Interleukin-8 Secretion from Mycobacterium tuberculosis-Infected Monocytes Is Regulated by Protein Tyrosine Kinases but Not by ERK1/2 or p38 Mitogen-Activated Protein Kinases
2002 ◽
Vol 70
(8)
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pp. 4743-4746
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Keyword(s):
ABSTRACT Mycobacterium tuberculosis upregulates NF-κB binding and interleukin-8 (IL-8) gene expression and secretion in primary human monocytes. Inhibition of tyrosine protein kinases but not of ERK1/2 or p38 mitogen-activated protein kinases downregulates tuberculosis-induced IL-8 secretion. The inhibitor genistein decreased NF-κB nuclear translocation and IL-8 gene transcription in addition to acting on posttranscriptional processing.
2000 ◽
Vol 48
(3)
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pp. 255-264
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2007 ◽
Vol 7
(2)
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pp. 230-240
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2008 ◽
Vol 105
(5)
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pp. 654-660
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2012 ◽
Vol 207
(2)
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pp. 340-350
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1998 ◽
Vol 273
(25)
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pp. 15507-15513
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2013 ◽
Vol 34
(2)
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pp. 259-270
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2003 ◽
Vol 59
(4)
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pp. 945-954
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2004 ◽
Vol 72
(10)
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pp. 5832-5839
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