In Vitro Activities of a New Ketolide, ABT-773, against Multidrug-Resistant Gram-Positive Cocci
2001 ◽
Vol 45
(12)
◽
pp. 3640-3643
◽
Keyword(s):
ABSTRACT The in vitro activities of ABT-773 were evaluated against 324 strains of gram-positive bacteria, including multidrug-resistantStaphylococcus spp. and Enterococcus spp. ABT-773 had lower MIC ranges, MICs at which 50% of isolates are inhibited (MIC50s), and MIC90s than erythromycin or clindamycin for almost all isolates tested. The MICs of ABT-773 were also lower than those of quinupristin-dalfopristin (Q-D) for methicillin-susceptible Staphylococcus aureus,Rhodococcus spp., and Streptococcus spp., while the MICs of Q-D were lower than those of ABT-773 for methicillin-resistant S. aureus and Enterococcus faecium, including vancomycin-resistant isolates.
2005 ◽
Vol 49
(6)
◽
pp. 2498-2500
◽
2000 ◽
Vol 44
(12)
◽
pp. 3447-3450
◽
2002 ◽
Vol 46
(4)
◽
pp. 1108-1111
◽
2005 ◽
Vol 49
(9)
◽
pp. 3933-3936
◽
2007 ◽
Vol 26
(5)
◽
pp. 363-365
◽
2006 ◽
Vol 55
(4)
◽
pp. 407-415
◽