Development of a free-solution SERS-based assay for point-of-care oral cancer biomarker detection using DNA-conjugated gold nanoparticles

Author(s):  
Sungyub Han ◽  
Luke A. Oaks ◽  
Andrea K. Locke ◽  
Yi-Shing Lisa Cheng ◽  
Gerard L. Coté
2021 ◽  
Author(s):  
Hua En Chueh ◽  
Zi Yu Liao ◽  
Ting Yi Lin ◽  
Hsiang Yu Lei ◽  
Hsing Ying Lin ◽  
...  

2018 ◽  
Vol 6 (19) ◽  
pp. 3000-3012 ◽  
Author(s):  
Namrata Pachauri ◽  
Kashyap Dave ◽  
Amit Dinda ◽  
Pratima R. Solanki

Herein, we report a cerium oxide nanocubes (ncCeO2)–reduced graphene oxide (RGO)-based nanocomposite for the detection of oral cancer biomarker, cytokeratin fragment-21-1 (Cyfra-21-1), using the electrochemical technique.


The Analyst ◽  
2020 ◽  
Vol 145 (15) ◽  
pp. 5113-5117 ◽  
Author(s):  
K. Sudhakara Prasad ◽  
Yousef Abugalyon ◽  
Chunqiang Li ◽  
Feng Xu ◽  
XiuJun Li

Catalytic properties of gold nanoparticles in colour dye degradation are utilized to amplify colorimetric detection signals of a low-cost paper-based immunosensor for instrument-free detection of pancreatic cancer biomarker PEAK1.


Talanta ◽  
2021 ◽  
pp. 122644
Author(s):  
Guillermo Landa ◽  
Laura G. Miranda-Calderón ◽  
Victor Sebastian ◽  
Silvia Irusta ◽  
Gracia Mendoza ◽  
...  

2021 ◽  
Vol 255 ◽  
pp. 13003
Author(s):  
Tommaso Pileri ◽  
Alberto Sinibaldi ◽  
Agostino Occhicone ◽  
Elena Giordani ◽  
Matteo Allegretti ◽  
...  

An optical biosensor for proteomic breast cancer biomarker detection in complex media is presented. Bloch Surface Waves (BSW) excited onto one dimensional photonic crystal (1DPC) were used to probe the interaction of HER2 with three antibody species and an inert protein (Bovine Serum Albumin - BSA). The optical system combines Label-Free readings to track the bioassay real-time development and Fluorescence emission quantification to evaluate the level of specific interaction between the antigen and the antibodies. The results confirm a distinguishable level of affinity between the antibodies and the analyte according to their specificity even at low antibody surface density (about 1173 pg/mm2).


RSC Advances ◽  
2018 ◽  
Vol 8 (48) ◽  
pp. 27091-27100 ◽  
Author(s):  
Abbas Motalebizadeh ◽  
Hasan Bagheri ◽  
Sasan Asiaei ◽  
Nasim Fekrat ◽  
Abbas Afkhami

A smartphone-based microfluidic platform was developed for point-of-care (POC) detection using surface plasmon resonance (SPR) of gold nanoparticles (GNPs).


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