Assessing sensitivity and specificity of the Manchester Triage System in the evaluation of acute coronary syndrome in adult patients in emergency care: a systematic review protocol

Author(s):  
Fernanda Ayache Nishi ◽  
Flávia Oliveira de Motta Maia ◽  
Dina Almeida de Lopes Monteiro da Cruz
BMJ Open ◽  
2016 ◽  
Vol 6 (5) ◽  
pp. e010609 ◽  
Author(s):  
Aaron M Orkin ◽  
Jeffrey D Curran ◽  
Melanie K Fortune ◽  
Allison McArthur ◽  
Emma J Mew ◽  
...  

2020 ◽  
Author(s):  
Sohaib R Rufai ◽  
Noor ul Owase Jeelani ◽  
Rebecca J McLean

Abstract Introduction Craniosynostosis is characterised by the premature fusion of cranial sutures. This can be associated with raised intracranial pressure (ICP), which can lead to developmental delay, visual impairment and death. Treatment involves surgical expansion of the skull vault. There is no consensus over who to treat and when. Intracranial pressure is difficult to estimate in a child and existing methods possess sub-optimal diagnostic accuracy to be employed as screening tools. Here, we propose a systematic review protocol to examine the role of optical coherence tomography (OCT) in early detection of raised ICP in craniosynostosis. Methods Electronic searches in the Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE and Embase will identify studies featuring OCT in detecting raised ICP in children with craniosynostosis. Two independent researchers will identify studies for inclusion using a screening questionnaire. Quality will be assessed using the National Institutes of Health (NIH) Quality Assessment Tool for Observational Cohort and Cross-Sectional Studies. The primary outcome measure is the sensitivity and specificity of OCT in detecting raised ICP in children with craniosynostosis. Secondary outcomes measures include the sensitivity and specificity of other surrogate measures for raised ICP, OCT parameters used and normal ranges for ICP reported. A formal narrative synthesis with descriptive statistics will be presented. Discussion The proposed study will be the first to examine the role of optical coherence tomography in the early recognition of raised intracranial pressure in craniosynostosis, thereby addressing an important clinical problem in paediatric ophthalmology and craniofacial surgery. This systematic review protocol provides transparency to the proposed methods and reduces the possibility of duplication. The proposed methods reflect those prescribed by the Cochrane Collaboration. Systematic review registration International Prospective Register for Systematic Reviews (PROSPERO) number CRD42019147693


2020 ◽  
Vol 132 (11-12) ◽  
pp. 277-282
Author(s):  
Daniel Kiblboeck ◽  
Klara Steinrueck ◽  
Christian Nitsche ◽  
Wolfgang Lang ◽  
Joerg Kellermair ◽  
...  

2019 ◽  
Vol 36 (4) ◽  
pp. 231-238 ◽  
Author(s):  
Maria Clara Magalhães-Barbosa ◽  
Jaqueline Rodrigues Robaina ◽  
Arnaldo Prata-Barbosa ◽  
Claudia de Souza Lopes

ObjectiveTo present a systematic review on the reliability of triage systems for paediatric emergency care.MethodsA search of MEDLINE, Cochrane Library, Latin American and Caribbean Health Sciences Literature, Scientific Electronic Library Online, Nursing Database Index and Spanish Health Sciences Bibliographic Index for articles in English, French, Portuguese or Spanish was conducted to identify reliability studies of five-level triage systems for patients aged 0–18 years published up to April 2018. Two reviewers performed study selection, data extraction and quality assessment as recommended by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement.ResultsTwenty studies on nine triage systems were selected: the National Triage System (n=1); the Australasian Triage Scale (n=3); the paediatric Canadian Triage and Acuity Scale (PedCTAS) (n=5); the Manchester Triage System (MTS) (n=1); the Emergency Severity Index (ESI) (n=5); an adaptation of the South African Triage Scale for the Princess Marina Hospital in Botswana (n=1); the Soterion Rapid Triage System (n=1); the Rapid Emergency Triage and Treatment System-paediatric version (n=2); the Paediatric Risk Classification Protocol (n=1). Ten studies were performed with actual patients, while the others used hypothetical scenarios. The studies were rated low (n=14) or moderate (n=6) quality. Kappa was the most used statistic, although many studies did not specify the weighting. PedCTAS, MTS and ESI V.4 exhibited substantial to almost perfect agreement in moderate quality studies.ConclusionsThere is some evidence on the reliability of the PedCTAS, MTS and ESI V.4, but most studies are limited to the countries where they were developed. Efforts are needed to improve the quality of the studies, and cross-cultural adaptation of those tools is recommended in countries with different professional qualification and sociocultural contexts.


Author(s):  
Vivian Ellen Tácito Gouvêa ◽  
Marco Antonio Moura Reis ◽  
Gustavo Maciel Gouvêa ◽  
Helbert do Nascimento Lima ◽  
Allan Abuabara

BMJ Open ◽  
2020 ◽  
Vol 10 (7) ◽  
pp. e037833
Author(s):  
Sohaib R Rufai ◽  
Noor ul Owase Jeelani ◽  
Rebecca J McLean

IntroductionIntracranial hypertension (ICH) in children can have deleterious effects on the brain and vision. It is notoriously difficult to estimate intracranial pressure (ICP) in children and existing methods deliver suboptimal diagnostic accuracy to be used as screening tools. Optical coherence tomography (OCT) may represent a valuable, non-invasive surrogate measure of ICP, as has been demonstrated in a number of associated conditions affecting adults. More recently, OCT has been employed within the paediatric age group. However, the role of OCT in detecting ICH in children has not been rigorously assessed in a systematic review for all relevant conditions. Here, we propose a systematic review protocol to examine the role of OCT in the detection of ICH in children.Methods and analysisElectronic searches in the Cochrane Central Register of Controlled Trials, Medline, Embase, Web of Science and PubMed will identify studies featuring OCT in detecting ICH in children. Two independent screeners will identify studies for inclusion using a screening questionnaire. The systematic search and screening will take place between 2 April 2020 and 1 June 2020, while we aim to complete data analysis by 1 September 2020. Quality assessment will be performed using the National Institutes of Health Quality Assessment Tool for Observational Cohort and Cross-Sectional Studies. The primary outcome measure is the sensitivity and specificity of OCT in detecting ICH in children. Secondary outcomes measures include conditions associated with ICH per study, direct ICP monitoring, sensitivity and specificity of other measures for ICP and OCT parameters used.Ethics and disseminationEthical approval is not required for the proposed systematic review as no primary data will be collected. The findings will be disseminated through presentations at scientific meetings and peer-reviewed journal publication.PROSPERO registration numberCRD42019154254.


2020 ◽  
Author(s):  
Sean Carruthers ◽  
Gemma Brunetti ◽  
Susan Rossell

Schizophrenia spectrum disorders are chronic and debilitating mental illnesses characterised by both cognitive impairments and sleep deficits. In this systematic review protocol, we outline an approach to examine the available literature investigating the relationship between sleep and cognition in individuals with schizophrenia spectrum disorder.


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