Use of Coreceptors Other Than CCR5 by Non-Syncytium-Inducing Adult and Pediatric Isolates of Human Immunodeficiency Virus Type 1 Is Rare In Vitro
1998 ◽
Vol 72
(11)
◽
pp. 9337-9344
◽
Keyword(s):
ABSTRACT We have tested a panel of pediatric and adult human immunodeficiency virus type 1 (HIV-1) primary isolates for the ability to employ the following proteins as coreceptors during viral entry: CCR1, CCR2b, CCR3, CCR4, CCR5, CCR8, CXCR4, Bonzo, BOB, GPR1, V28, US28, and APJ. Most non-syncytium-inducing isolates could utilize only CCR5. All syncytium-inducing viruses used CXCR4, some also employed V28, and one (DH123) used CCR8 and APJ as well. A longitudinal series of HIV-1 subtype B isolates from an infected infant and its mother utilized Bonzo efficiently, as well as CCR5. The maternal isolates, which were syncytium inducing, also used CXCR4, CCR8, V28, and APJ.
2003 ◽
Vol 77
(7)
◽
pp. 4409-4414
◽
2002 ◽
Vol 76
(3)
◽
pp. 1015-1024
◽
2003 ◽
Vol 77
(1)
◽
pp. 291-300
◽
1998 ◽
Vol 9
(5)
◽
pp. 412-421
◽
2004 ◽
Vol 78
(13)
◽
pp. 7279-7283
◽
2001 ◽
Vol 75
(8)
◽
pp. 3916-3924
◽
2000 ◽
Vol 74
(17)
◽
pp. 7699-7707
◽
2011 ◽
Vol 55
(12)
◽
pp. 5723-5731
◽