AB0324 Is low serum vitamin d level associated with increased neuropathic pain in rheumatoid arthritis patients? a cross-sectional study

Abstract Background: Low serum vitamin D concentrations have been reported to be associated with an increased risk of non-alcoholic fatty liver disease (NAFLD). However, whether slim or obese people show a similar association between vitamin D and NAFLD remains speculative. This study aimed to explore the relationship between serum vitamin D concentrations and NAFLD in lean and obese Chinese adults.Methods: This cross-sectional study included 2538 participants (1360 men and 1178 women) who underwent their health checkups at the First Affiliated Hospital of Zhejiang University School of Medicine in 2019. NAFLD was diagnosed by liver ultrasound excluding other causes. The association of serum vitamin D concentrations with NAFLD was analyzed in lean and obese participants.Results: The overall prevalence of NAFLD was 33.61% (13.10% in lean and 53.32% in obese) in this study population. The serum vitamin D levels of obese NAFLD patients were lower than that of the obese NAFLD-free controls. However, the serum vitamin D levels of lean NAFLD patients were comparable to that of the lean NAFLD-free controls. Serum vitamin D levels were negatively correlated with the prevalence of NAFLD in obese but not lean participants. Serum vitamin D levels were independently associated with the risk of NAFLD in obese participants, with an adjusted odd ratio (95% CI) of 0.986 (0.979–0.992). However, the serum vitamin D levels were not related to the risk of NAFLD in lean participants.Conclusions: Low serum vitamin D levels are associated with NAFLD in obese but not lean participants.

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Low serum vitamin D concentrations are associated with obese but not lean NAFLD: a cross-sectional study

10.21203/rs.3.rs-74825/v2 ◽

2021 ◽

Author(s):

Qinqiu Wang ◽

Xiao-ying Shi ◽

Jinghua Wang ◽

Juanwen Zhang ◽

Cheng-Fu Xu

Keyword(s):

Vitamin D ◽

Serum Vitamin ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Alcoholic Fatty Liver ◽

Serum Vitamin D ◽

Vitamin D Levels ◽

Lean Nafld ◽

Low Serum

Abstract Background: A low serum vitamin D concentration has been reported to be associated with an increased risk of non-alcoholic fatty liver disease (NAFLD); however, whether lean or obese individuals show a similar association between vitamin D and NAFLD remains speculative. This study aimed to explore the relationship between serum vitamin D concentration and NAFLD in lean and obese Chinese adults.Methods: This cross-sectional study included 2538 participants (1360 men and 1178 women) who underwent health checkups at the First Affiliated Hospital, Zhejiang University School of Medicine in 2019. NAFLD was diagnosed by liver ultrasound excluding other causes. The association of serum vitamin D concentration with NAFLD was analyzed in lean and obese participants.Results: The overall prevalence of NAFLD was 33.61% (13.10% in lean and 53.32% in obese) in this study population. The serum vitamin D levels of obese NAFLD patients were lower than those of obese NAFLD-free controls. However, the serum vitamin D levels of lean NAFLD patients were comparable to those of lean NAFLD-free controls. Serum vitamin D level was negatively correlated with the prevalence of NAFLD in obese but not lean participants. Serum vitamin D level was independently associated with the risk of NAFLD in obese participants, with an adjusted odds ratio (95% CI) of 0.987 (0.981–0.993). However, serum vitamin D level was not related to the risk of NAFLD in lean participants.Conclusions: A low serum vitamin D level is associated with NAFLD in obese but not lean participants.

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Serum vitamin D concentrations are associated with obese but not lean NAFLD: a cross-sectional study

10.21203/rs.3.rs-58859/v1 ◽

2020 ◽

Author(s):

Qinqiu Wang ◽

Xiaoyin Shi ◽

Jinghua Wang ◽

Juanwen Zhang ◽

Cheng-Fu Xu

Keyword(s):

Vitamin D ◽

Serum Vitamin ◽

Cross Sectional Study ◽

Sectional Study ◽

Obese People ◽

Cross Sectional ◽

Serum Vitamin D ◽

Vitamin D Levels ◽

Lean Nafld ◽

Low Serum

Abstract Background: Low serum vitamin D concentrations have been reported to be associated with an increased risk of non-alcoholic fatty liver disease (NAFLD). However, whether slim or obese people show a similar association between vitamin D and NAFLD remains speculative. This study aimed to explore the relationship between serum vitamin D concentrations and NAFLD in lean and obese Chinese adults.Methods: This cross-sectional study included 2538 participants (1360 men and 1178 women) who underwent their health checkups at the First Affiliated Hospital of Zhejiang University School of Medicine in 2019. NAFLD was diagnosed by liver ultrasound excluding other causes. The association of serum vitamin D concentrations with NAFLD was analyzed in lean and obese participants.Results: The overall prevalence of NAFLD was 33.61% (13.10% in lean and 53.32% in obese) in this study population. The serum vitamin D levels of obese NAFLD patients were lower than that of the obese NAFLD-free controls. However, the serum vitamin D levels of lean NAFLD patients were comparable to that of the lean NAFLD-free controls. Serum vitamin D levels were negatively correlated with the prevalence of NAFLD in obese but not lean participants. Serum vitamin D levels were independently associated with the risk of NAFLD in obese participants, with an adjusted odd ratio (95% CI) of 0.986 (0.979–0.992). However, the serum vitamin D levels were not related to the risk of NAFLD in lean participants.Conclusions: Low serum vitamin D levels are associated with NAFLD in obese but not lean participants.

