scholarly journals POS0981 COMPUTED TOMOGRAPHY-BASED ASSESSMENT OF RADIOGRAPHIC PROGRESSION IN SPINE AND SACROILIAC JOINTS AFTER PREGNANCY IN WOMEN WITH ANKYLOSING SPONDYLITIS

2021 ◽  
Vol 80 (Suppl 1) ◽  
pp. 758.1-758
Author(s):  
K. A. Lee ◽  
S. Y. Lee ◽  
H. S. Kim ◽  
H. R. Kim ◽  
S. H. Lee
Keyword(s):  
Computed Tomography ◽  
Ankylosing Spondylitis ◽  
Radiographic Progression ◽  
Conventional Radiography ◽  
Joint Space ◽  
Ct Scans ◽  
Gravid Uterus ◽  
Pregnancy And Delivery ◽  
Ct Evaluation ◽  
Whole Spine

Background:Mechanical stress are one of the pathogenesis of ankylosing spondlitis (AS). During pregnancy, the mechanical overload on the spine and pelvis increases due to gravid uterus. Recently, computed tomography syndesmophyte score (CTSS) has been developed to analysis of the spinal damage in patients with AS. Indeed, CT has higher sensitivity and reliability compared to conventional radiography in the detection of sacroiliitis.Objectives:We aimed to investigate whether pregnancy and delivery affect radiographic progression of spine and SIJ in women with AS based on CT evaluation.Methods:This retrospective study included women aged 19-49 years with AS who performed at least twice CT scans of whole-spine or sacroilliac joints (SIJ) at intervals of 2 to 4 years. To compare the radiographic progression after delivery, we classified into 2 groups: delivery group or controls. Delivery group was restricted to subjects who had the first CT scans ~2 years before delivery and the second CT scans ~2 years after delivery. CTSS (0-522) and SIJ scores (0-40) were used to evaluate the spinal syndesmophyte and erosion, joint space narrowing, and sclerosis of SIJ.Results:A total of 21 women in delivery group and 38 women in controls were included. The median (Q1-Q3) CTSS at baseline in delivery group and controls were 19 (16-23) and 20 (13.25-27.75), and median progression was 1 (0-3) and 0 (0-1) during the median 2.9 year follow-up. The median (Q1-Q3) SIJ scores at baseline in delivery group and controls were 13 (8-22) and 11 (6-22), and median progression was 1.5 (0-3) and 1 (0-2). The CTSS and SIJ scores significantly increased in both groups, but no difference in absolute score changes per time point between was observed. The changes in SIJ scores was comparable according to the delivery methods.Conclusion:This study suggests that pregnancy and delivery had no effect on radiographic progression of spine and SIJ in female with AS.References:[1]de Bruin F, de Koning A, van den Berg R, Baraliakos X, Braun J, Ramiro S. Development of the CT Syndesmophyte Score (CTSS) in patients with ankylosing spondylitis: data from the SIAS cohort. 2018;77(3):371-7.Disclosure of Interests:None declared.

scholarly journals Computed Tomography-based Assessment of Radiographic Progression in Spine and Sacroiliac Joints After Pregnancy in Women With Ankylosing Spondylitis

2021 ◽  
Author(s):  
Kyung-Ann Lee ◽  
So Yun Lee ◽  
Se Hee Kim ◽  
Hyun-Sook Kim ◽  
Hae-Rim Kim ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Ankylosing Spondylitis ◽  
Radiographic Progression ◽  
Joint Space ◽  
Gravid Uterus ◽  
Control Group ◽  
Sacroiliac Joints ◽  
Pregnancy And Delivery ◽  
Whole Spine

