Caffeine Enhances Cognitive Function and Skill Performance during Simulated Soccer Activity

2009 ◽  
Vol 19 (4) ◽  
pp. 410-423 ◽  
Author(s):  
Andrew Foskett ◽  
Ajmol Ali ◽  
Nicholas Gant
Keyword(s):  
Cognitive Function ◽  
Movement Time ◽  
Soccer Players ◽  
Cognitive Demands ◽  
Double Blind ◽  
Caffeine Ingestion ◽  
Jump Performance ◽  
Skill Performance ◽  
And Performance ◽  
Sporting Performance

There is little evidence regarding the benefits of caffeine ingestion on cognitive function and skillful actions during sporting performance, especially in sports that are multifaceted in their physiological, skill, and cognitive demands.Purpose:To examine the influence of caffeine on performance during simulated soccer activity.Methods:Twelve male soccer players completed two 90-min soccer-specific intermittent running trials interspersed with tests of soccer skill (LSPT). The trials were separated by 7 days and adhered to a randomized crossover design. On each occasion participants ingested 6 mg/kg body mass (BM) of caffeine (CAF) or a placebo (PLA) in a double-blind fashion 60 min before exercise. Movement time, penalties accrued, and total time were recorded for the LSPT. Physiological and performance markers were measured throughout the protocol. Water (3 ml/kg BM) was ingested every 15 min.Results:Participants accrued significantly less penalty time in the CAF trial (9.7 ± 6.6 s vs. PLA 11.6 ± 7.4 s; p = .02), leading to a significantly lower total time in this trial (CAF 51.6 ± 7.7 s vs. PLA 53.9 ± 8.5 s; p = .02). This decrease in penalty time was probably attributable to an increased passing accuracy in the CAF trial (p = .06). Jump height was 2.7% (± 1.1%) higher in the CAF trial (57.1 ± 5.1 cm vs. PLA 55.6 ± 5.1 cm; p = .01).Conclusions:Caffeine ingestion before simulated soccer activity improved players’ passing accuracy and jump performance without any detrimental effects on other performance parameters.

Acute Creatine Supplementation and Performance during a Field Test Simulating Match Play in Elite Female Soccer Players

2002 ◽  
Vol 12 (1) ◽  
pp. 33-46 ◽  
Author(s):  
Greg Cox ◽  
Iñigo Mujika ◽  
Douglas Tumilty ◽  
Louise Burke
Keyword(s):  
Placebo Group ◽  
Creatine Supplementation ◽  
Soccer Players ◽  
Exercise Protocol ◽  
Double Blind ◽  
Match Play ◽  
Repeated Sprint ◽  
Glucose Polymer ◽  
Improved Performance ◽  
And Performance

This study investigated the effects of acute creatine (Cr) supplementation on the performance of elite female soccer players undertaking an exercise protocol simulating match play. On two occasions, 7 days apart, 12 players performed 5 X 11-min exercise testing blocks interspersed with 1 min of rest. Each block consisted of 11 all-out 20-m running sprints, 2 agility runs, and 1 precision ball-kicking drill, separated by recovery 20-m walks, jogs, and runs. After the initial testing session, subjects were assigned to either a CREATINE (5 g of Cr, 4 times per day for 6 days) or a PLACEBO group (same dosage of a glucose polymer) using a double-blind research design. Body mass (BM) increased (61.7 ± 8.9 to 62.5 ± 8.9 kg, p < .01) in the CREATINE group; however, no change was observed in the PLACEBO group (63.4 ± 2.9 kg to 63.7 ± 2.5 kg). No overall change in 20-m sprint times and agility run times were observed, although the CREATINE group achieved faster post-supplementation times in sprints 11, 13, 14, 16, 21, 23, 25, 32, and 39 (p < .05), and agility runs3,5,and8 (p < .05). The accuracy of shooting was unaffected in both groups. In conclusion, acute Cr supplementation improved performance of some repeated sprint and agility tasks simulating soccer match play, despite an increase in BM.

