scholarly journals Presence of atopy increases the risk of asthma relapse

2017 ◽  
Vol 103 (4) ◽  
pp. 346-351 ◽  
Author(s):  
Laurel Teoh ◽  
Ian M Mackay ◽  
Peter P Van Asperen ◽  
Jason P Acworth ◽  
Mark Hurwitz ◽  
...  
Keyword(s):  
Emergency Departments ◽  
Acute Asthma ◽  
Respiratory Viruses ◽  
Prick Test ◽  
Asthma Exacerbations ◽  
A Prospective Study ◽  
Micro Organisms ◽  
The Impact ◽  
Atypical Bacteria

ObjectivesTo describe the point prevalence of respiratory viruses/atypical bacteria using PCR and evaluate the impact of respiratory viruses/atypical bacteria and atopy on acute severity and clinical recovery in children with hospitalised and non-hospitalised asthma exacerbations.DesignThis was a prospective study performed during 2009–2011.SettingThe study was performed in the emergency departments of two hospitals.Patients244 children aged 2–16 years presenting with acute asthma to the emergency departments were recruited. A nasopharyngeal aspirate and allergen skin prick test were performed.Main outcome measuresThe outcomes were divided into (1) acute severity outcomes (Australian National Asthma Council assessment, hospitalisation, Functional Severity Scale, Acute Asthma Score, asthma quality of life questionnaires for parents (PACQLQ) on presentation, asthma diary scores (ADS) on presentation and length of hospitalisation) and (2) recovery outcomes (PACQLQ for 21 days, ADS for 14 days and representation for asthma for 21 days).ResultsPCR for viruses/atypical bacteria was positive in 81.7% of children (75.1% human rhinovirus, codetection in 14.2%). Mycoplasma pneumoniae and Chlamydophila pneumoniae were rarely detected. The presence of micro-organisms had little impact on acute asthma or recovery outcomes. Children with atopy were significantly more likely to relapse and represent for medical care by day 14 (OR 1.11, 95% CI 1.00 to 1.23).ConclusionsThe presence of any viruses is associated with asthma exacerbations but does not appear to influence asthma recovery. In contrast, atopy is associated with asthma relapse. M. pneumoniae and C. pneumoniae are rare triggers of acute asthma in young children.

Presence of Atopy Increases the Risk of Asthma Relapse

2017 ◽  
Author(s):  
Laurel Teoh ◽  
Ian Mackay ◽  
Peter P Van Asperen ◽  
Jason Acworth ◽  
Mark Hurwitz ◽  
...  
Keyword(s):  
Emergency Departments ◽  
Acute Asthma ◽  
Respiratory Viruses ◽  
Prick Test ◽  
Asthma Exacerbations ◽  
A Prospective Study ◽  
Micro Organisms ◽  
The Impact ◽  
Atypical Bacteria

AbstractObjectivesIn children with hospitalised and non-hospitalised asthma exacerbations, to: (a) describe the point prevalence of respiratory viruses/atypical bacteria using polymerase chain reaction (PCR) and; (b) evaluate the impact of respiratory viruses/atypical bacteria and atopy on acute severity and clinical recovery.DesignThis was a prospective study performed during 2009-2011.SettingThe study was performed in the Emergency Departments of 2 hospitals.Patients244 children aged 2-16 years presenting with acute asthma to the Emergency Departments were recruited. A nasopharyngeal aspirate and allergen skin prick test were performed.Main outcome measuresThe outcomes were divided into (a) acute severity outcomes [Australian National Asthma Council assessment, hospitalisation, Functional Severity Scale, acute asthma score, asthma quality of life questionnaires for parents (PACQLQ) on presentation, asthma diary scores (ADS) on presentation and length of hospitalisation] and (b) recovery outcomes (PACQLQ for 21 days, ADS for 14 days and representation for asthma for 21 days).ResultsPCR for viruses/atypical bacteria was positive in 81.7% of children (75.1% human rhinovirus, co-detection in 14.2%). M. pneumoniae and C. pneumoniae were rarely detected. The presence of micro-organisms had little impact on acute asthma or recovery outcomes. Children with atopy were significantly more likely to relapse and represent for medical care by day-14 (OR 1.11, 95%CI 1.00,1.23).ConclusionsThe presence of any viruses is associated with asthma exacerbations but does not appear to influence asthma recovery. In contrast, atopy is associated with asthma relapse. M. pneumoniae and C. pneumoniae are rare triggers of acute asthma in young children.

A prospective study of the impact of weight loss and the systemic inflammatory response on quality of life in patients with inoperable non-small cell lung cancer

Lung Cancer ◽  
2003 ◽  
Vol 40 (3) ◽  
pp. 295-299 ◽  
Author(s):  
Hazel R Scott ◽  
Donald C McMillan ◽  
Duncan J.F Brown ◽  
Lynn M Forrest ◽  
Colin S McArdle ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Lung Cancer ◽  
Weight Loss ◽  
Inflammatory Response ◽  
Prospective Study ◽  
Small Cell ◽  
Small Cell Lung ◽  
A Prospective Study ◽  
The Impact

scholarly journals Occupational and non-occupational allergic contact dermatitis and quality of life: a prospective study

2013 ◽  
Vol 88 (4) ◽  
pp. 670-671 ◽  
Author(s):  
Catiussa Spode Brutti ◽  
Renan Rangel Bonamigo ◽  
Taciana Cappelletti ◽  
Gabriela Mynarski Martins-Costa ◽  
Ana Paula Salin Menegat
Keyword(s):  
Quality Of Life ◽  
Statistical Difference ◽  
Life Questionnaire ◽  
Nickel Sulphate ◽  
Quality Of Life Questionnaire ◽  
General Data ◽  
A Prospective Study ◽  
Allergic Contact ◽  
The Impact

