Investigation of erythrocyte membrane damage under the action of γ radiation in a wide dose range using electroporation

2008 ◽  
Vol 5 (2) ◽  
pp. 127-130 ◽  
Author(s):  
A. P. Kozlov ◽  
E. A. Krasavin ◽  
A. V. Boreyko ◽  
A. P. Chernyaev ◽  
P. Yu. Alekseeva ◽  
...  
Keyword(s):  
Erythrocyte Membrane ◽  
Dose Range ◽  
Membrane Damage ◽  
Γ Radiation

Efficient monitoring of dosimetric behaviour for copper nanoparticles through studying its optical properties

2019 ◽  
Vol 107 (6) ◽  
pp. 523-529 ◽  
Author(s):  
Mohamad Bekhit ◽  
Asmaa Sobhy ◽  
Zakaria I. Ali ◽  
Sameh M. Gafar
Keyword(s):  
Copper Nanoparticles ◽  
Metal Ion ◽  
Copper Ions ◽  
Dose Range ◽  
Ion Concentration ◽  
Nanocomposite Films ◽  
Poly Vinyl Alcohol ◽  
High Dose ◽  
Γ Irradiation ◽  
Γ Radiation

Abstract A novel high-dose dosimeter based on γ radiation reduction of copper ions and formation of copper metal inside polymer matrix were investigated. γ radiation induced synthesis of copper nanoparticles (CuNPs) in poly vinyl alcohol films were studied by UV-Visible Spectrophotometer, X-ray diffraction (XRD) and Fourier Transform Infrared Spectroscopy (FTIR). The optical absorption spectra showed that the Cu/PVA nanocomposite films have surface plasmon resonance (SPR) of copper nanoparticles which depending on irradiation doses. Upon γ irradiation these films turns its color from faint blue to deep reddish brown depending on metal ion concentration. The XRD pattern and FTIR spectrum confirm the formation of the CuNPs. The response of Cu/PVA nanocomposite dosimeters depends on both the irradiation doses and concentration of copper precursor. The dose range for these films was from 50 to 650 kGy, revealing its important applications for high dose dosimetry. Cu/PVA nanocomposites films exhibit good post-irradiation stability in dark and light.

The effects of the caffeic acid phenethyl ester(CAPE) on erythrocyte membrane damage after hind limb ischaemia–reperfusion

2004 ◽  
Vol 22 (5) ◽  
pp. 287-290 ◽  
Author(s):  
Lülüfer Tamer ◽  
Nehir Sucu ◽  
Bahadır Ercan ◽  
Ali Ünlü ◽  
Mukadder Çalıkoğlu ◽  
...  
Keyword(s):  
Caffeic Acid ◽  
Erythrocyte Membrane ◽  
Hind Limb ◽  
Membrane Damage ◽  
Caffeic Acid Phenethyl Ester ◽  
Limb Ischaemia ◽  
Ischaemia Reperfusion

scholarly journals Toxic effect of puromycin on erythrocyte membranes which is unrelated to inhibition of protein synthesis

Blood ◽  
1975 ◽  
Vol 45 (1) ◽  
pp. 21-27 ◽  
Author(s):  
ER Burka ◽  
SK Ballas ◽  
SM Sabesin
Keyword(s):  
Protein Synthesis ◽  
Cell Membrane ◽  
Toxic Effect ◽  
Erythrocyte Membrane ◽  
Membrane Damage ◽  
Erythrocyte Membranes ◽  
Erythroid Cell ◽  
Ultrastructural Changes ◽  
Direct Toxic Effect ◽  
Increased Susceptibility

Abstract Exposure of rabbit or human erythrocytes to concentrations of puromycin as low as 7 x 10(-4)M for 2 hr causes damage to the cell membrane, as evidenced by increased susceptibility of the cells to hyposmotic lysis, increased cell rigidity, and ultrastructural changes consistent with severe membrane damage. Puromycin causes a concentration-dependent internalization of the erythrocyte membrane, resulting in vacuolization of the cells, at concentrations between 7 x 10(-4) M and 10(-2) M. Since the erythrocyte does not synthesize protein, the data indicate that puromycin has a direct toxic effect on erythroid cell membranes which is unrelated to its action in inhibiting the synthesis of protein.

scholarly journals Redox-active biflavonoids from Garcinia brasiliensis as inhibitors of neutrophil oxidative burst and human erythrocyte membrane damage

2015 ◽  
Vol 174 ◽  
pp. 410-418 ◽  
Author(s):  
Phanuel Saroni Arwa ◽  
Maria Luiza Zeraik ◽  
Valdecir Farias Ximenes ◽  
Luiz Marcos da Fonseca ◽  
Vanderlan da Silva Bolzani ◽  
...  
Keyword(s):  
Erythrocyte Membrane ◽  
Oxidative Burst ◽  
Human Erythrocyte ◽  
Membrane Damage ◽  
Human Erythrocyte Membrane ◽  
Redox Active ◽  
Neutrophil Oxidative Burst

scholarly journals Toxic effect of puromycin on erythrocyte membranes which is unrelated to inhibition of protein synthesis

Blood ◽  
1975 ◽  
Vol 45 (1) ◽  
pp. 21-27
Author(s):  
ER Burka ◽  
SK Ballas ◽  
SM Sabesin
Keyword(s):  
Protein Synthesis ◽  
Cell Membrane ◽  
Toxic Effect ◽  
Erythrocyte Membrane ◽  
Membrane Damage ◽  
Erythrocyte Membranes ◽  
Erythroid Cell ◽  
Ultrastructural Changes ◽  
Direct Toxic Effect ◽  
Increased Susceptibility

Exposure of rabbit or human erythrocytes to concentrations of puromycin as low as 7 x 10(-4)M for 2 hr causes damage to the cell membrane, as evidenced by increased susceptibility of the cells to hyposmotic lysis, increased cell rigidity, and ultrastructural changes consistent with severe membrane damage. Puromycin causes a concentration-dependent internalization of the erythrocyte membrane, resulting in vacuolization of the cells, at concentrations between 7 x 10(-4) M and 10(-2) M. Since the erythrocyte does not synthesize protein, the data indicate that puromycin has a direct toxic effect on erythroid cell membranes which is unrelated to its action in inhibiting the synthesis of protein.

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