Caffeine Ingestion and Performance of a 1,500-Metre Swim

1995 ◽  
Vol 20 (2) ◽  
pp. 168-177 ◽  
Author(s):  
Brian Robert MacIntosh ◽  
Bridget Margarette Wright
Keyword(s):  
Blood Glucose ◽  
Perceived Exertion ◽  
Plasma Potassium ◽  
Electrolyte Balance ◽  
Lower Plasma ◽  
Double Blind ◽  
Caffeine Ingestion ◽  
Warm Up ◽  
Ergogenic Effects ◽  
And Performance

The purpose of this study was to evaluate the potential ergogenic benefit of caffeine in the performance of a 1,500-meter swim. Caffeine (6 mg∙kg−1) or placebo was administered 2-1/2 hrs prior to the swim trial in a double-blind crossover design. Caffeine resulted in a significantly lower perceived exertion for 100-m warm-up swims. Subjects swam significantly (p < 0.05) faster with caffeine (20:58.8 ± 0:36.4, mean ± SEM) than without (21:21.8 ± 0:38). Plasma potassium was significantly lower prior to the swim with caffeine, and blood glucose was higher after that swim. Caffeine provides an ergogenic benefit for a 1,500-meter swim, an event that is completed in less than 25 min. Lower plasma potassium concentration prior to exercise and higher blood glucose following the trial suggest that electrolyte balance and glucose availability may be important aspects of the ergogenic effects of caffeine. Key words: methylxanthines, endurance, exercise, potassium, fatigue, swimming

scholarly journals Genetic Determinants of Neurobehavioral Responses to Caffeine Administration during Sleep Deprivation: A Randomized, Cross Over Study (NCT03859882)

Genes ◽  
2021 ◽  
Vol 12 (4) ◽  
pp. 555
Author(s):  
Mégane Erblang ◽  
Fabien Sauvet ◽  
Catherine Drogou ◽  
Michaël Quiquempoix ◽  
Pascal Van Beers ◽  
...  
Keyword(s):  
Sleep Deprivation ◽  
Nucleotide Polymorphisms ◽  
Genetic Determinants ◽  
Placebo Condition ◽  
Double Blind ◽  
Single Nucleotide ◽  
Psychomotor Vigilance Test ◽  
Tnf Α ◽  
And Performance ◽  
Psychomotor Vigilance

This study investigated whether four single nucleotide polymorphisms (SNPs) moderated caffeine effects on vigilance and performance in a double-blind and crossover total sleep deprivation (TSD) protocol in 37 subjects. In caffeine (2 × 2.5 mg/kg/24 h) or placebo-controlled condition, subjects performed a psychomotor vigilance test (PVT) and reported sleepiness every six hours (Karolinska sleepiness scale (KSS)) during TSD. EEG was also analyzed during the 09:15 PVT. Carriers of the TNF-α SNP A allele appear to be more sensitive than homozygote G/G genotype to an attenuating effect of caffeine on PVT lapses during sleep deprivation only because they seem more degraded, but they do not perform better as a result. The A allele carriers of COMT were also more degraded and sensitive to caffeine than G/G genotype after 20 h of sleep deprivation, but not after 26 and 32 h. Regarding PVT reaction time, ADORA2A influences the TSD effect but not caffeine, and PER3 modulates only the caffeine effect. Higher EEG theta activity related to sleep deprivation was observed in mutated TNF-α, PER3, and COMT carriers, in the placebo condition particularly. In conclusion, there are genetic influences on neurobehavioral impairments related to TSD that appear to be attenuated by caffeine administration. (NCT03859882).

scholarly journals Association of Cognitive Function Screening Results with Adherence and Performance in a Pedometer-Based Intervention

2021 ◽  
pp. 1-9
Author(s):  
Anoop Sheshadri ◽  
Piyawan Kittiskulnam ◽  
Cynthia Delgado ◽  
Rebecca L. Sudore ◽  
Jennifer C. Lai ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Cognitive Function ◽  
Physical Performance ◽  
Mixed Model ◽  
Linear Mixed Model ◽  
Controlled Trial ◽  
Cognitive Status ◽  
Dialysis Patients ◽  
Exercise Interventions ◽  
And Performance