Abstract Background: Mechanical stress are one of the pathogenesis of ankylosing spondylitis (AS). During pregnancy, the mechanical overload on the spine and pelvis increases due to gravid uterus. We aimed to investigate whether pregnancy affects radiographic progression in patients with ankylosing spondylitis (AS) based on computed tomography (CT) evaluations.Methods: This retrospective study included women with AS aged 19-49 years who underwent at least two CT evaluations of the whole spine or sacroiliac joints (SIJs) at intervals of 2-4 years. To compare radiographic progression after delivery, we classified the patients into two groups: delivery group and controls. The delivery group was restricted to women who had the first CT ~2 years before delivery and the second CT ~2 years after delivery. The CT Syndesmophyte Score (CTSS) (0-522) and SIJ scores (0-40) were used to evaluate spinal syndesmophytes and erosion, joint space narrowing, and sclerosis of the SIJs.Results: A total of 21 women in the delivery group and 38 women in the control group were included. The median (Q1-Q3) CTSS at baseline in the delivery group and controls was 19 (16-23) and 20 (13.25-27.75), and the median progression was 1 (0-3) and 0 (0-1) during the median 2.9-year follow-up, respectively. The median (Q1-Q3) SIJ score at baseline in the delivery group and controls was 13 (8-22) and 11 (6-22), and the median progression was 1.5 (0-3) and 1 (0-2), respectively. The CTSS and SIJ scores significantly increased in both groups; however, no difference in absolute score changes per time point was observed. The SIJ score changes were comparable according to the delivery method.Conclusion: Pregnancy and delivery do not affect the radiographic progression of the spine and SIJs in women with AS.

scholarly journals Computed tomography-based assessment of radiographic progression in spine and sacroiliac joints after pregnancy in women with ankylosing spondylitis

2021 ◽  
Author(s):  
Kyung-Ann Lee ◽  
So Yun Lee ◽  
Se Hee Kim ◽  
Hyun-Sook Kim ◽  
Hae-Rim Kim ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Retrospective Study ◽  
Ankylosing Spondylitis ◽  
Radiographic Progression ◽  
Sacroiliac Joints ◽  
Whole Spine ◽  
Time Point

Abstract We aimed to investigate whether pregnancy affects radiographic progression in patients with ankylosing spondylitis (AS) based on computed tomography (CT) evaluations. This retrospective study included women with AS aged 19–49 years who underwent at least two CT evaluations of the whole spine or sacroiliac joints (SIJs) at intervals of 2–4 years. The delivery group was restricted to women who had the first CT ~ 2 years before delivery and the second CT ~ 2 years after delivery. The CT Syndesmophyte Score (CTSS) (0-522) and SIJ scores (0–40) were used to radiographic progression. A total of 21 women in the delivery group and 38 women in the controls were included. The median (Q1-Q3) CTSS at baseline in the delivery group and controls was 19 (16–23) and 20 (13.25–27.75), and the median progression was 1 (0–3) and 0 (0–1) during the median 2.9-year follow-up, respectively. The median SIJ score at baseline in the delivery group and controls was 13 (8–22) and 11 (6–22), and the median progression was 1.5 (0–3) and 1 (0–2), respectively. The CTSS and SIJ scores significantly increased in both groups; however, no difference in absolute score changes per time-point was observed. Pregnancy do not affect the radiographic progression in AS.

Radiographic Assessment of the Feline Temporomandibular Joint with Oblique Projections: A Preliminary Ex Vivo Study

2021 ◽  
pp. 089875642110665
Author(s):  
Lenin A. Villamizar-Martinez ◽  
Cristian M. Villegas ◽  
Marco A. Gioso ◽  
Carina Outi Baroni ◽  
Silvana M. Unruh ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Temporomandibular Joint ◽  
Ex Vivo ◽  
Conventional Radiography ◽  
Joint Space ◽  
Domestic Cat ◽  
Radiographic Assessment ◽  
Oblique View ◽  
Oblique Projections ◽  
Complex Anatomy

Radiographic assessment of the temporomandibular joint in the domestic cat using conventional radiographic views can be challenging due to superimposition of overlying structures and the complex anatomy of the skull. The use of computed tomography, magnetic resonance imaging, and cone beam computed tomography to assess the temporomandibular joint in the cat has increased, but these modalities are not always available in general veterinary practices. Conventional radiography is still commonly used for first line assessment of the temporomandibular joint. The aim of this preliminary study was to determine optimal angle of obliquity of lateroventral-laterodorsal and laterorostral-laterocaudal (nose up lateral oblique) oblique radiographic views in the assessment of the temporomandibular joints in five feline mesaticephalic dry skulls. Visibility of the mandibular head, mandibular fossa, retroarticular process, and temporomandibular joint space were evaluated and scored by two veterinary radiologists. The results of this study identified that the dependent temporomandibular joint anatomy was best seen on the latero-10°-ventral-laterodorsal, latero-15°-ventral-laterodorsal, and latero-20°-ventral-laterodorsal, oblique views, and opposite lateral oblique views at these angulations may be helpful in characterization of this anatomy in clinical patients. The results also indicate that the laterorostral-laterocaudal (nose up lateral oblique) oblique view did not allow adequate discrimination of all TMJ anatomy at any angle, and is not recommended.

