SarA of Staphylococcus aureus Binds to the sarA Promoter To Regulate Gene Expression
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Dnase I
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ABSTRACT The 375-bp sarA open reading frame is driven by three promoters, P1, P3, and P2. Using gel shift and DNase I footprinting assays, we found that SarA binds to two 26-bp sequences and one 31-bp sequence within the P1 and P3 promoters, respectively. Together with the results of transcription analyses, our data indicate that SarA binds to its own promoter to down-regulate sarA expression.
1999 ◽
Vol 73
(12)
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pp. 10519-10524
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2001 ◽
Vol 75
(20)
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pp. 10005-10013
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2005 ◽
Vol 73
(7)
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pp. 4391-4394
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