AB0384 Comparison of the Effect of Denosumab and Alendronate on Bone Density and Microarchitecture at the 2ND Metacarpal Head in Rheumatoid Arthritis Females with Low Bone Mass by High- Resolution Peripheral Quantitative Computer Tomography: A Randomized Controlled Pilot Trial

2015 ◽  
Vol 74 (Suppl 2) ◽  
pp. 1021.2-1021
Author(s):  
P. Wong ◽  
T.Y. Zhu ◽  
L. Qin ◽  
E.K. Li ◽  
L.-S. Tam
Keyword(s):  
Rheumatoid Arthritis ◽  
High Resolution ◽  
Bone Density ◽  
Bone Mass ◽  
Computer Tomography ◽  
Pilot Trial ◽  
Low Bone Mass ◽  
Metacarpal Head ◽  
Randomized Controlled ◽  
Quantitative Computer Tomography

scholarly journals Investigation of the bone density in multiple sclerosis

2008 ◽  
Vol 7 (2) ◽  
pp. 46-51
Author(s):  
O. S. Dranichnikova ◽  
V. D. Zavadovskaya ◽  
V. M. Alifirova
Keyword(s):  
Physical Activity ◽  
Multiple Sclerosis ◽  
Bone Density ◽  
Bone Formation ◽  
Bone Mass ◽  
Computer Tomography ◽  
Dramatic Decrease ◽  
Disability Status ◽  
Common Opinion ◽  
Therapy Sessions

A number of investigations revealed a problem of osteopenic syndrome in patients with multiple sclerosis but there is no common opinion concerning factors which lead to its development. We observed 65 patients with multiple sclerosis with various type of its course and disability status of several degree based upon EDSS scale. Ultrasound osteometry of the calcaneus, computer tomography of QCT of L1—L3 vertebras were performed, serum crosslaps, N-MID osteocalcin were used. Decreased bone density, injured bone microarchitectonics and suppression of bone formation and resorption, which were correlated EDSS were found. Correlations with other factors (growth, weight, gender, and number of steroid therapy sessions ) for these parameters was not revealed. This allowed to conclude that the main reason of decreased bone mass in patients with multiple sclerosis is the dramatic decrease in physical activity.

scholarly journals Efficacy of a Rheumatoid Arthritis-Specific Smoking Cessation Program: A Randomized Controlled Pilot Trial

2016 ◽  
Vol 69 (1) ◽  
pp. 28-37 ◽  
Author(s):  
Pip Aimer ◽  
Gareth J. Treharne ◽  
Simon Stebbings ◽  
Chris Frampton ◽  
Vicky Cameron ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Smoking Cessation ◽  
Pilot Trial ◽  
Smoking Cessation Program ◽  
Randomized Controlled

Effect of denosumab on bone density and turnover in postmenopausal women with low bone mass after long-term continued, discontinued, and restarting of therapy: A randomized blinded phase 2 clinical trial

Bone ◽  
2008 ◽  
Vol 43 (2) ◽  
pp. 222-229 ◽  
Author(s):  
Paul D. Miller ◽  
Michael A. Bolognese ◽  
E. Michael Lewiecki ◽  
Michael R. McClung ◽  
Beiying Ding ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Bone Density ◽  
Bone Mass ◽  
Postmenopausal Women ◽  
Phase 2 ◽  
Low Bone Mass ◽  
Phase 2 Clinical Trial
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