A novel physics-based data augmentation approach for improved robust deep learning in medical imaging: lung nodule CAD false positive reduction in CT low-dose environments

Author(s):  
Muhammad W. Wahi-Anwar ◽  
Nastaran Emaminejad ◽  
Youngwon Choi ◽  
Hyun G. Kim ◽  
William Hsu ◽  
...  
2020 ◽  
Vol 6 (1) ◽  
Author(s):  
Malte Seemann ◽  
Lennart Bargsten ◽  
Alexander Schlaefer

AbstractDeep learning methods produce promising results when applied to a wide range of medical imaging tasks, including segmentation of artery lumen in computed tomography angiography (CTA) data. However, to perform sufficiently, neural networks have to be trained on large amounts of high quality annotated data. In the realm of medical imaging, annotations are not only quite scarce but also often not entirely reliable. To tackle both challenges, we developed a two-step approach for generating realistic synthetic CTA data for the purpose of data augmentation. In the first step moderately realistic images are generated in a purely numerical fashion. In the second step these images are improved by applying neural domain adaptation. We evaluated the impact of synthetic data on lumen segmentation via convolutional neural networks (CNNs) by comparing resulting performances. Improvements of up to 5% in terms of Dice coefficient and 20% for Hausdorff distance represent a proof of concept that the proposed augmentation procedure can be used to enhance deep learning-based segmentation for artery lumen in CTA images.


2020 ◽  
Vol 162 ◽  
pp. 113017 ◽  
Author(s):  
Salsabil Amin El-Regaily ◽  
Mohammed Abdel Megeed Salem ◽  
Mohamed Hassan Abdel Aziz ◽  
Mohamed Ismail Roushdy

2017 ◽  
Vol 140 ◽  
pp. 211-231 ◽  
Author(s):  
Peng Cao ◽  
Xiaoli Liu ◽  
Jian Zhang ◽  
Wei Li ◽  
Dazhe Zhao ◽  
...  

2018 ◽  
Vol 162 ◽  
pp. 109-118 ◽  
Author(s):  
Giovanni Lucca França da Silva ◽  
Thales Levi Azevedo Valente ◽  
Aristófanes Corrêa Silva ◽  
Anselmo Cardoso de Paiva ◽  
Marcelo Gattass

2020 ◽  
Author(s):  
Pui Anantrasirichai ◽  
Juliet Biggs ◽  
Fabien Albino ◽  
David Bull

<p>Satellite interferometric synthetic aperture radar (InSAR) can be used for measuring surface deformation for a variety of applications. Recent satellite missions, such as Sentinel-1, produce a large amount of data, meaning that visual inspection is impractical. Here we use deep learning, which has proved successful at object detection, to overcome this problem. Initially we present the use of convolutional neural networks (CNNs) for detecting rapid deformation events, which we test on a global dataset of over 30,000 wrapped interferograms at 900 volcanoes. We compare two potential training datasets: data augmentation applied to archive examples and synthetic models. Both are able to detect true positive results, but the data augmentation approach has a false positive rate of 0.205% and the synthetic approach has a false positive rate of 0.036%.  Then, I will present an enhanced technique for measuring slow, sustained deformation over a range of scales from volcanic unrest to urban sources of deformation such as coalfields. By rewrapping cumulative time series, the detection performance is improved when the deformation rate is slow, as more fringes are generated without altering the signal to noise ratio. We adapt the method to use persistent scatterer InSAR data, which is sparse in nature,  by using spatial interpolation methods such as modified matrix completion Finally, future perspectives for machine learning applications on InSAR data will be discussed.</p>


2021 ◽  
Vol 2021 ◽  
pp. 1-10
Author(s):  
Fukui Liang ◽  
Caiqin Li ◽  
Xiaoqin Fu

Lung cancer is one of the most malignant tumors. If it can be detected early and treated actively, it can effectively improve a patient’s survival rate. Therefore, early diagnosis of lung cancer is very important. Early-stage lung cancer usually appears as a solitary lung nodule on medical imaging. It usually appears as a round or nearly round dense shadow in the chest radiograph. It is difficult to distinguish lung nodules and lung soft tissues with the naked eye. Therefore, this article proposes a deep learning-based artificial intelligence chest CT lung nodule detection performance evaluation study, aiming to evaluate the value of chest CT imaging technology in the detection of noncalcified nodules and provide help for the detection and treatment of lung cancer. In this article, the Lung Medical Imaging Database Consortium (LIDC) was selected to obtain 536 usable cases based on inclusion criteria; 80 cases were selected for examination, artificial intelligence software, radiologists, and thoracic imaging specialists. Using 80 pulmonary nodules detection in each case, the pathological type of pulmonary nodules, nonlime tuberculous test results, detection sensitivity, false negative rate, false positive rate, and CT findings were individually analyzed, and the detection efficiency software of artificial intelligence was evaluated. Experiments have proved that the sensitivity of artificial intelligence software to detect noncalcified nodules in the pleural, peripheral, central, and hilar areas is higher than that of radiologists, indicating that the method proposed in this article has achieved good detection results. It has a better nodule detection sensitivity than a radiologist, reducing the complexity of the detection process.


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