A new hope? Yoda1 uses the “force” to sensitize cancer cells to TRAIL-mediated apoptosis

2019 ◽  
Vol 11 (518) ◽  
pp. eaaz9752
Author(s):  
Jessica D. Weaver
Keyword(s):  
Shear Stress ◽  
Ion Channel ◽  
Cancer Cells ◽  
Cytotoxic Effects ◽  
Mechanosensitive Ion Channel ◽  
Channel Agonist

A mechanosensitive ion channel agonist mimics shear stress to enhance the cytotoxic effects of TRAIL on cancer cells.

Cytotoxic effects of disulfiram and synergism with cisplatin on ovarian cancer cells in vitro

2018 ◽  
Author(s):  
F Guo ◽  
Z Yang ◽  
J Xu ◽  
J Sehouli ◽  
AE Albers ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Cancer Cells ◽  
Ovarian Cancer Cells ◽  
Cytotoxic Effects

scholarly journals Chondroprotection by urocortin involves blockade of the mechanosensitive ion channel Piezo1

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
K. M. Lawrence ◽  
R. C. Jones ◽  
T. R. Jackson ◽  
R. L. Baylie ◽  
B. Abbott ◽  
...  
Keyword(s):  
Ion Channel ◽  
Mechanosensitive Ion Channel

scholarly journals Enhancement of cytotoxic effects of gemcitabine by Dclk1 inhibition through suppression of Chk1 phosphorylation in human pancreatic cancer cells

2017 ◽  
Vol 38 (5) ◽  
pp. 3238-3244 ◽  
Author(s):  
Daichi Kawamura ◽  
Yoshihiro Takemoto ◽  
Arata Nishimoto ◽  
Koji Ueno ◽  
Tohru Hosoyama ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Cancer Cells ◽  
Human Pancreatic Cancer ◽  
Cytotoxic Effects ◽  
Pancreatic Cancer Cells

scholarly journals The Mechanosensitive Ion Channel TRPV4 is a Regulator of Lung Development and Pulmonary Vasculature Stabilization

2018 ◽  
Vol 11 (5) ◽  
pp. 309-320 ◽  
Author(s):  
Joshua T. Morgan ◽  
Wade G. Stewart ◽  
Robert A. McKee ◽  
Jason P. Gleghorn
Keyword(s):  
Ion Channel ◽  
Lung Development ◽  
Pulmonary Vasculature ◽  
Mechanosensitive Ion Channel

Short- and long-term cytotoxic effects of doxorubicin conjugates with dendrimers and vector protein on MCF-7/MDR1 chemoresistant breast cancer cells

2017 ◽  
Author(s):  
I. A. Zamulaeva ◽  
O. N. Matchuk ◽  
K. A. Churyukina ◽  
V. A. Kudryavtzev ◽  
N. G. Yabbarov ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Cells ◽  
Breast Cancer Cells ◽  
Cytotoxic Effects ◽  
Short And Long Term ◽  
Mcf 7

scholarly journals Estimation of the pore size of the large-conductance mechanosensitive ion channel of Escherichia coli

1997 ◽  
Vol 73 (4) ◽  
pp. 1925-1931 ◽  
Author(s):  
C.C. Cruickshank ◽  
R.F. Minchin ◽  
A.C. Le Dain ◽  
B. Martinac
Keyword(s):  
Escherichia Coli ◽  
Ion Channel ◽  
Pore Size ◽  
Mechanosensitive Ion Channel
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