scholarly journals Soft Tissue Tumor Leg - A Rare Presentation of Cutaneous Rhinosporidiosis

2020 ◽  
pp. 1-2
Author(s):  
R. Chithra ◽  
B Sai Dhandapani ◽  
R King Gandhi ◽  
R. Chithra

Rhinosporidiosis presents commonly as polypoidal growth in nose, but presentation in other sites including skin, genitourinary tract is documented. Cutaneous presentation is rare, which may present as pedunculated swelling or cutaneous ulceration, but presenting as soft tissue tumor is extremely rare. The multifaceted presentation of the disease causes diagnostic dilemma to an unsuspecting physician. Clinical and radiological findings may mislead, but usually typical history helps, and typical histology clinches the diagnosis. We are presenting a case of disseminated cutaneous rhinosporidiosis presented as soft tissue mass lesion in the leg causing diagnostic difficulty due to the rare presentation.

1974 ◽  
Vol 11 (1) ◽  
pp. 60-67 ◽  
Author(s):  
S.-K. Liu ◽  
H. D. Dorfman

A firm, poorly circumscribed soft tissue tumor occurred in the frontal and occipital or temporal musculature of four mature dogs aged 7-12 years. Radiographically, many nodular or stippled densities were scattered throughout the soft tissue mass, and the cranial bones were eroded. The tumor was characterized by nodular aggregations of proliferating chondrocytes surrounded by calcified matrix or chondroid ground substance. The intervening stroma was fibrous. These infiltrating fibrous lesions with calcified metaplastic cartilage have not been reported previously in the dog and are similar to calcifying aponeurotic fibroma in man.


2020 ◽  
Author(s):  
Gang Wu ◽  
Shili Wang ◽  
Chu Pan ◽  
Ting Wang

Abstract There are few publications regarding feasibility of readout-segmented diffusion tensor imaging (rsDTI) in assessing nerve invasion by soft tissue tumor. 64 patients with soft tissue mass in upper leg suspected of sciatic nerve invasion underwent rsDTI. Nerve invasion was confirmed in 28 cases by operation or electromyogram. The sciatic nerve was better depicted with diffusion weighted map versus b = 0 map of rsDTI. Inter-reader agreement in using rsDTI to rate nerve invasion was excellent. Sensitivity and specificity of rsDTI in identifying nerve invasion were 93% (26/28) and 92% (33/36) respectively. Apparent diffusion coefficient (ADC) was significantly higher in invaded nerves versus normal nerves (1.45 ± 0.67 × 10− 3mm2/s vs. 1.39 ± 0.46 × 10− 3mm2/s, P༜0.05). DTI derived FA was significantly lower in invaded nerves versus normal nerves (0.22 ± 0.11 vs. 0.37 ± 0.13, P༜0.05). Readout-segmented DTI was feasible in assessing sciatic nerve invasion by soft tissue tumor in selected patients.


2021 ◽  
Vol 14 (2) ◽  
pp. e236856
Author(s):  
Susruta Manivannan ◽  
Feras Sharouf ◽  
George Lammie ◽  
Paul Leach

Incidental soft tissue lumps in the scalp are a common presenting complaint in clinical practice. However, they may signify more sinister underlying pathologies. Our report examines a 63-year-old man presenting with impaired co-ordination in his left hand following a 3-month history of a painless left retroauricular scalp lump. MRI revealed a large left occipital soft tissue mass eroding through the underlying skull with infiltration into the underlying cerebellum and temporal lobe. Open biopsy confirmed a diagnosis of high-grade intracranial neuroendocrine tumour (NET). At approximately 5 months following successful tumour resection and adjuvant chemotherapy, he developed tumour recurrence and was subsequently palliated, and died at 1 year post diagnosis. Herein, we review other cases of primary intracranial NET, clinical findings, histopathological features and prognosis.


2021 ◽  
Vol 12 ◽  
pp. 220
Author(s):  
Christos Tzerefos ◽  
George K. Koukoulis ◽  
Marianna Vlychou ◽  
Alexandros G. Brotis ◽  
Kostas N. Fountas ◽  
...  

Background: Bursitis is a chronic inflammatory condition characterized by the deposition of cholesterol, macrophage infiltration, and bursal wall calcification. Bursitis is, however, rarely found in the sacrococcygeal region where it may present as a space-occupying mass. Case Description: A 64-year-old male with rheumatoid arthritis presented with 3 years’ duration of difficulty sitting and walking due to a soft-tissue mass involving the coccyx region. Once the patient’s MR demonstrated a cystic lesion with erosion of the coccyx, the patient underwent gross total resection of the lesion that proved to be pathologically consistent with bursitis. Postoperatively, the patient’s complaints fully resolved. Conclusion: Bursitis may present as a soft-tissue tumor-like lesion in the coccyx that favorably responds to gross total surgical excision.


Author(s):  
Nagadarshini Ramagiri Vinod ◽  
Hassan Tahir ◽  
Arslan Ahmed

Chronic osteomyelitis usually present as bony growth but it can rarely present as a soft tissue growth mimicking neoplasm and is usually diagnosed by the combination of radiology and microbiology. This is a case report of an adult male who had chronic osteomyelitis mimicking a neoplastic growth of soft tissue. CT scan showed soft tissue mass mimicking a soft tissue tumor but microbiology test and MRI confirmed the diagnosis of chronic osteomyelitis.


