Evaluation of a Modified EUCAST Fragmented-Mycelium Inoculum Method forIn VitroSusceptibility Testing of Dermatophytes and the Activity of Novel Antifungal Agents
2015 ◽
Vol 59
(6)
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pp. 3675-3682
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Keyword(s):
ABSTRACTFor antifungal susceptibility testing of nonsporulating or poorly sporulating dermatophytes, a fragmented-mycelium inoculum preparation method was established and compared to broth microdilution testing according to CLSI and EUCAST guidelines. Moreover, thein vitroactivity of new antifungal agents against dermatophytes was evaluated. Agreement between the mycelial inoculum method and the CLSI broth microdilution method was high (93% to 100%). Echinocandins (minimal effective concentration [MEC], ≤0.5 mg/liter) and posaconazole (MIC, ≤3.00 mg/liter) showed good activity against all tested dermatophytes.
2021 ◽
2000 ◽
Vol 44
(10)
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pp. 2752-2758
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2016 ◽
Vol 7
(1)
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pp. 11
2017 ◽
Vol 55
(6)
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pp. 1883-1893
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1994 ◽
Vol 32
(7)
◽
pp. 1625-1628
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1994 ◽
Vol 32
(8)
◽
pp. 1992-1996
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2019 ◽
Vol 7
(2)
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pp. 247-249