AB0151 EXPRESSION OF ANXIETY AND DEPRESSION IN PATIENTS WITH ANKYLOSING SPONDILITE DEPENDING ON THE STATE OF THE AUTONOMIC NERVOUS SYSTEM AND INTENSITY OF THE PAIN SYNDROME

In recent decades, the shift in priority in the treatment of patients with pulmonary granulomatosis in the direction of etiotropic therapy and reduced attention to the state of the macroorganism led to a decrease in the effectiveness of treatment. In modern conditions, when carrying out complex therapy for patients with tuberculosis and sarcoidosis, insufficient attention is paid to the state and dynamics of adaptation, resistance, homeostasis and reactivity of the organism. At the same time, the dynamics of these processes in patients is insignificant, the homeostatic balance of the organism is not restored, and the reactivity of the organism remains at the pathological level, with the predominance of paradoxical, hyporeactive and areactive types. This is due to the continuing influence on the regulatory centers of the vegetative system of not diagnosed, latent, ongoing tuberculosis intoxication. Undetected specific intoxication causes in patients activation of the sympathetic department, suppression of parasympathetic and development of dysfunction of the autonomic nervous system. Its dysfunction leads to a decrease in vascular supply of the organism, a high tension of anabolic processes, and a further change in the functional activity of both parts of this system when pathology develops. In addition, the emergence of vegetative dysfunction leads to a high consumption of plastic materials, energy resources, a decrease in the functional reserves of the body, a decrease and depletion of the body’s defense systems, its anti-inflammatory potential and the reactivity of the organism as a whole. These changes lead to an extension of the main course of treatment and the formation of expressed residual tubercular and sarcoidosis in the respiratory organs. To restore these disorders, it is necessary to carry out complex therapy with the inclusion of a personified appointment of activators of protective systems under the control of monitoring their effectiveness.

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The nature of the course of the retention period in adolescents after orthodontic treatment depending on the state of the autonomic nervous system

Kazan medical journal ◽

10.17816/kmj1563 ◽

2012 ◽

Vol 93 (4) ◽

pp. 651-653

Author(s):

D R Singatullina ◽

N Kh Khamitova

Keyword(s):

Nervous System ◽

Autonomic Nervous System ◽

Orthodontic Treatment ◽

Heart Rhythm ◽

The State ◽

Autonomic Reactivity ◽

Autonomic Tone ◽

Retention Period ◽

Autonomic Nervous ◽

Complete Adaptation

Aim. To study the condition of the autonomic nervous system in groups of adolescents in the period of retention after active orthodontic treatment with non-removable equipment. Methods. Examined were 100 adolescents aged 13-17 years in the period of retention after active orthodontic treatment. The baseline autonomic tone was assessed according to the combined table of sympathetic and parasympathetic reactions (Wayne A., 1981) in the modification of N.A. Belokon’ et al. (1986) for children and adolescents, taken into account were the heart rate, respiratory rate, systolic and diastolic blood pressure. In order to evaluate the adaptation of the organism used was a mathematical analysis of the heart rhythm (cardiointervalography), determined was the mode (Mo), the amplitude of the mode (AMo), and the variational span (ΔX). Results. Revealed were two groups of patients with different variants of the course of retention: favorable course without recurrence (53%) and unfavorable course with recurrences (47%). In the group of patients with recurrences cardiointervalography most frequently showed a asympaticotonic (41.7%) or hypersympaticotonic (58.3%) type of autonomic reactivity. In all patients of the group with recurrences noted was a disturbance of the adaptation processes. The state of adaptation is regarded as unsatisfactory in 72.6% of cases, as the complete adaptation failure - in 27.4%. Conclusion. A recurrence during the period of retention after active orthodontic treatment occurs significantly more frequently in the group of patients with high constraint and overload of the autonomic reactivity, with a mismatch of cardiac rhythm management processes, with a reduction of the adaptive capacity of the organism to the level of complete failure of adaptation; patients who have expressed sympathicotonia, are at risk for destructive periodontal disease and require special attention during the retention period.

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Peculiarities of vegetative provision and disorders of tolerance to exercise in children with endocrine and cardiac pathology

Reports of Vinnytsia National Medical University ◽

10.31393/reports-vnmedical-2020-24(4)-13 ◽

2020 ◽

Vol 24 (4) ◽

pp. 634-639

Author(s):

K. Shtrakh ◽

O. Tsiura ◽

L. Rak ◽

N. Shevchenko

Keyword(s):