Blood ◽  
2016 ◽  
Vol 128 (22) ◽  
pp. 5185-5185
Author(s):  
Shahram Mori ◽  
Cai Yuan ◽  
Wesam B. Ahmed ◽  
Rushang D. Patel

Abstract Background: APL formerly known as AML M3 is a variant of myeloid malignancies characterized by recurrent cytogenetic abnormality of PML/RARA translocation, t(15;17). Myeloid sarcoma, also called granulocytic sarcoma or chloroma, is a very rare presentation of extramedullary APL. In rare cases seen, it presents mainly as CNS disease in relapsed or refractory patients. Extramedullary APL on initial presentation is even rarer. As a result no significant information exists on the prognosis of such patients. Case report: A 50-year-old Caucasian female with no past medical history, presented with 6-month duration of chest pain, which was treated as costochondritis without any improvement. Three months later, a soft tissue mass was identified on her sternum. Complete blood count revealed pancytopenia with white blood cell 3.24 x 103/uL, hemoglobin 10.0 g/dL, platelets 58x 103/uL, absolute neutrophil count 1.13 x103/uL, and monocytes 0.13 x103/uL which indicated "low risk disease". A PET/CT scan revealed a 4.6 cm x 4 cm sternal soft tissue mass. The biopsy of the mass confirmed myeloid sarcoma. Bone marrow biopsy showed acute promyelocytic leukemia, approximately 20% blasts in a hypercellular marrow with 70-80% cellularity. Cytogenesis test was negative. FISH analysis subsequently showed a partial RARA transcript inserted at the PML locus suggestive of a cryptic PML/RARA. This was confirmed by PCR for the fusion transcript PML/RARA from the bone marrow. Next generation genome sequencing identified FLT3/ITD and RUNX1 mutation. The patient was treated as a high risk disease due to the presence of chloroma and immediately started on treatment with Daunorubicin, Arsenic Trioxide (ATO), and All-Trans-Retinoic Acid (ATRA). Conclusion: We present an extremely rare case of APL initially presenting with concomitant extramedullary sternal soft tissue mass with cryptic t(15;17) and somatic mutations in FLT/ITD as well as RUNX1 mutations. To our knowledge this is the first reported case of extramedullary APL with FLT/ITD and RUNX1 mutations. Early recognition of this rare presentation with timely chemotherapy may improve the outcomes of these patients. Disclosures No relevant conflicts of interest to declare.


2018 ◽  
Vol 11 (1) ◽  
pp. e227615
Author(s):  
Shaan Patel ◽  
Key Yan Tsoi ◽  
George Joseph

A giant epidermal cyst is a benign soft tissue mass commonly involving the trunk, hand and face. The authors report a rare presentation of a 69-year-old man who presented with a painful, slow-growing left arm mass for 30 years duration. Examination revealed a large, mobile, soft tissue mass of the lateral aspect of the left arm. MRI showed a large, cystic left arm soft tissue mass. The mass was excised and the diagnosis of a giant epidermal cyst was made based on imaging and histopathology after surgical resection. The mass measured 9.5 cm x 8 cm x 4 cm, which is the largest reported giant epidermal cyst of the upper extremity.


2016 ◽  
Vol 10 (3) ◽  
pp. 270-273 ◽  
Author(s):  
Lauren K. Szolomayer ◽  
Paul G. Talusan ◽  
Wayne F. Chan ◽  
Dieter M. Lindskog

Leiomyoma is a benign soft-tissue tumor that can arise in any soft tissue; however, in the extremities, it is usually a subcutaneous mass. Masses in the foot and ankle in general are rare, and few reports in the literature describe leiomyoma in this region of the body. We present a series of 8 cases of leiomyoma of the foot and ankle, 4 of which are subclassified as angioleiomyomas. The characteristic patient presentation, imaging, and histological findings are presented here to increase awareness of this soft-tissue mass in the foot and ankle. Levels of Evidence: Level V


2021 ◽  
Vol 11 (8) ◽  
Author(s):  
Naoki Ishida

Introduction: Lipomas are the most common type of soft-tissue tumor, but intra-articular lipomas are very rare. Most cases occur in the knee joint. This is a report of intra-articular lipoma in the knee joint, 8 months after removal with good post-operative outcome. Case Report: A 56-year-old female who presented soft-tissue mass on her right knee. She felt uncomfortable but not in pain. The mass grew gradually and she wanted to be surgically removed. The mass was too large (5 cm × 4 cm × 2 cm) to be removed endoscopically, so arthrotomy was made. The mass was true lipoma histologically. She is living happily without recurrence after surgery. Conclusion: We have described an intra-articular synovial lipoma in the knee of a middle-aged female. Intra-articular lipomas are very rare. The tumor in this case was relatively large but painless, and the chief complaint was discomfort. It grew gradually, so the removal was performed. At present, the patient is living happy without recurrence after surgery. Keywords: Intra-articular lipoma, knee, removal, arthroscopy.


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