Effect of high-dose posaconazole on serum levels in adult patients with hematologic malignancy

Posaconazole (POS) appears to have dose-proportional pharmacokinetics, however there is paucity of real-life data. We retrospectively evaluated 67 patients with hematological cancer who had POS dose increase from 300 mg/d to either 400 mg/d (n=52) or 300 mg twice daily (BID; n=15) and POS serum levels measured. Median POS levels were 840 ng/mL, 1625 ng/mL, and 2710 ng/mL on the 300mg/d, 400mg/d and 300mg BID doses respectively. Significant inter-patient variability in serum levels was noted.

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Economic Evaluation of Omalizumab in the Treatment of Severe AllergicAsthma in Adult Patients in Greece: A Cost Effectiveness Analysis ofClinical Trial and Real-Life Data

Pharmacoeconomics open access ◽

10.4172/2472-1042.1000103 ◽

2015 ◽

Vol 01 (01) ◽

Author(s):

Venkateshwarlu Sonathi

Keyword(s):

Economic Evaluation ◽

Cost Effectiveness ◽

Real Life ◽

Cost Effectiveness Analysis ◽

Adult Patients ◽

Life Data ◽

Effectiveness Analysis ◽

Real Life Data

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Real-life data on the effectiveness and safety of dupilumab in adult patients with uncontrolled Chronic Rhinosinusitis with nasal Polyps (CRSwNP)

10.1055/s-0041-1728626 ◽

2021 ◽

Author(s):

R Böscke ◽

K-L Bruchhage

Keyword(s):

Chronic Rhinosinusitis ◽

Nasal Polyps ◽

Real Life ◽

Adult Patients ◽

Life Data ◽

Real Life Data

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Abstract #601 Mortality; Major Adverse Cardiovascular Events (Mace) and Weight are Reduced in 400 Hypogonadal Men on Long-Term Testosterone Therapy (TTH) Compared to 376 Untreated Hypogonadal Controls: Real-Life Data from A 10-Year Registry

Endocrine Practice ◽

10.1016/s1530-891x(20)47240-4 ◽

2018 ◽

Vol 24 ◽

pp. 143

Author(s):

Farid Saad ◽

Ahmad Haider ◽

Karim Haider ◽

Gheorghe Doros ◽

Abdulmaged Traish

Keyword(s):

Cardiovascular Events ◽

Real Life ◽

Major Adverse Cardiovascular Events ◽

Testosterone Therapy ◽

Life Data ◽

Real Life Data

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Abstract #1216 Improvement of Blood Pressure (Bp); Heart Rate and Other Hemodynamic Markers in Hypogonadal Patients with Hypertension Receiving Long-Term Testosterone Therapy (Tth) Compared to Untreated Hypogonadal Controls: Real-Life Data from a 10-Year Registry

Endocrine Practice ◽

10.1016/s1530-891x(20)47508-1 ◽

2018 ◽

Vol 24 ◽

pp. 312-313

Author(s):

Farid Saad ◽

Ahmad Haider ◽

Karim Haider ◽

Gheorghe Doros ◽

Abdulmaged Traish

Keyword(s):

Blood Pressure ◽

Heart Rate ◽

Real Life ◽

Testosterone Therapy ◽

Life Data ◽

Real Life Data

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Neuropsychology in the Real World

Zeitschrift für Neuropsychologie ◽

10.1024/1016-264x/a000139 ◽

2014 ◽

Vol 25 (4) ◽

pp. 233-238 ◽

Cited By ~ 2

Author(s):

Martin Peper ◽

Simone N. Loeffler

Keyword(s):

Neuropsychological Assessment ◽

Real World ◽

Ecological Validity ◽

Real Life ◽

Emotional States ◽

Context Sensitive ◽

Traditional Assessment ◽

Life Data ◽

Real Life Data ◽

Assessment And Treatment

Current ambulatory technologies are highly relevant for neuropsychological assessment and treatment as they provide a gateway to real life data. Ambulatory assessment of cognitive complaints, skills and emotional states in natural contexts provides information that has a greater ecological validity than traditional assessment approaches. This issue presents an overview of current technological and methodological innovations, opportunities, problems and limitations of these methods designed for the context-sensitive measurement of cognitive, emotional and behavioral function. The usefulness of selected ambulatory approaches is demonstrated and their relevance for an ecologically valid neuropsychology is highlighted.

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