SAT0276 CARDIAC MAGNETIC RESONANCE IMAGING IN PATIENTS WITH BEHCET’S DISEASE: A PILOT STUDY

Background:Behçet’s disease is a multisystemic vasculitis characterized by mucocutaneous, ocular, arthritic, and vascular manifestations.[1] However, the incidence and nature of cardiac involvement in Behcet’s disease have not been clearly documented yet.Objectives:This study aimed to assess the cardiac involvement in patients with Behçet’s disease using cardiac magnetic resonance imaging (MRI).Methods:This cross -sectional descriptive study was carried out on thirty consecutive patients with Behçet’s disease (21 males,9 females) with mean age 32.3±8.9 years and with no evidence of cardiac disease. They underwent cardiac MRI to determine morphological and functional changes of the heart and to detect areas of hyperenhancement after IV administration of gadolinium.Results:At least one abnormality on cardiac MRI was observed in 20/30 patients (66.67%). Myocardial oedema was observed in 3 patients (10.0%) and late gadolinium enhancement in only 1 patient (3.3%). Pericardial effusion was found in 3 patients (10.0 %), global hypokinesia in 6 patients (20.0%) and intra-cardiac thrombosis in only 1 patient (3.3%). Pulmonary artery was dilated in 4 patients (13.3%). Left ventricular and right ventricular end diastolic volume were altered in 4 patients (13.3 %) and 7 patients (23.3%) respectively. Also, left ventricular and right ventricular end systolic volume were abnormal in7 patients (23.3%) and 5 patients (16.7%) respectively. Moreover, there was aortic valve regurge in 2 patients (6.7%), tricuspid valve regurge in 9 patients (30%), and mitral valve regurge in 9 patients (30%).Dilated left main coronary artery in 2 patients (6.7%) and arythmogenic right ventricular dysplasia in only one patient 1 patient (3.3%).Conclusion:Behçet’s disease may cause cardiac abnormalities without clinical manifestations and cardiac MRI may represent a tool for early detection of these subtle abnormalities.References:[1]Geri, G., et al., Spectrum of cardiac lesions in Behçet disease: a series of 52 patients and review of the literature. Medicine, 2012.91(1): p. 25-34.Figure 1.Cardiac MRI in 32 year-old female patient with Behçet’s disease for 3 years.Acknowledgments: :The authors would like to acknowledge Ahmed El Bahy for his assistance with this studyDisclosure of Interests:None declared