AB1388-HPR TREATMENT ADHERENCE AMONG PATIENTS WITH INFLAMMATORY ARTHRITIDES TREATED WITH BDMARDS: AN OBSERVATIONAL STUDY USING I-CQR5 QUESTIONNAIRE AND THE ADMINISTRATIVE CLAIMS DATABASE

Abstract Background The inappropriate use of antimicrobials for acute infectious diarrhea is widespread and leads to the problem of antimicrobial resistance. To improve the use of antimicrobials, it is first necessary to understand the actual situation of diarrheal disease and to identify potential targets for intervention. This study aimed to investigate the recent epidemiological characteristics of and antimicrobial prescriptions for acute infectious diarrhea in Japan. Methods This was a retrospective observational study of outpatients aged 0–65 years, separated into children (age 0–17 years) and adults (age 18–65 years), diagnosed with acute infectious diarrhea, using the administrative claims database of the Japan Medical Data Center from 2013 to 2018. We evaluated the number of eligible visits/number of database registrants (defined as the visit rate). The analysis of the antimicrobial prescription rate was restricted to otherwise healthy individuals diagnosed with acute infectious diarrhea alone by excluding patients with multiple disease diagnoses and with medical backgrounds of chronic bowel diseases or immunocompromised conditions. We further classified them by diagnosis of bacterial or nonbacterial acute infectious diarrhea. Results The total number of eligible visits for acute infectious diarrhea was 2,600,065. The visit rate, calculated based on the number of eligible visits by database registrants, was higher in children (boys, 0.264; girls, 0.229) than in adults (men, 0.070; women, 0.079), with peaks in early summer and winter. The peaks for visits in adults lagged those of children. In total, 482,484 visits were analyzed to determine the antimicrobial prescription rate; 456,655 (94.6%) were diagnosed with nonbacterial acute infectious diarrhea. Compared with children (boys, 0.305; girls, 0.304), the antimicrobial prescription rate was higher in adults, and there were differences between sexes in adults (men, 0.465; women, 0.408). Fosfomycin and fluoroquinolone were most frequently used for nonbacterial acute infectious diarrhea in children (44.1%) and adults (50.3%), respectively. Conclusions These results revealed overprescription of antimicrobials for acute infectious diarrhea in this administrative claims database in Japan and contribute to the development of antimicrobial stewardship strategies and the identification of targets for efficiently reducing inappropriate antimicrobial use.

Download Full-text

Mortality and comorbidities in patients with multiple sclerosis compared with a population without multiple sclerosis: An observational study using the US Department of Defense administrative claims database

Multiple Sclerosis and Related Disorders ◽

10.1016/j.msard.2015.08.005 ◽

2015 ◽

Vol 4 (6) ◽

pp. 546-554 ◽

Cited By ~ 46

Author(s):

Gorana Capkun ◽

Frank Dahlke ◽

Raquel Lahoz ◽

Beth Nordstrom ◽

Hugh H Tilson ◽

...

Keyword(s):

Multiple Sclerosis ◽

Observational Study ◽

Department Of Defense ◽

Administrative Claims ◽

Claims Database ◽

The Us

Download Full-text

Trends In Healthcare Visits And Antimicrobial Prescriptions For Acute Infectious Diarrhea In Individuals Aged 65 Years Or Younger In Japan From 2013 to 2018 Based On Administrative Claims Database: A Retrospective Observational Study

10.21203/rs.3.rs-523296/v1 ◽

2021 ◽

Author(s):

Akane Ono ◽

Kensuke Aoyagi ◽

Yuichi Muraki ◽

Yusuke Asai ◽

Shinya Tsuzuki ◽

...

Keyword(s):

