Hydroboration of 1,4-diallylpiperazine

1985 ◽  
Vol 50 (10) ◽  
pp. 2275-2283 ◽  
Author(s):  
Stanislav Kafka ◽  
Miloslav Ferles
Keyword(s):  
Mass Spectrometry ◽  
Hydrogen Peroxide ◽  
Liquid Chromatography ◽  
Hydrochloric Acid ◽  
Sodium Borohydride ◽  
Gas Liquid Chromatography ◽  
Alkaline Hydrogen Peroxide ◽  
Subsequent Oxidation

Hydroboration of 1,4-diallylpiperazine (I) with triethylamine-borane afforded 5,8-diaza-1,9-diboradispiro[4,2,4,2]tetradecane (II). 1,4-Diallylpiperazine dihydrochloride reacted with sodium borohydride to give 1,4-diallylpiperazine-diborane (V). Ethanolysis of II furnished 1,4-bis(3-diethoxyborylpropyl)piperazine (IV). The products of hydroboration of I were subjected to hydrolysis with hydrochloric acid and subsequent oxidation with alkaline hydrogen peroxide and the obtained mixtures were analysed by gas-liquid chromatography and mass spectrometry.

Concentrations of non-glucose polyols in serum and cerebrospinal fluid from apparently healthy adults and children.

1984 ◽  
Vol 30 (2) ◽  
pp. 188-191 ◽  
Author(s):  
S Yoshioka ◽  
S Saitoh ◽  
S Seki ◽  
K Seki
Keyword(s):  
Mass Spectrometry ◽  
Cerebrospinal Fluid ◽  
Liquid Chromatography ◽  
Healthy Subjects ◽  
Metabolic Diseases ◽  
Gas Liquid Chromatography ◽  
Liquid Chromatography Mass Spectrometry ◽  
Adults And Children ◽  
Healthy Persons ◽  
Apparently Healthy

Abstract Six non-glucose polyols--mannose, fructose, 1-deoxyglucose, mannitol, glucitol, and inositol--were identified and evaluated in human serum and cerebrospinal fluid by gas-liquid chromatography and by gas-liquid chromatography/mass spectrometry. Concentrations of fructose, mannose, and inositol in the serum of healthy persons or children without metabolic diseases varied with age, as already reported for 1-deoxyglucose. Fructose, inositol, and glucitol concentrations in cerebrospinal fluid significantly exceeded those in serum. The method described here for determining polyols and for evaluating polyol patterns in serum, as well as the resulting data on children and healthy subjects, should be useful in investigations of the clinical and physiological significance of polyols.

scholarly journals Oxidized plant sterols in human serum and lipid infusions as measured by combined gas-liquid chromatography-mass spectrometry

2001 ◽  
Vol 42 (12) ◽  
pp. 2030-2038 ◽  
Author(s):  
Jogchum Plat ◽  
Harald Brzezinka ◽  
Dieter Lütjohann ◽  
Ronald P. Mensink ◽  
Klaus von Bergmann
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Human Serum ◽  
Plant Sterols ◽  
Gas Liquid Chromatography ◽  
Liquid Chromatography Mass Spectrometry ◽  
Chromatography Mass Spectrometry

scholarly journals Gas-liquid chromatography-mass spectrometry of trimethylsilyl ethers of bile alcohols.

1978 ◽  
Vol 19 (8) ◽  
pp. 956-966
Author(s):  
G S Tint ◽  
B Dayal ◽  
A K Batta ◽  
S Shefer ◽  
F W Cheng ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Gas Liquid Chromatography ◽  
Liquid Chromatography Mass Spectrometry ◽  
Chromatography Mass Spectrometry ◽  
Trimethylsilyl Ethers
Sign in / Sign up

Export Citation Format

Share Document