Detection techniques for singlet oxygen production during photodynamic therapy (Conference Presentation)

2016 ◽  
Author(s):  
Buhong Li
Keyword(s):  
Photodynamic Therapy ◽  
Singlet Oxygen ◽  
Oxygen Production ◽  
Detection Techniques

The Measurement of Singlet Oxygen Production in an Experimental Tongue Cancer Model as an Indicator for Photodynamic Therapy

2013 ◽  
Vol 136 (0) ◽  
pp. 62-69
Author(s):  
Ying-Ying Wu ◽  
Toru Hirano ◽  
Junko Yamamoto ◽  
Guang-Wu Huang ◽  
Seiji Yamamoto ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Singlet Oxygen ◽  
Tongue Cancer ◽  
Oxygen Production ◽  
Cancer Model

scholarly journals Tritolylporphyrin dimer as a new potent hydrophobic sensitizer for photodynamic therapy of melanoma.

2001 ◽  
Vol 48 (1) ◽  
pp. 277-282 ◽  
Author(s):  
A Drzewiecka ◽  
K Urbańska ◽  
Z Matuszak ◽  
M Pineiro ◽  
L G Arnaut ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Quantum Yield ◽  
Singlet Oxygen ◽  
Biological Effect ◽  
Photophysical Properties ◽  
Red Light ◽  
Human Melanoma ◽  
Oxygen Production ◽  
Absorption And Emission ◽  
Emission Properties

We report the synthesis, photochemical and photophysical properties and preliminary studies on biological effect of a new tritolylporphyrin dimer (T-D). Absorption and emission properties of T-D suggest its possible use in photodynamic therapy. T-D is capable of singlet oxygen production with 0.8 quantum yield. It also has a high photostability. The photodynamic properties of the dimer were examined following the growth of SKMEL 188 (human melanoma) cells irradiated with red light (cut off < 630 nm). The surviving fraction of the cells decreased about 3-fold (vs. non-irradiated cells) for an 81 J/cm dose. Our results suggest that tritolylporphyrine dimer T-D may be an interesting hydrophobic sensitizer for photodynamic therapy.

A zwitterionic red-emitting water-soluble conjugated polymer with high resistance to nonspecific binding for two-photon cell imaging and good singlet oxygen production capability

2021 ◽  
Author(s):  
Yan-Qin Huang ◽  
Shan-Shan Jiang ◽  
Li-Xiang Pan ◽  
Rui Zhang ◽  
Kun-Lin Liu ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Conjugated Polymers ◽  
Singlet Oxygen ◽  
High Resistance ◽  
Conjugated Polymer ◽  
Cell Imaging ◽  
Water Soluble ◽  
Oxygen Production ◽  
Nonspecific Binding ◽  
Two Photon

Water-soluble conjugated polymers (WSCPs) with dual capability of two-photon imaging and singlet oxygen (1O2) production have become one type of the most promising agents in noninvasive imaging guided photodynamic therapy...

An acid-cleavable phthalocyanine tetramer as an activatable photosensitiser for photodynamic therapy

2016 ◽  
Vol 45 (33) ◽  
pp. 13021-13024 ◽  
Author(s):  
Sun Y. S. Chow ◽  
Pui-Chi Lo ◽  
Dennis K. P. Ng
Keyword(s):  
Photodynamic Therapy ◽  
Singlet Oxygen ◽  
Fluorescence Emission ◽  
Oxygen Production ◽  
Enhanced Fluorescence ◽  
Acidic Environments

A novel self-quenched phthalocyanine tetramer has been prepared which can be activated in acidic environments, resulting in enhanced fluorescence emission and singlet oxygen production.

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