<b><i>Introduction:</i></b> A randomized, controlled trial of a pedometer-based walking intervention with weekly activity goals led to increased walking among dialysis patients. We examined whether impairment per cognitive function screening is associated with adherence and performance in the intervention. <b><i>Methods:</i></b> Thirty dialysis patients were randomly assigned to a 3-month pedometer-based intervention with weekly goals. Participants were administered the Telephone Interview of Cognitive Status (TICS), a test of global mental status. We examined the association of levels of impairment on the TICS (≥33: unimpaired, 26–32: ambiguous impairment, 21–25: mild cognitive impairment [MCI]) with adherence, achieving weekly goals, and increasing steps, physical performance (Short Physical Performance Battery, SPPB), and self-reported physical function (PF) through multivariable linear mixed-model and logistic regression analyses adjusted for age, sex, BMI, dialysis modality, baseline steps, baseline SPPB, and stroke status. <b><i>Results:</i></b> One-third of participants were unimpaired, and 13% had MCI. Participants with worse results on cognitive function screening missed more calls and completed fewer weekly goals than participants with better results. During the intervention, a worse result on cognitive function screening was associated with smaller increases in steps compared to those without impairment: (ambiguous: −620 [95% CI −174, −1,415], MCI: −1,653 [95% CI −120, −3,187]); less improvement in SPPB (ambiguous: −0.22 points [95% CI −0.08, −0.44], MCI: −0.45 [95% CI −0.13, −0.77]); and less improvement in PF (ambiguous: −4.0 points [95% CI −12.2, 4.1], MCI: −14.0 [95% CI −24.9, −3.1]). During the postintervention period, a worse result on cognitive function screening was associated with smaller increases in SPPB (ambiguous: −0.54 [95% CI −1.27, 0.19], MCI: −0.97 [95% CI −0.37, −1.58]) and PF (ambiguous: −3.3 [95% CI −6.5, −0.04], MCI: −10.5 [95% CI −18.7, −2.3]). <b><i>Discussion/Conclusion:</i></b> Participants with worse results on cognitive function screening had worse adherence and derived less benefit from this pedometer-based intervention. Future exercise interventions should be developed incorporating methods to address cognitive impairment, for example, by including caregivers when planning such interventions.

Effects of Folic Acid Combined with DHA Supplementation on Cognitive Function and Amyloid-β-Related Biomarkers in Older Adults with Mild Cognitive Impairment by a Randomized, Double Blind, Placebo-Controlled Trial

2021 ◽  
pp. 1-13
Author(s):  
Dong Bai ◽  
Junting Fan ◽  
Mengyue Li ◽  
Cuixia Dong ◽  
Yiming Gao ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Folic Acid ◽  
Mild Cognitive Impairment ◽  
Cognitive Function ◽  
Digit Span ◽  
Controlled Trial ◽  
Amyloid Β ◽  
Amyloid Β Peptide ◽  
Double Blind ◽  
Full Scale Intelligence Quotient

Background: The neuroprotective benefits of combined folic acid and docosahexaenoic acid (DHA) on cognitive function in mild cognitive impairment (MCI) patients are suggested but unconfirmed. Objective: To explore the effects of 6-month folic acid + DHA on cognitive function in patients with MCI. Methods: Our randomized controlled trial (trial number ChiCTR-IOR-16008351) was conducted in Tianjin, China. We divided 160 MCI patients aged >  60 years into four regimen groups randomly: folic acid (0.8 mg/day) + DHA (800 mg/day), folic acid (0.8 mg/day), DHA (800 mg/day), and placebo, for 6 months. Cognitive function and blood amyloid-β peptide (Aβ) biomarker levels were measured at baseline and 6 months. Cognitive function was also measured at 12 months. Results: A total of 138 patients completed this trial. Folic acid improved the full-scale intelligence quotient (FSIQ), arithmetic, and picture complement scores; DHA improved the FSIQ, information, arithmetic, and digit span scores; folic acid + DHA improved the arithmetic (difference 1.67, 95% CI 1.02 to 2.31) and digital span (1.33, 0.24 to 2.43) scores compared to placebo. At 12 months, all scores declined in the intervention groups. Folic acid and folic acid + DHA increased blood folate (folic acid + DHA: 7.70, 3.81 to 11.59) and S-adenosylmethionine (23.93, 1.86 to 46.00) levels and reduced homocysteine levels (–6.51, –10.57 to –2.45) compared to placebo. DHA lower the Aβ40 levels (–40.57, –79.79 to –1.35) compared to placebo (p <  0.05), and folic acid + DHA reduced the Aβ42 (–95.59, –150.76 to –40.43) and Aβ40 levels (–45.75, –84.67 to –6.84) more than DHA (p <  0.05). Conclusion: Folic acid and DHA improve cognitive function and reduce blood Aβ production in MCI patients. Combination therapy may be more beneficial in reducing blood Aβ-related biomarkers.

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