Physical Activity ◽

Diabetes Mellitus ◽

Nervous System ◽

Autonomic Nervous System ◽

Arterial Hypertension ◽

Exercise Tolerance ◽

The State ◽

Cardiac Pathology ◽

Autonomic Nervous ◽

Autonomic Support

Annotation. The aim – to find out the features of autonomic support and exercise tolerance of the cardiovascular system in children with chronic non-infectious diseases, in the future will be able to improve the results of diagnosis and rehabilitation of patients, as well as differentially regulate the mode of the exercise regime for patients. The study included 58 children aged 10-17 years, with cardiac and endocrine pathology: group 1 – 23 children with endocrine pathology (type 1 diabetes mellitus), group 2 – 23 children with cardiac pathology (AH stages I-II). The study included clinical examinations, anthropometry, a questionnaire of physical activity by MAOFA, ECG, ultrasound examination of the heart and Rufier's test were performed. Assessment of the state of the autonomic nervous system was carried out using the Kerdo index and COT. Statistical analysis was performed using s/n program SPSS 17 4a 180844250981. It was found that there is a tendency to outstrip the normative values and increased body weight indicators in the examined children with chronic pathology of the endocrine and cardiovascular systems. According to the Rufier test, it was found that in the group of children with diabetes mellitus, 69.5±9.6% of the examined had low results. Among children with hypertension, 30.7±10.4% of the test indicators were regarded as weak, and in 26.9±5.8% – unsatisfactory. The results of Rufier's test were significantly lower in children with endocrine pathology, both in comparison with the group of children with cardiac pathology (p<0.05) and with the control group (p≤0.001). In 70.0±15.3% of cases, weak and unsatisfactory indicators of the Ruffier test were observed against the background of hyperdiastolic autonomic support. In physically nonactive adolescents, asympathicotonic and hyperdiastolic types of COT were observed. Thus, almost 70% of children with diabetes mellitus and 57% of children with arterial hypertension have reduced exercise tolerance. This is associated with hyperdiastolic autonomic support. Physical activity has a positive effect on the state of the autonomic nervous system in children with arterial hypertension and diabetes mellitus.

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Small Fiber Polyneuropathy May Be a Nexus Between Autonomic Nervous System Dysregulation and Pain in Interstitial Cystitis/Bladder Pain Syndrome

Frontiers in Pain Research ◽

10.3389/fpain.2021.810809 ◽

2022 ◽

Vol 2 ◽

Author(s):

Dylan T. Wolff ◽

Stephen J. Walker

Keyword(s):

Nervous System ◽

Autonomic Nervous System ◽

Interstitial Cystitis ◽

Sympathetic Innervation ◽

Pain Syndrome ◽

The United States ◽

Bladder Pain Syndrome ◽

Bladder Pain ◽

Autonomic Nervous ◽

Small Fiber

Interstitial cystitis/bladder pain syndrome (IC/BPS) is a highly heterogeneous chronic and debilitating condition which effects millions of women and men in the United States. While primarily defined by urinary symptoms and pain perceived to be emanating from the bladder, IC/BPS patients frequently have co-occurring conditions and symptoms, many of which affect diverse body systems related to autonomic nervous system function. The impact on the autonomic system appears to stem from increased sympathetic innervation of the urinary tract, along with increased systemic sympathetic tone and decreased parasympathetic tone. Concurrent with these findings is evidence for destruction of peripheral sympathetic innervation to the sweat glands which may relate to small fiber polyneuropathy. It is unknown to what degree the wider alterations in autonomic function are also related to destruction/alterations in the small fibers carrying autonomic innervation. This potential nexus is an important point of investigation to better understand the unclarified pathophysiology of interstitial cystitis/bladder pain syndrome, the numerous co-occurring symptoms and syndromes, and for the identification of novel targeted therapeutic strategies.

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Prevalence of autonomic nervous system dysfunction in complex regional pain syndrome

Regional Anesthesia and Pain Medicine ◽

10.1136/rapm-2020-101644 ◽

2021 ◽

pp. rapm-2020-101644

Author(s):

Ho-Jin Lee ◽

Kang Hee Lee ◽

Jee Youn Moon ◽

Yong-Chul Kim

Keyword(s):

Nervous System ◽

Autonomic Nervous System ◽

Complex Regional Pain Syndrome ◽

Pain Syndrome ◽

Sympathetic Skin Response ◽

Binary Logistic Regression Analysis ◽

Nerve Blocks ◽

Autonomic Nervous System Dysfunction ◽

Clinical Criteria ◽

Autonomic Nervous

BackgroundWe aimed to investigate the prevalence of dysautonomia in complex regional pain syndrome (CRPS) via the combined autonomic nervous system (ANS) function tests, including the deep breathing test (DBT), orthostatic test (OST) and sympathetic skin response (SSR).MethodWe retrospectively examined 263 patients who underwent the combined ANS tests to evaluate CRPS between August 2013 and December 2016. Based on the Budapest clinical criteria, patients were stratified into confirmed-CRPS or suspected-CRPS groups. We performed binary logistic regression analysis using the inverse probability of treatment weighting to investigate the association between the tests and CRPS. Sensitivity and specificity were calculated to assess the diagnostic performance of the ANS tests for CRPS. We compared the results of these tests between the outcomes of sympathetic nerve blocks (SNBs).ResultsAmong 247 patients, finally included in this study, 199 patients (80.6%) were diagnosed with CRPS. Abnormal results of overall or each ANS function test showed significant associations with CRPS, excluding OST (overall abnormality: OR 2.44, 95% CI 1.51 to 3.95; p<0.001; DBT: OR 2.57, 95% CI 1.23 to 5.38, p=0.013; OST: OR 1.88, 95% CI 0.92 to 3.84, p=0.085; SSR: OR 2.71, 95% CI 1.38 to 5.32, p=0.004). However, their prevalence in CRPS and their sensitivities for CRPS were low (overall abnormality: 26.1%; each test: <15%). No significant association existed between dysautonomia and SNB outcomes.ConclusionDysautonomia, as evaluated using the combined ANS tests, were observed in a small portion of patients with CRPS. The diagnostic performances of these tests for CRPS were inadequate for clinical purposes.

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