The Association of Adolescent Fatness and Fitness With Risk Factors for Adult Metabolic Syndrome: A 22-Year Follow-up Study

2014 ◽  
Vol 11 (4) ◽  
pp. 823-830 ◽  
Author(s):  
Yoonsuk Jekal ◽  
YoonMyung Kim ◽  
Ji Eun Yun ◽  
Eun Sung Kim ◽  
Masayo Naruse ◽  
...  

Background:Few studies have been conducted to explore the associations of fatness and fitness during adolescence with risk factors of metabolic syndrome (MetS) during adulthood, particularly in Asians.Methods:Adolescent anthropometric and fitness data were collected during the participants’ high school years (N = 15,896) and their corresponding health examination data from adulthood were taken from the National Health Insurance Corporation (NHIC) in Korea. A total of 1,006 participants (6.3%) were analyzed in the study.Results:The odds ratios (ORs) for being overweight (BMI ≥ 25 kg/m2) during adulthood was 11.87 (95% CI: 4.19–33.59) in men and 8.44 (95% CI: 1.78–40.02) in women, respectively, in the fattest group vs. the leanest group during adolescence. Participants with low fitness levels during adolescence were more likely to be overweight and have abnormal MetS risk factors in adulthood vs. those with high fitness levels. Joint exposure analyses of fatness and fitness showed that male participants who were more fat and unfit during adolescence had 4.11 (95% CI: 1.19–14.14) and 3.04 (95% CI: 1.17–11.12) times higher risk of having abnormal glucose and MetS risks during adulthood, respectively.Conclusions:Fatness and fitness levels during adolescence appear to be significantly associated with the MetS risk factors and prevalence in adulthood in Koreans.

2007 ◽  
Vol 17 (5) ◽  
pp. 424-429 ◽  
Author(s):  
K. Nakamura ◽  
T. Okamura ◽  
H. Kanda ◽  
T. Hayakawa ◽  
A. Okayama ◽  
...  

Public Health ◽  
2008 ◽  
Vol 122 (11) ◽  
pp. 1226-1228 ◽  
Author(s):  
K. Nakamura ◽  
T. Okamura ◽  
H. Kanda ◽  
T. Hayakawa ◽  
Y. Murakami ◽  
...  

2006 ◽  
Vol 24 (11) ◽  
pp. 2305-2309 ◽  
Author(s):  
Koshi Nakamura ◽  
Tomonori Okamura ◽  
Hideyuki Kanda ◽  
Takehito Hayakawa ◽  
Akira Okayama ◽  
...  

Public Health ◽  
2007 ◽  
Vol 121 (3) ◽  
pp. 174-176 ◽  
Author(s):  
Koshi Nakamura ◽  
Tomonori Okamura ◽  
Hideyuki Kanda ◽  
Takehito Hayakawa ◽  
Akira Okayama ◽  
...  

2020 ◽  
Vol 14 (Supplement_1) ◽  
pp. S612-S613
Author(s):  
J M Moon ◽  
E A Kang ◽  
K Han ◽  
S W Hong ◽  
H Soh ◽  
...  

Abstract Background The incidence of inflammatory bowel disease (IBD) is increasing in Asia. Numerous risk factors associated with IBD development have been investigated. This study aimed to demonstrate the risk factors of Crohn’s disease (CD) diagnosed in persons aged >40 years in South Korea and to specify any differences between age groups by using the National Health Insurance Service (NHIS) database. Methods Using the National Health Insurance Service (NHIS) database, a total of 14,060,821 persons aged >40 years who underwent national health screening in 2009 were followed up until December 2017. Patients with newly diagnosed CD were enrolled and compared with non-CD cohort. CD was identified according to the International Classification of Diseases 10th revision and the rare/intractable disease registration programme codes from the NHIS database. The mean follow-up periods were 7.39 years. Age and sex were adjusted for in the multivariate analysis model. Results During the follow-up, 1337 (1.33/100,000) patients developed CD. Men in the middle-aged group (40–64 years) had a higher risk than women (adjusted HR [aHR] 1.46, 95% CI 1.29–1.66); however, this difference tended to disappear as the age of onset increases. In the middle-aged group, patients with a history of smoking (adjusted hazard ratio [aHR] 1.29, 95% confidence interval [CI] 1.06–1.58) and anemia (aHR 1.99, 95% CI 1.67–2.36) had a significantly higher CD risk. In the elderly group (age, ³65 years), ex-smoking and anemia also increased the CD risk (aHR 1.58 [95% CI 1.16–2.18] and 1.91 [95% CI 1.53–2.38], respectively). Especially in the middle-aged group, those with chronic kidney disease (CKD) had a statistically elevated CD risk (aHR 1.38, 95% CI 1.06–1.79). Alcohol consumption and higher body mass index showed negative association trend with CD incidence in both of the age groups. (Middle-aged: aHR 0.76 [95%CI 0.65–0.87] and aHR 0.38 [95%CI 0.27–0.53], respectively) (elderly-group: aHR 0.57 [95%CI 0.42–0.77] and aHR 0.52 [95%CI 0.32-.83], respectively) For regular physical activity and dyslipidemia, negative correlation between CD incidences was proved only in the middle-aged group (aHR 0.85 [95%CI 0.74–0.96] and aHR 0. [95%CI 0.75 [95% CI 0.63–0.89], respectively). Conclusion This study demonstrated four risk factors (ex-smoking, anemia, CKD, and lower BMI) and three possible protective factors (alcohol consumption, physical activity, and dyslipidemia) for CD in Asians age >40 years. Individuals with potential risk factors need more cautious monitoring for CD.


Author(s):  
Yongseok Seo ◽  
Seungyeon Lee ◽  
Joung-Sook Ahn ◽  
Seongho Min ◽  
Min-Hyuk Kim ◽  
...  

(1) Background: The health implications associated with the metabolically healthy obese (MHO) phenotype, in particular related to symptoms of depression, are still not clear. the purpose of this study is to check whether depression and metabolic status are relevant by classifying them into four groups in accordance with the MHO diagnostic standard. Other impressions seen were the differences between sexes and the effects of the MHO on the occurrence of depression. (2) Methods: A sample of 3,586,492 adult individuals from the National Health Insurance Database of Korea was classified into four categories by their metabolic status and body mass index: (1) metabolically healthy non-obese (MHN); (2) metabolically healthy obese (MHO); (3) metabolically unhealthy non-obese (MUN); and (4) metabolically unhealthy obese (MUO). Participants were followed for six to eight years for new incidences of depression. The statistical significance of the general characteristics of the four groups, as well as the mean differences in metabolic syndrome risk factors, was assessed with the use of a one-way analysis of variance (ANOVA). (3) Results: The MHN ratio in women was higher than in men (men 39.3%, women 55.2%). In both men and women, depression incidence was the highest among MUO participants (odds ratio (OR) = 1.01 in men; OR = 1.09 in women). It was concluded as well that, among the risk factors of metabolic syndrome, waist circumference was the most related to depression. Among the four groups, the MUO phenotype was the most related to depression. Furthermore, in women participants, MHO is also related to a higher risk of depressive symptoms. These findings indicate that MHO is not a totally benign condition in relation to depression in women. (4) Conclusion: Therefore, reducing metabolic syndrome and obesity patients in Korea will likely reduce the incidence of depression.


2005 ◽  
Vol 28 (11) ◽  
pp. 859-864 ◽  
Author(s):  
Koshi NAKAMURA ◽  
Tomonori OKAMURA ◽  
Hideyuki KANDA ◽  
Takehito HAYAKAWA ◽  
Takashi KADOWAKI ◽  
...  

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