The Highly Conserved tRNAHis Guanylyltransferase Thg1p Interacts with the Origin Recognition Complex and Is Required for the G2/M Phase Transition in the Yeast Saccharomyces cerevisiae
Keyword(s):
M Phase
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ABSTRACT Here we show that the Saccharomyces cerevisiae tRNAHis guanylyltransferase Thg1p interacts with the origin recognition complex in vivo and in vitro and that overexpression of hemagglutinin-Thg1p selectively impedes growth of orc2-1(Ts) cells at the permissive temperature. Studies with conditional mutants indicate that Thg1p couples nuclear division and migration to cell budding and cytokinesis in yeast.
1996 ◽
Vol 16
(4)
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pp. 1805-1812
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1995 ◽
Vol 15
(11)
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pp. 5983-5990
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Keyword(s):
1990 ◽
Vol 10
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pp. 5679-5687
1992 ◽
Vol 12
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pp. 4215-4229
1995 ◽
Vol 15
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pp. 1999-2009
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1991 ◽
Vol 11
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pp. 2736-2743
1991 ◽
Vol 11
(5)
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pp. 2736-2743
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1995 ◽
Vol 128
(5)
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pp. 749-760
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