination ◽  
Sexual Risk Behaviour ◽  
Increased Risk ◽  
Sex With Men ◽  
The Impact

SUMMARYThe impact of hepatitis B vaccination in men having sex with men in Amsterdam has been marginal until now, possibly because of increases in sexual risk behaviour counterbalancing the effect of vaccination. A mathematical model is used to describe the hepatitis B epidemic. The model shows that, with the current vaccination coverage, the decrease in incidence is small in the beginning. However, the number of infections prevented per vaccine administered rises over time. Nevertheless, increased risk behaviour reduces the benefit of vaccination. Targeting high-risk men is more successful in reducing and containing the epidemic than targeting low-risk men. In conclusion, the vaccination campaign is effective and should be intensified. High-risk men should be targeted for vaccination and for risk reduction.

scholarly journals HIV Vulnerability and Sexual Risk Behaviour of the Drayang Girls in Bhutan

2019 ◽  
Vol 17 (1) ◽  
pp. 24-33
Author(s):  
Lekey Khandu ◽  
P. Zwanikken ◽  
S. Wangdi
Keyword(s):  
Hepatitis B ◽  
Condom Use ◽  
Sexual Risk ◽  
Living Arrangements ◽  
Risk Behaviour ◽  
Transactional Sex ◽  
Sexual Risk Behaviour ◽  
Transmitted Infection ◽  
Targeted Interventions ◽  
Increased Risk

Introduction: The rapid socio-economic development in Bhutan has brought changes in individual lifestyles resulting in increased risk behavior of the urban population, particularly the Drayang girls. This study investigated the underlying factors influencing the sexual risk behaviour of Drayang girls and their vulnerability to HIV and Sexually Transmitted Infection (STI). The Drayangs are dance bars in Bhutan where the women perform Bhutanese songs/dances on the stage to entertain the bar patrons and making them pay for their performance. Methods: This is a cross-sectional descriptive study conducted from May-July 2015 in three urban districts (Thimphu, Paro, and Phuentsholing) of Bhutan. The convenient non-random sampling method was used to recruit the respondents. We have collected the data using structured questionnaires including the taking of blood samples for HIV, Hepatitis B, and Syphilis testing. Results: Of the 245 Drayang girls recruited for this study, 28.2% have engaged in transactional sex and 71.8% in non-transactional sex within last month. Condom use during transactional sex was 36.2% and non-transactional sex was 21.6%. The prevalence of HIV was 0.82%, hepatitis B 6.9%, and syphilis 2.8%. The factors such as marital status (divorced and unmarried), living arrangements, current living cities, and alcohol consumption were significantly (p<0.05) associated with transactional sex among Drayang girls. Conclusion: Although the prevalence of HIV and STIs is low among the Drayang girls, the presence of high riskbehavior with low condom use still makes them vulnerable to HIV and STIs. The study recommends putting more effort in prevention of HIV and STI by increasing awareness of HIV and STI, targeted interventions like Behaviour Change Communications (BCC), condom promotion, condom negotiation skills and access for testing and treatment of HIV and STI.

scholarly journals EXPRESS: Stroke risk following traumatic brain injury: systematic review and meta-analysis

2021 ◽  
pp. 174749302110042
Author(s):  
Grace Mary Turner ◽  
Christel McMullan ◽  
Olalekan Lee Aiyegbusi ◽  
Danai Bem ◽  
Tom Marshall ◽  
...  
Keyword(s):  
Systematic Review ◽  
Stroke Risk ◽  
Meta Analysis ◽  
Vitamin K Antagonists ◽  
Cochrane Library ◽  
Control Group ◽  
Large Sample Size ◽  
Hazard Ratios ◽  
Increased Risk ◽  
The Cochrane Library

Aims To investigate the association between TBI and stroke risk. Summary of review We undertook a systematic review of MEDLINE, EMBASE, CINAHL, and The Cochrane Library from inception to 4th December 2020. We used random-effects meta-analysis to pool hazard ratios (HR) for studies which reported stroke risk post-TBI compared to controls. Searches identified 10,501 records; 58 full texts were assessed for eligibility and 18 met the inclusion criteria. The review included a large sample size of 2,606,379 participants from four countries. Six studies included a non-TBI control group, all found TBI patients had significantly increased risk of stroke compared to controls (pooled HR 1.86; 95% CI 1.46-2.37). Findings suggest stroke risk may be highest in the first four months post-TBI, but remains significant up to five years post-TBI. TBI appears to be associated with increased stroke risk regardless of severity or subtype of TBI. There was some evidence to suggest an association between reduced stroke risk post-TBI and Vitamin K antagonists and statins, but increased stroke risk with certain classes of antidepressants. Conclusion TBI is an independent risk factor for stroke, regardless of TBI severity or type. Post-TBI review and management of risk factors for stroke may be warranted.

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