Observational Study ◽

Diarrheal Disease ◽

Retrospective Observational Study ◽

Administrative Claims ◽

Prescription Rate ◽

Infectious Diarrhea ◽

Claims Database ◽

Visit Rate ◽

Epidemiological Characteristics ◽

Antimicrobial Prescription

Abstract Background: The inappropriate use of antimicrobials for acute infectious diarrhea is widespread and leads to the problem of antimicrobial resistance. To improve the use of antimicrobials, it is first necessary to understand the actual situation of diarrheal disease and to identify potential targets for intervention. This study aimed to investigate the recent epidemiological characteristics of and antimicrobial prescriptions for acute infectious diarrhea in Japan.Methods: This was a retrospective observational study of outpatients aged 0–65 years, separated into children (age 0–17 years) and adults (age 18–65 years), diagnosed with acute infectious diarrhea, using the administrative claims database of the Japan Medical Data Center from 2013 to 2018. We evaluated the number of eligible visits/number of database registrants (defined as the visit rate). The analysis of the antimicrobial prescription rate was restricted to otherwise healthy individuals diagnosed with acute infectious diarrhea alone by excluding patients with multiple disease diagnoses and with medical backgrounds of chronic bowel diseases or immunocompromised conditions. We further classified them by diagnosis of bacterial or nonbacterial acute infectious diarrhea.Results: The total number of eligible visits for acute infectious diarrhea was 2,600,065. The visit rate, calculated based on the number of eligible visits by database registrants, was higher in children (boys, 0.264; girls, 0.229) than in adults (men, 0.070; women, 0.079), with peaks in early summer and winter. The peaks for visits in adults lagged those of children. In total, 482,484 visits were analyzed to determine the antimicrobial prescription rate; 456,655 (94.6%) were diagnosed with nonbacterial acute infectious diarrhea. Compared with children (boys, 0.305; girls, 0.304), the antimicrobial prescription rate was higher in adults, and there were differences between sexes in adults (men, 0.465; women, 0.408). Fosfomycin and fluoroquinolone were most frequently used for nonbacterial acute infectious diarrhea in children (44.1%) and adults (50.3%), respectively.Conclusions: These results revealed overprescription of antimicrobials for acute infectious diarrhea in this administrative claims database in Japan and contribute to the development of antimicrobial stewardship strategies and the identification of targets for efficiently reducing inappropriate antimicrobial use.

Download Full-text

Demographic and clinical characteristics of prevention-eligible patients with migraine in the US: A linked national survey and administrative claims database study

Current Medical Research and Opinion ◽

10.1080/03007995.2020.1865749 ◽

2020 ◽

pp. 1-1

Author(s):

Shonda A. Foster ◽

Bridget L. Balkaran ◽

M. Janelle Cambron-Mellott ◽

Karen Samaan ◽

Oksana Mason ◽

...

Keyword(s):

National Survey ◽

Clinical Characteristics ◽

Administrative Claims ◽

Claims Database ◽

Database Study ◽

The Us

Download Full-text

High baseline pain is associated with treatment adherence in persons diagnosed with thumb base osteoarthritis: an observational study

Journal of Hand Therapy ◽

10.1016/j.jht.2021.04.024 ◽

2021 ◽

Author(s):

Vicky Duong ◽

Philippa JA Nicolson ◽

Sarah R Robbins ◽

Leticia A Deveza ◽

Anne Wajon ◽

...

Keyword(s):

Observational Study ◽

Treatment Adherence ◽

High Baseline

Download Full-text

Long-term outcomes in patients with schizophrenia treated with risperidone long-acting injection or oral antipsychotics in Spain: Results from the electronic Schizophrenia Treatment Adherence Registry (e-STAR)

European Psychiatry ◽

10.1016/j.eurpsy.2008.12.002 ◽

2009 ◽

Vol 24 (5) ◽

pp. 287-296 ◽

Cited By ~ 95

Author(s):

J.M. Olivares ◽

A. Rodriguez-Morales ◽

J. Diels ◽

M. Povey ◽

A. Jacobs ◽

...

Keyword(s):

Observational Study ◽

Treatment Adherence ◽

Prospective Observational Study ◽

Clinical Symptoms ◽

Retrospective Chart Review ◽

Treatment Retention ◽

Severity Scores ◽

Long Term Treatment ◽

Long Acting

AbstractBackgroundThe electronic Schizophrenia Treatment Adherence Registry (e-STAR) is a prospective, observational study of patients with schizophrenia designed to evaluate long-term treatment outcomes in routine clinical practice.MethodsParameters were assessed at baseline and at 3 month intervals for 2 years in patients initiated on risperidone long-acting injection (RLAI) (n = 1345) or a new oral antipsychotic (AP) (n = 277; 35.7% and 36.5% on risperidone and olanzapine, respectively) in Spain. Hospitalization prior to therapy was assessed by a retrospective chart review.ResultsAt 24 months, treatment retention (81.8% for RLAI versus 63.4% for oral APs, p < 0.0001) and reduction in Clinical Global Impression Severity scores (−1.14 for RLAI versus −0.94 for APs, p = 0.0165) were significantly higher with RLAI. Compared to the pre-switch period, RLAI patients had greater reductions in the number (reduction of 0.37 stays per patient versus 0.2, p < 0.05) and days (18.74 versus 13.02, p < 0.01) of hospitalizations at 24 months than oral AP patients.ConclusionsThis 2 year, prospective, observational study showed that, compared to oral antipsychotics, RLAI was associated with better treatment retention, greater improvement in clinical symptoms and functioning, and greater reduction in hospital stays and days in hospital in patients with schizophrenia. Improved treatment adherence, increased efficacy and reduced hospitalization with RLAI offer the opportunity of substantial therapeutic improvement in schizophrenia.

Download Full-text