scholarly journals Relationship Between the Location of Autolysin, Cell Wall Synthesis, and the Development of Resistance to Cellular Autolysis in Streptococcus faecalis After Inhibition of Protein Synthesis

1970 ◽  
Vol 103 (2) ◽  
pp. 457-466 ◽  
Author(s):  
Harold M. Pooley ◽  
Gerald D. Shockman
1962 ◽  
Vol 237 (4) ◽  
pp. 1198-1202
Author(s):  
W. Grady Smith ◽  
Mary Newman ◽  
Franklin R. Leach ◽  
L.M. Henderson

1972 ◽  
Vol 25 (11) ◽  
pp. 679-680 ◽  
Author(s):  
EIRYO KITANAKA ◽  
KAZUYORI OCHIAI ◽  
YASUHISA HAMASU ◽  
MASAFUMI NAKAO ◽  
SHOZO NAKAZAWA

mSystems ◽  
2021 ◽  
Author(s):  
Raimo Franke ◽  
Heike Overwin ◽  
Susanne Häussler ◽  
Mark Brönstrup

Novel antibiotics are urgently needed to tackle the growing worldwide problem of antimicrobial resistance. Bacterial pathogens possess few privileged targets for a successful therapy: the majority of existing antibiotics as well as current candidates in development target the complex bacterial machinery for cell wall synthesis, protein synthesis, or DNA replication.


1978 ◽  
Vol 24 (5) ◽  
pp. 563-568 ◽  
Author(s):  
U. Singer ◽  
R. Röschenthaler

Ochratoxin A (OTA) added during the exponential growth phase at a concentration higher than 12 μg/ml caused autolysis of Bacillus subtilis. Optical density of cultures decreased, and at higher concentrations the cultures became sterile. Optimum OTA-induced lysis was about pH 5. At concentrations below 10 μg/ml, protein synthesis was inhibited more strongly than RNA synthesis. Cell wall synthesis was also strongly inhibited. A fraction extracted from the lysates had the property of a lysis inhibitor. The relevance of this fraction in respect to autolysis is discussed.


1972 ◽  
Vol 25 (8) ◽  
pp. 469-470 ◽  
Author(s):  
MASAFUMI NAKAO ◽  
EIRYO KITANAKA ◽  
KAZUYORI OCHIAI ◽  
SHOZO NAKAZAWA

1972 ◽  
Vol 16 (5) ◽  
pp. 403-413 ◽  
Author(s):  
Masafumi Nαkαo ◽  
Eiryo Kitanaka ◽  
Kazuyori Ochiai ◽  
Shozo Nakazawa

1972 ◽  
Vol 25 (1) ◽  
pp. 60-63 ◽  
Author(s):  
MASAFUMI NAKAO ◽  
EIRYO KITANAKA ◽  
KAZUYORI OCHIAI ◽  
SHOZO NAKAZAWA

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