Changes in the sensitivity of the central respiratory mechanism during a 21-h bed rest

AbstractTo explore the effectiveness of microgravity simulated by head-down bed rest (HDBR) and artificial gravity (AG) with exercise on lung function. Twenty-four volunteers were randomly divided into control and exercise countermeasure (CM) groups for 96 h of 6° HDBR. Comparisons of pulse rate, pulse oxygen saturation (SpO2) and lung function were made between these two groups at 0, 24, 48, 72, 96 h. Compared with the sitting position, inspiratory capacity and respiratory reserve volume were significantly higher than before HDBR (0° position) (P< 0.05). Vital capacity, expiratory reserve volume, forced vital capacity, forced expiratory volume in 1 s, forced inspiratory vital capacity, forced inspiratory volume in 1 s, forced expiratory flow at 25, 50 and 75%, maximal mid-expiratory flow and peak expiratory flow were all significantly lower than those before HDBR (P< 0.05). Neither control nor CM groups showed significant differences in the pulse rate, SpO2, pulmonary volume and pulmonary ventilation function over the HDBR observation time. Postural changes can lead to variation in lung volume and ventilation function, but a HDBR model induced no changes in pulmonary function and therefore should not be used to study AG CMs.

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Bed Rest for Hypertension in Pregnancy: Evidence is Weak

Family Practice News ◽

10.1016/s0300-7073(06)72535-x ◽

2006 ◽

Vol 36 (2) ◽

pp. 50

Author(s):

ROBERT FINN

Keyword(s):

Bed Rest ◽

Hypertension In Pregnancy ◽

In Pregnancy

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Delayed interval delivery of the second and third fetuses in multiple pregnancy triplet (Сase report)

HEALTH OF WOMAN ◽

10.15574/hw.2016.111.148 ◽

2016 ◽

pp. 148-152

Author(s):

Y. Dubossarskaya ◽

◽

L. Padalko ◽

L. Zakharchenko ◽

E. Savel’eva ◽

...

Keyword(s):

Preterm Delivery ◽

Multiple Pregnancy ◽

Bed Rest ◽

Perinatal Morbidity ◽

Perinatal Complications ◽

Triplet Pregnancy ◽

Satisfactory Condition ◽

Nulliparous Women ◽

Perinatal Center ◽

Delayed Interval Delivery

This article describes a clinical case of vaginal delivery in nulliparous women 24 years old delayed interval delivery of the second and third fetuses in spontaneous multiple pregnancy dichorionic triamniotic triplet in a tertiary perinatal center. After preterm delivery in 27+5 weeks of gestation the first fetus to reduce perinatal morbidity and mortality of two fetuses that are left in the uterus, with informed consent of the woman preterm delivery the second and third fetuses occurred at intervals of 38 days, in 33+1 weeks of gestation. Careful monitoring of the state of the mother and fetuses was conducted. To increase the interval between the birth of the first fetus and the second and the third fetuses, prevention of obstetric and perinatal complications used tocolysis, antibiotics, progesterone, the prevention of respiratory distress syndrome of the newborn by corticosteroids and bed rest. Three girls were born alive with a weight of 980, 1800 and 1950 grams correspondingly. Childbirth complicated second degree perineal laceration and retained portions of placenta and membranes, puerperal period was uneventful. After 1.5 months, all infants discharged with her mother in a satisfactory condition with a weight of more than 3000 grams. Key words: multiple pregnancy, triplet pregnancy, delayed interval delivery in triplet pregnancy, preterm delivery.

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Hippocampal changes and spatial cognition associated with 60 days of bed rest with and without exercise as a countermeasure

10.26226/morressier.5b31ec6a2afeeb001345ba5c ◽

2018 ◽

Author(s):

Katharina Brauns ◽

Anika Werner

Keyword(s):

Spatial Cognition ◽

Bed Rest

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The Bed Rest Avoidance Study

Case Medical Research ◽

10.31525/ct1-nct04006990 ◽

2019 ◽

Author(s):

Keyword(s):

Bed Rest

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Exercise Training as an Intervention to Improve Muscle Function and Recovery Following Bed Rest in Older Adults With Type 2 Diabetes

Case Medical Research ◽

10.31525/ct1-nct04057677 ◽

2019 ◽

Author(s):

Keyword(s):

Type 2 Diabetes ◽

Older Adults ◽

Exercise Training ◽

Muscle Function ◽

Bed Rest

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Bed Rest or Ambulation in the Initial Treatment of Patients With Acute Deep Vein Thrombosis or Pulmonary Embolism: Findings From the RIETE Registry

Yearbook of Vascular Surgery ◽

10.1016/s0749-4041(08)70604-3 ◽

2007 ◽

Vol 2007 ◽

pp. 348-349

Author(s):

G.L. Moneta

Keyword(s):

Pulmonary Embolism ◽

Deep Vein Thrombosis ◽

Initial Treatment ◽

Bed Rest ◽

Vein Thrombosis ◽

Acute Deep Vein Thrombosis ◽

Deep Vein

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690 Intracranial Hypotension Due to CSF Leak Secondary to Ventral Thoracic Osteophyte Complex: Resolution After Transdural Thoracic Discectomy and Dural Repair

British Journal of Surgery ◽

10.1093/bjs/znab134.313 ◽

2021 ◽

Vol 108 (Supplement_2) ◽

Author(s):

B Kewlani ◽

I Hussain ◽

J Greenfield

Keyword(s):

Intracranial Hypotension ◽

Spontaneous Intracranial Hypotension ◽

Bed Rest ◽

Structural Defects ◽

Csf Leak ◽

History Of ◽

Surgical Cure ◽

Thoracic Discectomy ◽

Herniated Discs

Abstract The hallmark symptom of spontaneous intracranial hypotension (SIH) is orthostatic headaches which manifests secondary to cerebrospinal fluid (CSF) hypovolaemia. Well-recognised aetiologies include trauma which includes procedures such as lumbar punctures and spinal surgery. More recently, structural defects such as bony osteophytes and calcified or herniated discs have been attributed to mechanically compromising dural integrity consequently resulting in CSF leak and symptom manifestation. A thorough literature review noted only a handful of such cases. We report the case of a thirty-two-year-old Asian female who presented with a one-month history of new-onset progressively worsening orthostatic headaches. Workup included MRI of the thoracic spine which revealed an epidural collection of CSF consequently prompting a dynamic CT-myelogram of the spine which not only helped to confirm severe cerebral hypotension but also suggested the underlying cause as being a dorsally projecting osteophyte-complex at level T2-3. Conservative and medical management including bed rest, analgesia, mechanical compression, and epidural blood patches failed to alleviate symptoms and a permanent surgical cure was eventually sought. The surgery involved T2-T3 laminectomy and osteophytectomy and at a 3-month follow-up, complete resolution of symptoms was noted.

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