Synthesis, structural characterization, and antifungal activity of Schiff bases and their transition metal mixed-ligand complexes

2006 ◽  
Vol 51 (1) ◽  
pp. 67-72 ◽  
Author(s):  
Hitesh M. Parekh ◽  
Saurabh R. Mehta ◽  
M. N. Patel
Keyword(s):  
Antifungal Activity ◽  
Transition Metal ◽  
Schiff Bases ◽  
Structural Characterization ◽  
Mixed Ligand ◽  
Mixed Ligand Complexes

scholarly journals New transition metal complexes with a pendent indole ring: insights into the antifungal activity and mode of action

RSC Advances ◽  
2019 ◽  
Vol 9 (27) ◽  
pp. 15151-15157 ◽  
Author(s):  
Ovas Ahmad Dar ◽  
Shabir Ahmad Lone ◽  
Manzoor Ahmad Malik ◽  
Mohmmad Younus Wani ◽  
Aijaz Ahmad ◽  
...  
Keyword(s):  
Antifungal Activity ◽  
Transition Metal ◽  
Metal Complexes ◽  
Transition Metal Complexes ◽  
Proton Pump ◽  
Mode Of Action ◽  
Mixed Ligand ◽  
Mixed Ligand Complexes ◽  
Indole Ring ◽  
Significant Proton

Mixed ligand complexes containing a pendent indole showed significant proton pump ATPase targeted antifungal activity.

Antimicrobial and Toxicological Studies of Mixed Ligand Transition Metal Complexes of Schiff Bases

2002 ◽  
Vol 2 (12) ◽  
pp. 797-799 ◽  
Author(s):  
M. Saidul Islam . ◽  
M. Akhter Farooque . ◽  
M.A.K. Bodruddoza . ◽  
M. Ashik Mosaddik . ◽  
M. Shahidul Alam .
Keyword(s):  
Transition Metal ◽  
Metal Complexes ◽  
Schiff Bases ◽  
Transition Metal Complexes ◽  
Mixed Ligand ◽  
Toxicological Studies

scholarly journals Studies on Antibacterial and Antifungal Activities and Minimum Inhibitory Concentrations of Mixed Ligand Transition Metal Complexes of Dibasic Acids as Primary and Heterocyclic Bases as Secondary Ligands

1970 ◽  
Vol 46 (3) ◽  
pp. 365-368 ◽  
Author(s):  
MA Akbor ◽  
MS Islam ◽  
N Akhter ◽  
S Ahmed ◽  
S Siraj
Keyword(s):  
Antifungal Activity ◽  
Transition Metal ◽  
Metal Complexes ◽  
Transition Metal Complexes ◽  
Mixed Ligand ◽  
Diffusion Method ◽  
Antifungal Activities ◽  
Minimum Inhibitory Concentrations ◽  
Antibacterial And Antifungal Activities ◽  
Antibacterial And Antifungal

Mixed ligand (diphenic/ adipic as primary Ligand and quinoline / 8 - hydroxyquinoline as secondary) transition metal complexes of Cobalt (II), Cupper (II), Rhodium (III) and Platinum (IV) ions were synthesized and characterized. Their antibacterial activities against ten bacteria had been evaluated by the disc diffusion method,whilst their antifungal activities against two fungi had been also evaluated by the same method. Minimum inhibitory concentrations (MIC) had been evaluated against six bacteria. The MIC of the complexes against Shigella dysenteriae, Samonella typhi, Streptococcus-β-haemolyticus and Bacillus megaterium were 32 μg/ml; whilst Escherichia coli and Samonella typhi-A the MIC of Co (II) and Pt (IV) were 32μg/ml and those of Cu(II) and Rh(III) complexes were 64 μg/ml. It was found that Cobalt (II), Cupper (II) & Rhodium (III) complexes had pronounced antibacterial and antifungal activities. Platinum (IV) complex had moderate antibacterial and antifungal activity. These values indicate that these are active compounds. Key words: Mixed Ligand; Transition metal; Antimicrobial Activity; Antifungal Activity Minimum Inhibitory Concentrations (MIC) DOI: http://dx.doi.org/10.3329/bjsir.v46i3.9044 BJSIR 2011; 46(3): 365-368

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