RNA polymerase II transcription factors H4TF-1 and H4TF-2 require metal to bind specific DNA sequences.
1987 ◽
Vol 7
(12)
◽
pp. 4582-4584
◽
Keyword(s):
Specific DNA-binding and in vitro transcription activities of H4TF-1 and H4TF-2 are inactivated by chelating agents. Binding activity is restored by addition of Zn2+, and H4TF-2 is also reactivated by Fe2+. In contrast, preformed factor-DNA complexes are resistant to chelators. Therefore, metal ions are a required component of the H4TF-1 and H4TF-2 DNA-binding domains.
1987 ◽
Vol 7
(12)
◽
pp. 4582-4584
Keyword(s):
1993 ◽
Vol 13
(9)
◽
pp. 5702-5709
1993 ◽
Vol 13
(9)
◽
pp. 5702-5709
◽
2000 ◽
Vol 20
(6)
◽
pp. 2087-2097
◽
2005 ◽
Vol 79
(13)
◽
pp. 8661-8664
◽
2021 ◽
Vol 118
(35)
◽
pp. e2103895118
1992 ◽
Vol 12
(7)
◽
pp. 3006-3014
◽