Computed Tomography and Conventional Radiography in Intrathoracic Metastases from Non-Seminomatous Testicular Tumor

1988 ◽  
Vol 29 (5) ◽  
pp. 547-549 ◽  
Author(s):  
H. H. Lien ◽  
L. Lindsköld ◽  
S. D. Fosså ◽  
N. Aass
Keyword(s):  
Computed Tomography ◽  
Lymph Nodes ◽  
Lung Metastases ◽  
Testicular Tumor ◽  
Lung Parenchyma ◽  
Conventional Radiography ◽  
Chest Radiographs ◽  
Ct Scans ◽  
Mediastinal Lymph Nodes ◽  
Posterior Mediastinal

Conventional chest radiographs and CT scans were studied retrospectively in 283 patients with untreated non-seminomatous testicular tumor. Intrathoracic metastases were found in 47 patients, and CT was the only positive examination in 20 of them. Lung metastases were seen in 39 patients and mediastinal lymph nodes were involved in 13. The additional yield of CT in detecting metastases was most marked for the lymph nodes (tumor detected only at CT in 9 out of 13 cases as compared with 14 out of 39 for the lung parenchyma). Posterior mediastinal and retrocrural lymph nodes were most often enlarged, and involvement of these was most difficult to detect at conventional radiography.

scholarly journals OP0250 MRI VERTEBRAL CORNER INFLAMMATION AND FAT DEPOSITION ARE ASSOCIATED WITH WHOLE SPINE LOW DOSE CT DETECTED SYNDESMOPHYTES: A MULTILEVEL ANALYSIS

2021 ◽  
Vol 80 (Suppl 1) ◽  
pp. 152.1-153
Author(s):  
R. Stal ◽  
X. Baraliakos ◽  
A. Sepriano ◽  
F. A. Van Gaalen ◽  
S. Ramiro ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Bone Formation ◽  
Thoracic Spine ◽  
Low Dose ◽  
Conventional Radiography ◽  
Fat Deposition ◽  
Magnetic Resonance Imaging Mri ◽  
Whole Spine ◽  
Low Dose Computed Tomography ◽  
Over Time