Attempted to evaluate and compare the impact on quality of life of occupational and non-occupational ACD and to identify the most frequently involved allergens. A quality of life questionnaire was applied. We noted moderate impact on the quality of life of both groups, without a statistical difference. Our study corroborates previous general data on the prevalence of nickel sulphate and paraphenylenediamine as the most common allergens. Potassium bichromate was shown to be one of the main occupational allergens and thimerosal as the main non-occupational allergen in our sample.

scholarly journals A PROSPECTIVE STUDY ON IMPACT OF PATIENT COUNSELLING ON QUALITY OF LIFE AND MEDICATION ADHERENCE IN EPILEPTIC PATIENTS

2016 ◽  
Vol 10 (1) ◽  
pp. 67
Author(s):  
Sathesh Kumar Sukumaran ◽  
Ayswarya P
Keyword(s):  
Quality Of Life ◽  
Medication Adherence ◽  
Patient Counseling ◽  
Chi Square ◽  
Patient Counselling ◽  
T Score ◽  
Epileptic Patients ◽  
A Prospective Study ◽  
The Impact

ABSTRACTObjective: To study the impact of patient counseling on medication adherence and quality of life (QOL) in epileptic patients and to assess the factorsaffecting medication adherence.Methods: This study is a prospective observational study involving 100 patients with an age limit of 8-60 years and those taking Antiepilepticdrugs for at least 3 months. The study population received patient counseling during their first visit. The impact of patient counseling on QOL andmedication adherence was assessed using self-reported questionnaire QOLIE-31 and MMAS-8 between the first visit and the second visit. Statisticalanalysis (Paired t-test and Paired Chi-square test) was performed to analyze the impact of patient counseling on QOL and medication adherence inepileptic patients.Results: A total of 100 patients were included in the study. After providing patient counseling, it was observed that there was a statistically significant(p<0.05) improvement in all domains of QOLIE-31 and MMAS-8 scores. Before counseling, mean overall T-score of QOLIE-31 was 44.08±2.07whichwas changed to 49.14±1.27 after patient counseling with a mean change of 5.06 in overall T-score. In the case of medication adherence, beforecounseling 77% subjects were nonadherent to therapy, after counseling it was reduced to 41%. The common reasons for medication adherence wereforgetfulness, unawareness, therapy related, and economics related. Out of which forgetfulness along with unawareness was the major one.Conclusion: The study described that patient counseling plays a major role in improving QOL and medication adherence.Keywords: QOLIE-31, MMAS-8, Epilepsy, Antiepileptic drugs, Patient counseling.

scholarly journals The impact of smoking cessation on patient quality of life

2009 ◽  
Vol 35 (5) ◽  
pp. 436-441 ◽  
Author(s):  
Maria Penha Uchoa Sales ◽  
Maria Irenilza Oliveira ◽  
Isabela Melo Mattos ◽  
Cyntia Maria Sampaio Viana ◽  
Eanes Delgado Barros Pereira
Keyword(s):  
Quality Of Life ◽  
Mental Health ◽  
Smoking Cessation ◽  
Short Form ◽  
Analysis Of Covariance ◽  
Sf 36 ◽  
Related Quality ◽  
A Prospective Study ◽  
The Impact

OBJECTIVE: To evaluate changes in health-related quality of life (HRQoL) after twelve months of smoking cessation. METHODS: This was a prospective study to evaluate the effectiveness of a smoking cessation program on the quality of life of 60 self-referred subjects, at a public hospital, during the period of August 2006 to December 2007. The program consisted of 2-h group sessions once a week during the first month and then every 15 days over six months, followed by monthly phone contacts for another six months. The treatment was based on behavior modification and the use of bupropion in combination with nicotinic replacement therapy. Abstinence was verified by exhaled CO measurements. Patient HRQoL was quantified using the Medical Outcomes Study 36-item Short-Form Health Survey (SF-36) questionnaire. Differences in quality of life scores between quitters and non-quitters at twelve months after the initial intervention were evaluated using analysis of covariance with baseline characteristics as covariates. RESULTS: Self-reported quality of life scores were significantly higher among the 40 quitters than among the 20 non-quitters. The following SF-36 domains were most affected: role-emotional (p = 0.008); general health (p = 0.006); vitality (p < 0.001); and mental health (p = 0.002). At twelve months after the smoking cessation intervention, the SF-36 mental component and physical component summary scores were higher among quitters than among non-quitters (p = 0.004 and p = 0.001, respectively). CONCLUSIONS: Our findings illustrate that smoking abstinence is related to better HRQoL, especially in aspects of mental health.

The impact of HLA-DR compatibility on cadaver kidney graft survival in a prospective study with special emphasis on the quality of typing

2008 ◽  
Vol 23 (2) ◽  
pp. 94-104 ◽  
Author(s):  
BODIL K. JAKOBSEN ◽  
ERIK LANGHOFF ◽  
PER PLATZ ◽  
LARS P. RYDER ◽  
JØRN HESS THAYSEN ◽  
...  
Keyword(s):  
Prospective Study ◽  
Graft Survival ◽  
Kidney Graft ◽  
Hla Dr ◽  
Cadaver Kidney ◽  
A Prospective Study ◽  
The Impact
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