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Low serum vitamin D concentrations are associated with obese but not lean NAFLD: a cross-sectional study

Nutrition Journal ◽

10.1186/s12937-021-00690-9 ◽

2021 ◽

Vol 20 (1) ◽

Author(s):

Qinqiu Wang ◽

Xiaoying Shi ◽

Jinghua Wang ◽

Juanwen Zhang ◽

Chengfu Xu

Keyword(s):

Vitamin D ◽

Serum Vitamin ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Alcoholic Fatty Liver ◽

Serum Vitamin D ◽

Vitamin D Levels ◽

Lean Nafld ◽

Low Serum

Abstract Background A low serum vitamin D concentration has been reported to be associated with an increased risk of non-alcoholic fatty liver disease (NAFLD); however, whether lean or obese individuals show a similar association between vitamin D and NAFLD remains speculative. This study aimed to explore the relationship between serum vitamin D concentration and NAFLD in lean and obese Chinese adults. Methods This cross-sectional study included 2538 participants (1360 men and 1178 women) who underwent health checkups at the First Affiliated Hospital, Zhejiang University School of Medicine in 2019. NAFLD was diagnosed by liver ultrasound excluding other causes. The association of serum vitamin D concentration with NAFLD was analyzed in lean and obese participants. Results The overall prevalence of NAFLD was 33.61% (13.10% in lean and 53.32% in obese) in this study population. The serum vitamin D levels of obese NAFLD patients were lower than those of obese NAFLD-free controls. However, the serum vitamin D levels of lean NAFLD patients were comparable to those of lean NAFLD-free controls. Serum vitamin D level was negatively correlated with the prevalence of NAFLD in obese but not lean participants. Serum vitamin D level was independently associated with the risk of NAFLD in obese participants, with an adjusted odds ratio (95% CI) of 0.987 (0.981–0.993). However, serum vitamin D level was not related to the risk of NAFLD in lean participants. Conclusions A low serum vitamin D level is associated with NAFLD in obese but not lean participants.

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Evaluation and comparison of serum vitamin D and calcium levels in periodontally healthy, chronic gingivitis and chronic periodontitis in patients with and without diabetes mellitus – a cross-sectional study

Acta Odontologica Scandinavica ◽

10.1080/00016357.2019.1623910 ◽

2019 ◽

Vol 77 (8) ◽

pp. 592-599 ◽

Cited By ~ 7

Author(s):

Anshuka A. Agrawal ◽

Abhay P. Kolte ◽

Rajashri A. Kolte ◽

Suresh Chari ◽

Madhur Gupta ◽

...

Keyword(s):

Diabetes Mellitus ◽

Vitamin D ◽

Chronic Periodontitis ◽

Serum Vitamin ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Serum Vitamin D

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Comparison of Vitamin D Levels, Bone Metabolic Marker Levels, and Bone Mineral Density among Patients with Thyroid Disease: A Cross-Sectional Study

Diagnostics ◽

10.3390/diagnostics10121075 ◽

2020 ◽

Vol 10 (12) ◽

pp. 1075

Author(s):

Masliza Hanuni Mat Ali ◽

Tuan Salwani Tuan Ismail ◽

Wan Norlina Wan Azman ◽

Najib Majdi Yaacob ◽

Norhayati Yahaya ◽

...

Keyword(s):

Vitamin D ◽

Serum Vitamin ◽

Cross Sectional Study ◽

Thyroid Diseases ◽

Z Score ◽

Sectional Study ◽

Mineral Density ◽

Cross Sectional ◽

Serum Vitamin D ◽

Vitamin D Levels

Thyroid hormones have a catabolic effect on bone homeostasis. Hence, this study aimed to evaluate serum vitamin D, calcium, and phosphate and bone marker levels and bone mineral density (BMD) among patients with different thyroid diseases. This cross-sectional study included patients with underlying thyroid diseases (n = 64, hyperthyroid; n = 53 euthyroid; n = 18, hypothyroid) and healthy controls (n = 64). BMD was assessed using z-score and left hip and lumbar bone density (g/cm2). The results showed that the mean serum vitamin D Levels of all groups was low (<50 nmol/L). Thyroid patients had higher serum vitamin D levels than healthy controls. All groups had normal serum calcium and phosphate levels. The carboxy terminal collagen crosslink and procollagen type I N-terminal propeptide levels were high in hyperthyroid patients and low in hypothyroid patients. The z-score for hip and spine did not significantly differ between thyroid patients and control groups. The hip bone density was remarkably low in the hyperthyroid group. In conclusion, this study showed no correlation between serum 25(OH)D levels and thyroid diseases. The bone markers showed a difference between thyroid groups with no significant difference in BMD.

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