Background:A few studies have shown an association between vertebral corner inflammation (VCI) and vertebral corner fat deposition (VCFD) on MRI and syndesmophyte formation on cervical and lumbar conventional radiography.Objectives:To investigate whether magnetic resonance imaging (MRI) patterns of VCI, VCFD and a combination of both are associated with the development of new or grown syndesmophytes as detected by whole spine low dose computed tomography (ldCT), thereby studying these associations also in the thoracic spine.Methods:Patients in the Sensitive Imaging in Ankylosing Spondylitis cohort underwent MRI at baseline, 1 year and 2 years, and ldCT at baseline and 2 years. MRI lesions were scored by 3 central readers, using the SPARCC method for VCI and the CanDen method for VCFD, and coded as absent or present per timepoint and per reader. MRI patterns over time (Table) were based on patterns studied by Machado et al.1 and deemed present if seen by ≥2 out of 3 readers. The patterns reflect hypothetical associations between presence and absence of VCI and VCFD, independently and combined, on ldCT detected new or grown syndesmophytes. Individual reader change scores were used for ldCT images, scored by 2 central readers with the Computed Tomography Syndesmophyte Score. New (CTSS 0 to 1, 2 or 3) and grown (CTSS 1 to 2 or 3; 2 to 3) syndesmophytes were grouped together to represent bone formation. Corners not at risk for the outcome due to presence of a bridged syndesmophyte at baseline were excluded. Multilevel generalized estimated equations were used, with separate models per MRI pattern, accounting for correlations within patients and between ldCT readers.Table 1.Effect of vertebral corner inflammation and vertebral corner fat deposition on syndesmophyte formationPatterns of lesions over time on MRICorners with VCI/VCFD patternN(%)OR (95% CI)1. VCI at any TP, irrespective of VCFD691 (15.0%)2.37 (1.49-3.78)2. VCFD at any TP, irrespective of VCI1080 (23.5%)2.58 (1.97-3.39)3. VCI on ≥1 TP and absence of VCFD on all TPs372 (8.1%)1.90 (1.15-3.13)4. VCFD on ≥1 TP and absence of VCI on all TPs754 (16.4%)1.87 (1.41-2.48)5. VCI precedes VCFD43 (0.9%)2.20 (0.83-5.86)6. VCI precedes or coincides with VCFD. VCFD does not precede VCI198 (4.3%)2.33 (1.47-3.69)7. Absence of VCI and VCFD on all TPs3108 (67.6%)0.35 (0.25-0.49)VCI, vertebral corner inflammation; VCFD, vertebral corner fat deposition; TP, timepoint.Results:50 patients were included, contributing a total of 4600 vertebral corners. Their mean age was 49.3 years (SD 9.8), 86% were male and 78% were HLA-B27+. Presence of VCI and VCFD patterns ranged from 43 (0.9%) to 3108 (67.6%) corners (Table), with the lowest frequency being for VCI preceding VCFD. Protection against syndesmophyte development was seen in case of absence of both VCI and VCFD (OR 0.35) and positive associations with ORs ranging from 1.87-2.58 were observed for various VCI/VCFD patterns. Nevertheless, out of all corners with a new or grown syndesmophyte, 47.3% of corners according to reader 1 and 43.9% according to reader 2 had neither VCI nor VCFD preceding the bone formation.Conclusion:Presence of VCI or VCFD and combinations of the two, measured yearly on MRI, increased odds of bone formation 2 years later, whereas absence of both VCI and VCFD decreased the odds, showing that VCI and VCFD have some role in the development of syndesmophytes. However, almost half of all bone formation occurred in corners without VCI or VCFD, suggesting the presence of these lesions in yearly MRIs does not fully explain the development of syndesmophytes. This study confirmed that there is an association between VCI and VCFD and bone formation also for the thoracic spine and on ldCT compared to conventional radiography.References:[1]Machado et al ARD 2016Disclosure of Interests:Rosalinde Stal: None declared, Xenofon Baraliakos: None declared, Alexandre Sepriano: None declared, Floris A. van Gaalen Grant/research support from: Novartis, Sofia Ramiro: None declared, Rosaline van den Berg: None declared, Monique Reijnierse: None declared, Juergen Braun: None declared, Robert B.M. Landewé: None declared, Désirée van der Heijde: None declared

scholarly journals Low-dose CT detects more progression of bone formation in comparison to conventional radiography in patients with ankylosing spondylitis: results from the SIAS cohort

2017 ◽  
Vol 77 (2) ◽  
pp. 293-299 ◽  
Author(s):  
Anoek de Koning ◽  
Freek de Bruin ◽  
Rosaline van den Berg ◽  
Sofia Ramiro ◽  
Xenofon Baraliakos ◽  
...  
Keyword(s):  
Lumbar Spine ◽  
Ankylosing Spondylitis ◽  
Bone Formation ◽  
Thoracic Spine ◽  
Low Dose ◽  
Imaging Modality ◽  
Conventional Radiography ◽  
Low Dose Ct ◽  
Score Analysis ◽  
Whole Spine

ObjectivesTo compare the CT Syndesmophyte Score (CTSS) for low-dose CT (ldCT) with the modified Stoke Ankylosing Spondylitis Spine Score (mSASSS) for conventional radiographs (CR) in patients with ankylosing spondylitis (AS).MethodsPatients with AS in the Sensitive Imaging in Ankylosing Spondylitis cohort had lateral cervical and lumbar spine CR and whole spine ldCT at baseline and 2 years. CR and ldCT images were scored by two readers, paired by patient, blinded to time order, per imaging modality. For the total score analysis, we used average scores of readers per corner on CR or quadrant on ldCT. For the syndesmophyte analysis we used individual reader and consensus scores, regarding new or growing syndesmophyte at the same corner/quadrant.Results50 patients were included in the syndesmophyte analysis and 37 in the total score analysis. Mean (SD) status scores for mSASSS (range 0–72) and CTSS (range 0–552) at baseline were 17.9 (13.8) and 161.6 (126.6), and mean progression was 2.4 (3.8) and 17.9 (22.1). Three times as many patients showed new or growing syndesmophytes at ≥3 quadrants on ldCT compared with ≥3 corners on CR for individual readers; for consensus this increased to five times. In 50 patients, 36 new or growing syndesmophytes are seen on CR compared with 151 on ldCT, most being found in the thoracic spine.ConclusionsldCT, covering the whole spine, detects more progression in the form of new and growing syndesmophytes in patients with AS compared with CR, which is limited to the cervical and lumbar spine. Most progression occurred in the thoracic spine.

Cysticercosis of the Brain

1988 ◽  
Vol 29 (6) ◽  
pp. 625-628 ◽  
Author(s):  
J. Almeida-Pinto ◽  
J. A. Veiga-Pires ◽  
A. Stocker ◽  
T. Coelho ◽  
L. Monteiro
Keyword(s):  
Computed Tomography ◽  
Conventional Radiography ◽  
Therapeutic Management ◽  
Common Presentation ◽  
Radiologic Findings ◽  
Ct Evaluation ◽  
The Brain

Incidence and radiologic findings of neurocysticercosis were investigated in a series of 23 800 consecutive head examinations using computed tomography (CT). The condition was diagnosed in 168 cases (0.7%). The parenchymatous form was the most common presentation (96.3%), while the meningeal form corresponded to only 11.9 per cent of cases. These two forms coexisted in some cases. These findings reversed the knowledge on the condition based on conventional radiography. The different CT appearances in the brain are described and a new radiologic protocol for the CT evaluation of the condition is advocated, which includes a follow-up after a trial cure with Praziquantel in the presence of cysts not associated with suggestive brain calcifications. CT was more sensitive than conventional radiography in the differentiation between dead and living larvae, thus having an impact on the therapeutic management of the patients.

scholarly journals Comparison of X-Ray Imaging and Computed Tomography Scan in the Evaluation of Knee Trauma

Medicina ◽  
2019 ◽  
Vol 55 (10) ◽  
pp. 623
Author(s):  
Mustafa Avci ◽  
Nalan Kozaci
Keyword(s):  
Computed Tomography ◽  
Growth Plate ◽  
Predictive Value ◽  
Ct Scanning ◽  
Joint Space ◽  
Ct Scans ◽  
Automation System ◽  
Fracture Characteristics ◽  
X Ray ◽  
Knee Trauma

Background and objectives: The aim of the study was to compare the accuracy of X-ray (XR) imaging according to computed tomography (CT) scanning in the diagnosis of knee bone fractures, and in the determination of fracture characteristics, and to identify CT scan indications in patients with knee trauma. Materials and methods: The patients who presented to the emergency department (ED) due to knee trauma between January 2017 and December 2018 and who underwent XR imaging and CT scans were included in the study. XR images were reinterpreted by an emergency physician. The official reports, which had been interpreted by a radiologist in the hospital automation system for CT images, were considered valid. Results: Five hundred and forty-eight patients were included in the study. Of the patients, 200 (36.5%) had fractures in XR imaging and 208 (38.0%) had fractures in CT scans. Compared to CT scanning, XR imaging was found to have 89% sensitivity, 95% specificity, 92% positive predictive value, and 92% negative predictive value in identifying the fracture. The sensitivity of XR imaging in identifying growth plate fracture, angulation, stepping off, and extension of the fracture into the joint space was determined as 78% and less. According to the kappa value, there was determined a perfect concordance between the XR imaging and CT scans in angulation, stepping off, and extension of the fracture into the joint space. This concordance was moderate in growth plate fractures. Conclusions: XR imaging has a low sensitivity in identifying knee fractures. There is a moderate concordance between XR imaging and CT scanning in identifying growth plate fractures. Therefore, CT scanning should be performed in patients whose fracture type and fracture characteristics are not able to be determined exactly with XR imaging in knee injury.

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